12 research outputs found
Entwicklung von Mess- und Analysentechniken zur Mikro- und Spurenbestimmung mittels Thermionen-Quadrupol-Massenspektrometrie Schlussbericht. Berichtszeitraum: 1. August 1982-31. Dezember 1984
SIGLETIB: D.Dt.F./AC 1000 (24,29) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman
Characterization and quantification of metallothionein isoforms by capillary electrophoresis inductively coupled plasma isotope dilution mass spectrometry
Aspects of the biogeochemistry of sulphur in glacial melt water ponds on the McMurdo Ice Shelf, Antarctica
Mass spectrometric isotope dilution analysis of small calcium concentrations in minerals
Characterization and quantification of metallothionein isoforms by capillary electrophoresis-inductively coupled plasma-isotope-dilution mass spectrometry
In a new approach to the characterization and quantification of metallothionein isoforms an on-line isotope-dilution method in combination with the coupling of capillary electrophoresis (CE) to an inductively coupled plasma-sector field mass spectrometer (ICP-SFMS) is reported. Metallothionein (MT) isoforms are separated by CE and the elements Cu, Zn, Cd, and S are detected simultaneously by use of ICP-SFMS in the medium resolution mode. On-line isotope dilution is performed by continuous introduction of an isotopically enriched, species-unspecific spike solution after the separation step. MT from rabbit liver and a further purified MT-1 isoform were quantified by determination of sulfur, and the stoichiometric compositions of the metalloprotein complexes are characterized by determination of their sulfur-to-metal ratios. (orig.)Reprinted from: Anal Bioanal Chem v. 372 (2002) p. 155-163Available from TIB Hannover: RA 3251(02/3) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman