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Not AvailableAn outbreak of keratoconjunctivitis was reported in a dairy farm at north Goa district, of Goa State, where a herd of bulls was showing conjunctivitis, lachrymal discharge, corneal opacity in single or both eyes. Animals were emaciated due to blindness and hence the inability to move and feed. Injuries due to sudden falling and collisions were also noticed. Preliminary clinical examination revealed that the animals had infectious bovine keratoconjunctivitis. Isolation and identification of the pathogen from the ocular swab revealed the presence of Moraxella spp. Multiplex PCR identified the causative agent as M. bovoculi. The isolate was confirmed as M.bovoculi by sequence analysis of the 16srRNA gene. Treatment using Streptomycin and Penicillin antibiotics and dexamethasone was started in affected animals, which yielded good results and complete recovery. Phylogenetic analysis showed clustering of the isolate with isolates from India and United States.Not Availabl

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Not AvailableThis newsletter for the period January to June describes various activities undertaken by the Scientists of ICAR-NIVEDI.Not Availabl

Development and Validation of UV-Spectrophotometric Method for Estimation of Vinpocetine in Marketed Formulation and Nanoformulation

A quick, accurate, and cost-effective UV spectroscopy method was developed to estimate the Vinpocetine concentration in bulk, tablet dosage formulations and niosomes formulations, using a solvent ratio of (6:4) methanol: water. According to ICH guidelines, the proposed technique was validated and developed. In spite of linearity, precision, accuracy, specificity, LOD, and LOQ, like parameters were validated by using UV/visible spectroscopy technique to analyze a spiked Vinpocetine solution. The wavelength at which the drug's maximum absorbance peak was obtained at 274 nm and the solvents used as methanol: water (6:4 w/v). The ethanol injection technique was used to prepare niosomes to analyze Vinpocetine in UV / visible spectrophotometric method.During the inter and intra-day studies, it was discovered that the developed UV technique was accurate, with % relative standard deviation ranging from 0.27 to 0.46 and 0.26 to 0.46, respectively. Vinpocetine overall recovery percentage was discovered to be between 98.42 to 99.82 %. LOQ and LOD were calculated to estimate the method's sensitivity, and they were observed to be 0.4565 µg/ml and 0.1506 µg/ml, respectively. The estimation of Vinpocetine content in bulk form, marketed formulations and niosomes was achieved using the developed methodology. : A quick, accurate, and economical UV spectrophotometric method has been developed. As a result, the suggested UV spectroscopic technique has been developed to estimate the vinpocetine concentration in bulk, tablet dosage formulations, and niosomes formulations

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ICAR Short Course Training Manual on Techniques in pig semen processing and Artificial InseminationICAR Short Course Training Manual on Techniques in pig semen processing and Artificial InseminationNot Availabl

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Not AvailableHighlights the research and various activities undertaken during the year 2020 by ICAR-NIVEDI scientistsNot Availabl

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Not AvailableHighlights the research and various activities undertaken during the year 2021 by ICAR-NIVEDI scientistsNot Availabl