The properties of electrolyte solutions in nonaqueous and mixed solvents

This paper constitutes a reviev of the results of investigations on electrolyte solutions in some organic solvents that behaves similarly to water from thermochemical point of vi,»w as well as in some water - organic mixed solvents. The investigations have been carried out in Physical Chemistry Department of University of Łódź in recent years.Zadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 dofinansowane zostało ze środków MNiSW w ramach działalności upowszechniającej naukę

Phase Behavior and Heat Capacity of {DPnP + Water} Mixtures at the Temperature Range of 273.15–338.15 K

Research ArticleThe differential scanning calorimetry method (DSC) was used to examine the miscibility in the {dipropylene glycol propyl ether (DPnP) + water} system

Modification of the Two-Point Scaling Theory for the Description of the Phase Transition in Solution. Analysis of Sodium Octanoate Aqueous Solutions

On the basis of conventional scaling theory, the two-point scaling theory was modified in order to describe the influence of composition on the partial molar heat capacity and volume during the micellization process. To verify the theory, isobaric heat capacities and densities of aqueous sodium octanoate solutions were measured over wide composition and temperature ranges and the modified approach was used to analyze the calculated partial molar heat capacities and volumes of the surfactant in water. The results obtained indicate that the micellization process is subject to the scaling laws. The results were compared with those for other systems. Peculiar behavior of the critical indices was observed and correlated with the structure of the micelles

The differences in thermal profiles between normal and leukemic cells exposed to anticancer drug evaluated by differential scanning calorimetry

Chronic lymphocytic leukemia (CLL) is a heterogenous disease with an imbalance between apoptosis and cell proliferation. Therefore, the main goal in CLL therapy is to induce apoptosis and effectively support this process in transformed B lymphocytes. In the current study, we have compared differential scanning calorimetry (DSC) profiles of nuclei isolated from CLL cells and normal mononuclear cells exposed to cladribine or fludarabine combined with mafosfamide (CM; FM), and additionally to CM combined with monoclonal antibody—rituximab (RCM) for 48 h, as well as in culture medium only (controls). Under current study, the mononuclear cells from peripheral blood (PBMCs) of healthy individuals have been included. The obtained results have shown the presence of thermal transition at 95 ± 5 °C in most of nuclear preparations (92.2 %) isolated from blood of CLL patients. This thermal characteristic parameter was changed after drug exposure, however, to a different extent. These thermal changes were accompanied by the decrease of cell viability, an elevation of apoptosis rate and the changes in expression/proteolysis of poly(ADP-ribose)polymerase-1—main marker of apoptosis. Importantly, in DSC profiles of nuclear preparations of PBMCs from blood of healthy donors exposed to investigated drug combinations and control CLL cells, the lack of such changes was observed. Our results confirmed that DSC technique complemented with other biological approaches could be helpful in tailoring therapy for CLL patients.Research was sponsored by Grant from the Polish National Science Centre (No. 2011/01/B/NZ/0102); Results of presented study were partially presented in oral presentation on 2nd Central and Eastern European Conference on Thermal Analysis and Calorimetry in Vilnius, Lithuania, 201

Wpływ własności rozpuszczalnika na entalpię przeniesienia elektrolitów z wody do rozpuszczalników organicznych i mieszanin wodno-organicznych

Zadanie pt. Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki nr 885/P-DUN/2014 zostało dofinansowane ze środków MNiSW w ramach działalności upowszechniającej naukę

Thermodynamic Interaction between PAMAM G4-NH2, G4-OH, G3.5-COONa Dendrimers and Gemcitabine in Water Sotutions

The thermodynamics of complex formation of polyamideamine dendrimers: cationic PAMAM G4-NH2, neutral PAMAM G4-OH and anionic PAMAM G3.5-COONa with gemcitabine hydrochloride, an antitumor drug, in water at a temperature of 250C was studied. The investigations were carried out with the use of ITC measurements allowing one to determine the number of the drug molecules bonded by the dendrimer macromolecule, the equilibrium constants of the complex formed and the values of enthalpy and entropy of their formation. The measurements results obtained show different numbers of the drug molecules bonded by dendrimer macromolecules depending on the properties of their terminal groups

Kryteria tworzenia i burzenia struktury wody przez elektrolity

A la base des données accessibles, contenues dans la litterature et qui concernent l‘interaction ion-eau, on a procédé à une analyse critique de l'application des termes de promoteur ("structure making") et de briseur ("structure breaking"). On a attéré l'attention sur le fait que la compréhension des notions ci-dessus par différents chercheurs est loin d'être unanime. On a prouvé que les diverses méthodes expérimentales aboutissent souvent à des conclusions différentes au sujet de l’influence exercée par les ions sur la structure de l'eau. On a exprimé l’opinion que l'application des termes de "promoteur“ et de "briseur" devrait être limitée au critère entropique.Na podstawie danych literaturowych dotyczących oddziaływań jon-woda przeprowadzono krytyczną analizę stosowalności terminów "structure making" i “structure breaking". Wskazano na niejednoznaczne rozumienie tych pojęć przez różnych badaczy. Wykazano, że różne metody doświadczalne prowadzą często do niejednakowych wniosków odnośnie do wpływu jonów na struktury wody. Wyrażono opinię, że stosowanie terminów "structure making" i "structure breaking" powinno być ograniczone do kryterium entropowego.Zadanie pt. Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki nr 885/P-DUN/2014 zostało dofinansowane ze środków MNiSW w ramach działalności upowszechniającej naukę