Analysis of Nosql Database State-of-The-Art Techniques and their Security Issues

NOSql database systems are extremely optimized for performing retrieval and adjoining operations on large quantity of data as compared to relational models which are relatively inefficient. They are used majorly for real-time applications and statistically analyzing the growing amount of data. NoSQL databases emerging in market claim to outperform SQL databases. In Present time of technology, every person wants to save and secure   its data so that no one can check their information without their permission .However, there are multifarious security issues which are yet to be resolved. In this paper, we are discussing and reviewing about the Nosql databases and their most popular security issues link (Cassandra and Mongo DB)

Role of electrode materials in the Electrochemical Oxidation of Malachite Green dye

The aim of the present study is to degrade Malachite green (MG) dye electrochemically, which is become an alternative attractive method in recent years. The degradation of dye was studied in KCl as supporting electrolyte medium at graphite anode and platinum cathode under amperostatic condition. The variation of the dye concentration was accessed by UV-Visible measurements and Chemical oxygen demand (COD) reductions were also performed. The results clearly shown that at the optimum conditions(current density = 1.805 mA cm-2, initial dye concentration = 100 mgL-1, KCl concentration = 5 gL-1, Temperature = 25 ± 2 °C, pH = 4, electrode gap = 1 cm), 99% MG degradation and 82% of reduction in COD was achieved within 120 min during electrolysis with maximum energy resource management, i.e., 21.212 KWh kg-1. The reaction mechanism of electrocatalytic MG degradation was characterized with mass spectrum and Fourier transform infrared spectroscopy (FT-IR). Kinetic studies showed that at different initial dye concentration degradation takes place through a first order diffusion controlled reaction. The study showed that electrochemical oxidation is a superior technology for treatment of Malachite green with maximum power management after 120 min of electrolysis treatment

Investigation of Lysozyme Refolding Using Ionic Liquids as Refolding Additives

A rapid and inexpensive method for the production of protein is crucial for the biopharmaceutical industry. The bottleneck in the case of genetically engineered systems lies in the recovery of active and properly refolded proteins from inclusion bodies. The correct refolding of a protein from its denatured state is dependent on several parameters including the concentration of the protein, the refolding buffers utilized, the approach employed and finally the type of refolding additives, if any, used in the process. In this study, an emerging class of refolding additives, namely, ionic liquids were investigated for the refolding of denatured lysozyme protein. Lysozyme was used as a model system due to its rapid refolding kinetics and the fact that enzyme based assay could be carried out to measure the refolding yields. The ionic liquids selection was hypothesized based on the selection of cation and anion that constitute the ionic liquid. The efficacy of Imidazolium based ionic liquids as refolding additives was compared to conventional refolding approach that contains urea and redox-couple cysteine/cystine. Using response surface methodology (RSM) and central composite design (CCD), an empirical model was developed and validated by experimental results. Different refolding strategies were also evaluated; dilution refolding, adsorptive on column packed bed refolding and adsorptive on column fluidized bed refolding. Experimental results indicate that in comparison to the conventional refolding buffer, among different ionic liquids examined, ionic liquid [EMIM]Cl has a pronounced effect on the refolding yield and time required to refold the denatured lysozyme. The optimal conditions were identified in this study as 150 μg/ml of denatured lysozyme in presence of 75 mM [EMIM] Cl in 50 mM HEPES buffer (pH 7.5). On-column refolding studies indicate that in comparison to the packed bed system, the fluidized bed ion-exchange system approach, with [EMIM] Cl as the elution-refolding buffer could tolerate higher concentration of denatured lysozyme (up to 25 mg) with refolding yield ca. 90% and fractional mass recovery ca. 82%. This was due to potentially lower mass transfer limitations in the fluidized bed compared to the packed bed. Thus, the versatility of ionic liquids coupled with on-column adsorptive refolding can possibly be the solution to the large scale downstream processing of proteins

Energy Return on Investment Analysis of a Solar Photovoltaic System

The consumption of petroleum product assets on an overall premise has required an earnest look for elective vitality sources to get together the present-day request. The world likewise faces the double difficulties of petroleum derivative exhaustion and CO2 discharges plus the fundamental competitor for confronting these difficulties. However, safe and economic concepts for CCS have not been proven, nuclear suffer from high cost, radioactive waste management, fuel availability, and nuclear weapon proliferation issues, and renewable, other than hydropower, have been limited by resource limits, high cost, and intermittency problems. In any case, the later intense cost decreases in the creation of photovoltaics (PV) which makes ready for empowering sun-based innovations to end up cost focused on petroleum energy generation. The target of present work is to evaluate the capability of sun oriented solar power at Chandigarh University, which lastly built up a framework depending on the potential estimations for a picked region of 1050.1416 m2. At the end, cost estimation of SPV is determined to indicate whether it is monetarily practical or not

Variability in Semidiurnal Surface and Internal Tides in Global Ocean Model Simulations

This dissertation focuses on semidiurnal (D2) surface and internal tides. Chapter 2 investigates the transition of M2 barotropic Kelvin waves into Hybrid Kelvin-Edge (HKE) waves and the associated generation of internal tides at widening shelves using theory and a realistic global baroclinic Hybrid Coordinate Ocean Model (HYCOM) simulation. To understand the effect of complex, realistic bathymetry on the HKE wave transition, we perform quasi-realistic barotropic HYCOM simulations of the Celtic Sea/Bay of Biscay shelf areas. We conclude that the HKE wave transition is most likely masked by the effects of complex bathymetry and offshelf baroclinic fluxes cannot be exclusively attributed to the HKE wave transition. In Chapter 3, we study the seasonal variability of total (stationary and non-stationary) D2 internal tide and the phase-locked (stationary) M2 internal tide sea surface height (SSH) using global HYCOM simulations and altimeter datasets. The internal tides generated in the coastal regions of Georges Bank and the Arabian Sea feature the strongest seasonal variability. The amplitude of the seasonal cycle and the seasonal arrival times (phase) of the semidiurnal internal tides in the HYCOM simulation agree with these observed in the altimetry data. However, the variance (amplitude) of M2 steric sea surface height (SSSH) in the HYCOM simulation is about 70% (20%) larger than in the altimeter observations. Even after applying a correction for bottom pressure, the HYCOM SSSH remains larger than the altimetry M2 variance. Chapter 4 compares the seasonal variability observed in the D2 SSSH variance with D2 internal tide energetics using global HYCOM simulations and an altimeter dataset. The seasonal trends of monthly SSSH variance and energetics are in phase in Georges Bank and the Arabian Sea. However, outside these hotspots, the seasonal variability in D2 energetics is out of phase with D2 SSSH variance. While the seasonal variability in D2 energy is driven by seasonal changes in barotropic to baroclinic conversion at topography, D2 SSSH variance is also modulated by seasonal changes in surface stratification. Hence, one should be careful in interpreting the temporal variability in internal tide SSH as the true internal tide variability, which is better determined from energetics

Protecting Internet Access: A Human Rights Treaty Approach

With the evolution of the internet, the world has also seen a marked increase in government-ordered internet shutdowns and restrictions, sometimes with dubious justifications and sometimes with no justification at all. As people have become increasingly reliant on the internet for their day-to-day activities and to keep up with important news, internet restrictions often disrupt lives and violate people’s civil and human rights. While no international law directly protects internet access, it is implicitly advocated for under the freedom of opinion and expression. The upward trend of internet restrictions, however, suggests that an implied protection of access to a necessary resource is not enough. Greater monitoring and vetting are needed to discourage unnecessary restrictions and to encourage accountability when restrictions are imposed. An international or multilateral treaty is usually accompanied by a treaty committee, which oversees how successfully States parties honor their commitments. Accordingly, a treaty committee would be in a unique position to monitor and vet internet restrictions imposed by States parties, which would discourage the practice of unnecessary internet restrictions. This Note examines recent internet restrictions in India, Ethiopia, and Venezuela with a focus on the reasons given for the restrictions as well as their impact. Rather than simply proposing the establishment and provisions of a multilateral treaty, this Note explores how this treaty could be practicably implemented and monitored by its treaty committee by taking lessons from the existing multilateral treaty framework

Characterization of the RNAP Binding Sites on a λ DNA using a Solid State Nanopore Combined with a Tuning Fork Force Sensing Probe Tip

In this dissertation, the binding positions of RNAP holoenzyme on a λ DNA are characterized using an apparatus that integrates a Solid State Nanopore with a Tuning Fork based Force sensing probe (SSN-TFFSP). The SSN-TFFSP system combines the measurement of ionic current through a solid-state nanopore with a DNA tethered probe tip. The position of the tip is sensed by a tuning fork force sensor and is controlled with a nanopositioning system. With this apparatus, translocation speed of DNA through solid state nanopores has been brought down to 100 μs/base. Such a controlled movement of DNA through a solid state nanopore can provide enough temporal resolution to determine the individual binding site of a RNAP on a λ DNA. Three signals measured simultaneously from this apparatus were: ionic current through a nanopore, tip position, and tip vibrational amplitude. These signals were measured when the probe tip was approaching towards the nanopore and was being lifted away from the pore. The λ DNA+ RNAP complex tethered to the probe tip can be captured by the electric field near a nanopore. The nanopore current signal measured during the capture of RNAP bound λ DNA provides new insights to the dynamics of λ DNA+RNAPcomplex molecules inside the nanopore. The binding positions of RNAP on a λ DNA are measured directly from the tip position signal corresponding to the distinct current drop within λ DNA current blockage level. The resolution limit of this apparatus is estimated to be 100 nm or 300 bp for RNAP binding sites. The resolution limit was further compared with the free translocation data set of λ DNA+RNAPcomplex through the solid state nanopore

An Analysis on Different Methods of Data Mining Techniques with Its Purposes and Issues

It is not wrong to say that the advancement in the technology has a great impact on the human society. It has been altered the way of doing business, providing and receiving the services, managing the organizations etc. The most direct effect is the completed change of 3 information collection, conveying, and exchange. Data mining is an emerging domain that is specifically applied to extract the meaningful data from the large amount of available contents. Various authors have been developed the various prominent methods to for data mining. This study generates a review to the data mining and along with this a brief introduction to the knowledge discovery data base is also given in this work. Difference data extraction processes are cover under this by author