1,434 research outputs found

    Which Osteotomy for Osteonecrosis of the Femoral Head and Which Patient for the Osteotomy?

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    Transtrochanteric curved varus osteotomy (TCVO) and transtrochanteric rotational osteotomy (TRO) are joint-preserving procedures for osteonecrosis of the femoral head. The purpose of this review is to provide up-to-date guidelines for the osteotomies. One retrospective comparison revealed that TCVO has shorter operation time, less bleeding, lower incidence of osteophyte formation, and lower rate of secondary collapse. To obtain successful results of the osteotomy, the patient should be younger than 40 years and should have a body mass index of less than 24 kg/m2. The osteotomy should be performed in early stages of femoral head osteonecrosis before marked collapse of the femoral head. The patient should have a medium-size lesion and an enough viable bone to restore the intact articular surface and subchondral bone in the weight-bearing area

    Delayed Presentation of Renocolic Fistula at 4 Months after Blunt Abdominal Trauma

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    Causes of previously reported reno-colic fistulas included primary renal and colonic pathologic states involving infectious, malignant or other inflammatory processes. However, reno-colic fistula after renal injury is extremely uncommon. We report an unusual delayed presentation of reno-colic fistula that occurred at 4 months later after blunt abdominal trauma

    Physical and electrochemical properties of synthesized carbon nanotubes [CNTs] on a metal substrate by thermal chemical vapor deposition

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    Multi-walled carbon nanotubes were synthesized on a Ni/Au/Ti substrate using a thermal chemical vapor deposition process. A Ni layer was used as a catalyst, and an Au layer was applied as a barrier in order to prevent diffusion between Ni and Ti within the substrate during the growth of carbon nanotubes. The results showed that vertically aligned multi-walled carbon nanotubes could be uniformly grown on the Ti substrate (i.e., metal substrate), thus indicating that the Au buffer layer effectively prevented interdiffusion of the catalyst and metal substrate. Synthesized carbon nanotubes on the Ti substrate have the diameter of about 80 to 120 nm and the length of about 5 to 10 μm. The Ti substrate, with carbon nanotubes, was prepared as an electrode for a lithium rechargeable battery, and its electrochemical properties were investigated. In a Li/CNT cell with carbon nanotubes on a 60-nm Au buffer layer, the first discharge capacity and discharge capacity after the 50th cycle were 210 and 80 μAh/cm2, respectively

    Laparoscopic Removal of a Broken Sewing Needle in a Patient with Irritative Bladder Symptoms

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    A foreign body near the bladder is rare. Although foreign bodies in the bladder can be easily found and removed by endoscopic transurethral removal, extravesical foreign bodies may require the use of an open or laparoscopic procedure. Here, we report a case of a patient complaining of frequency and urgency in whom an extravesical sewing needle was successfully removed by a laparoscopic approach. A 4.5 cm rusty sewing needle was found between the bladder and the left external iliac vessels and was removed through a 5 mm trocar port by use of endo forceps with no complications

    Crystallization and preliminary crystallographic studies of an antimicrobial protein from Pharbitis nil

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    An antimicrobial protein from seeds of Pharbitis nil (Pn-AMP) which shows an antifungal activity towards several agriculturally important plant pathogens has been crystallized in the presence of equimolar N-acetylglucosamine with sodium citrate as precipitant. The crystal belongs to the hexagonal space group P6(1)22 (or P6(5)22), with unit-cell parameters a = b = 29.33 (5), c = 133.44 (12) Angstrom. Native data were collected using a crystal at 100 K to a resolution of 1.78 Angstrom.open2

    A Strategic Assessment of Needs and Opportunities for the Wider Adoption of Electric Vehicles in Indiana

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    INDOT plans to invest nearly $100 million to build a statewide electric vehicle (EV) charging network as part of the National Electric Vehicle Infrastructure Formula Program. SPR-4509 Phase-I identified energy EV charging deserts in Indiana for long-distance trips. SPR-4509 Phase-II further examines the charging stations\u27 impact on EV long-distance trips in Indiana. Using an agent-based simulation model, the number of charges, vehicle miles traveled, energy used during the trip, and energy used during charging were estimated for nine different cases. High EV daily charging demand areas in Indiana were shown in ArcGIS based on multiple scenarios of different charging station construction phases and EV market penetration rates. The study findings can inform the state’s EV charging plan development

    Selective uptake of epidermal growth factor-conjugated gold nanoparticle (EGF-GNP) facilitates non-thermal plasma (NTP)-mediated cell death

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    Non-thermal atmospheric pressure plasma (NTP) has been shown to induce cell death in various mammalian cancer cells. Accumulated evidence also shows that NTP could be clinically used in cancer therapy. However, the current NTP-based applications lack target specificity. Here, a novel method in NTP-mediated cancer therapeutics was described with enhanced target specificity by treating EGF (epidermal growth factor)-conjugated GNP (gold nanoparticle). The treatment with EGF-conjugated GNP complex, followed by NTP irradiation showed selective apoptosis of cells having receptor-mediated endocytosis. NTP triggered gamma-H2AX elevation which is a typical response elicited by DNA damage. These results suggest that EGF-conjugated GNP functions as an important adjuvant which gives target specificity in applications of conventional plasma therapy.111Ysciescopu

    Chromosome-level genome assembly of a regenerable maize inbred line A188

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    Background: The maize inbred line A188 is an attractive model for elucidation of gene function and improvement due to its high embryogenic capacity and many contrasting traits to the first maize reference genome, B73, and other elite lines. The lack of a genome assembly of A188 limits its use as a model for functional studies. Results: Here, we present a chromosome-level genome assembly of A188 using long reads and optical maps. Comparison of A188 with B73 using both whole-genome alignments and read depths from sequencing reads identify approximately 1.1 Gb of syntenic sequences as well as extensive structural variation, including a 1.8-Mb duplication containing the Gametophyte factor1 locus for unilateral cross-incompatibility, and six inversions of 0.7 Mb or greater. Increased copy number of carotenoid cleavage dioxygenase 1 (ccd1) in A188 is associated with elevated expression during seed development. High ccd1 expression in seeds together with low expression of yellow endosperm 1 (y1) reduces carotenoid accumulation, accounting for the white seed phenotype of A188. Furthermore, transcriptome and epigenome analyses reveal enhanced expression of defense pathways and altered DNA methylation patterns of the embryonic callus. Conclusions: The A188 genome assembly provides a high-resolution sequence for a complex genome species and a foundational resource for analyses of genome variation and gene function in maize. The genome, in comparison to B73, contains extensive intra-species structural variations and other genetic differences. Expression and network analyses identify discrete profiles for embryonic callus and other tissues

    Trace Expression of r-th Root over Finite Field

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    Efficient computation of rr-th root in Fq\mathbb F_q has many applications in computational number theory and many other related areas. We present a new rr-th root formula which generalizes Müller\u27s result on square root, and which provides a possible improvement of the Cipolla-Lehmer algorithm for general case. More precisely, for given rr-th power cFqc\in \mathbb F_q, we show that there exists αFqr\alpha \in \mathbb F_{q^r} such that Tr(α(i=0r1qi)rr2)r=cTr\left(\alpha^\frac{(\sum_{i=0}^{r-1}q^i)-r}{r^2}\right)^r=c where Tr(α)=α+αq+αq2++αqr1Tr(\alpha)=\alpha+\alpha^q+\alpha^{q^2}+\cdots +\alpha^{q^{r-1}} and α\alpha is a root of certain irreducible polynomial of degree rr over Fq\mathbb F_q
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