Effects of legume cover crop and sub-soiling on soil properties and Maize (Zea mays L) growth in semi arid area of Machakos district, Kenya = Efecto del cultivo de cobertua y el subsolado sobre las propiedades del suelo y crecimiento de maiz (Zea mays L.) en la region semi arida de Machakos, Kenia

Low crop yields in the semi arid areas of Kenya have been attributed to, among other factors, low soil fertility, low farm inputs, labour constraints and inappropriate tillage practices that lead to pulverized soils. The aim of this study was to determine the effects of legume cover crops (LCC) on soil properties and maize growth in the semi arid area of Machakos District, Kenya. The study was undertaken in farmers’ fields. The field experiments were carried out in a RCBD with four treatments each replicated four times during the 2008 long (LR) and short rain (SR) seasons. The treatments were T1 = maize + dolichos (Lablab purpureus) + subsoiling; T2 = maize + dolichos + no subsoiling; T3 = maize alone + no subsoiling; T4 = maize alone with subsoiling). Results from the field experiments showed that rainfall amount and its distribution affected the growth and yield of dolichos and maize. There were significant differences in ground cover between the treatments at P = 0.05 in all the different weeks after planting when measurements were taken. The penetration resistance in all the plots ranged from 3.83 - 4.18 kg cm-2 with treatment T4 having the highest and treatment T1 lowest penetration resistance. There were also siginificant changes in soil N in plots which were under dolichos compared to plots without dolichos. The results obtained in this study also indicated that subsoiling in combination with dolichos had the greatest potential of improving soil properties and crop yields in semi arid environments of Kenya

Divergent consensuses on Arctic amplification influence on midlatitude severe winter weather

The article of record as published may be found at https://doi.org/10.1038/s41558-019-0662-yWe thank R. Blackport, C. Deser, L. Sun, J. Screen and D. Smith for discussions and suggested revisions to the manuscript. We also thank J. Screen and L. Sun for model data. A. Amin helped to create Fig. 2. US CLIVAR logistically and financially supported the Arctic-Midlatitude Working Group and Arctic Change and its Influence on Mid-Latitude Climate and Weather workshop that resulted in this article. J.C. is supported by the US National Science Foundation grants AGS-1657748 and PLR-1504361, 1901352. M.W. acknowledges funding by the Deutsche Forschungsgemeinschaft project no. 268020496– TRR 172, within the Transregional Collaborative Research Center “Arctic Amplification: Climate Relevant Atmospheric and Surface Processes, and Feedback Mechanisms (AC)3 ”. T.V. was supported by the Academy of Finland grant 317999. J.O. was supported by the NOAA Arctic Research Program. J.F. was supported by the Woods Hole Research Center. S.W. and H.G. are supported by the US DOE Award Number DE-SC0016605. J.Y. was supported by the Korea Meteorological Administration Research and Development Program under grant KMI2018-01015 and National Research Foundation grant NRF_2017R1A2B4007480. D.H. is supported by the Helmholtz Association of German Research Centers (grant FKZ HRSF-0036, project POLEX). The authors acknowledge the World Climate Research Programme’s Working Group on Coupled Modelling, which is responsible for CMIP, and thank the climate modelling groups (listed in Supplementary Table 1) for producing and making available their model output. For CMIP, the US Department of Energy’s PCMDI provides coordinating support and led development of software infrastructure in partnership with the Global Organization for Earth System Science Portals.The Arctic has warmed more than twice as fast as the global average since the late twentieth century, a phenomenon known as Arctic amplification (AA). Recently, there have been considerable advances in understanding the physical contributions to AA, and progress has been made in understanding the mechanisms that link it to midlatitude weather variability. Observational studies overwhelmingly support that AA is contributing to winter continental cooling. Although some model experiments sup port the observational evidence, most modelling results show little connection between AA and severe midlatitude weather or suggest the export of excess heating from the Arctic to lower latitudes. Divergent conclusions between model and observational studies, and even intramodel studies, continue to obfuscate a clear understanding of how AA is influencing midlatitude weather

Spectrum of pheochromocytoma in the 131 I-MIBG era

131 I-metaiodobenzylguanidine ( 131 I-MIBG) scintigraphy allows for both functional diagnosis and anatomical localization of pheochromocytoma. The spectrum of pheochromocytoma since the routine use of preoperative 131 I-MIBG scan was studied. From 1980 to 1986, a total of 34 patients were primarily diagnosed and treated at the University of Michigan Medical Center, Ann Arbor, Michigan, U.S.A. There were 16 males and 18 females. The mean age was 38 years and 4 patients (11.8%) were under 18 years of age. Six patients (17.6%) had family history of pheochromocytoma or multiple endocrine neoplasia (MEN) II syndrome. The presenting symptoms were hypertension in 29 patients (85.3%); attacks of headache, palpitation, sweating, and flushing in 4 (11.8%), and 1 patient presented with a neck mass. Plasma catecholamines were elevated in 97% of patients while urinary catecholamines and metabolites were elevated in 93.5%. 131 I-MIBG was accurate in 82.3%, partly positive in 11.8%, and false-negative in 5.9% of patients. CT scan was accurate in 80%, partly positive in 10%, but failed to show the tumor in another 10% of patients. At operation, extraadrenal lesions were found in 38.2% of the patients and among these, one-third were extraabdominal. Multiple tumors occurred in 5 (14.7%), and bilateral adrenal lesions occurred in 4 patients (11.8%). Malignancy was diagnosed in 3 patients (8.8%) after an average follow-up period of 2 years. We conclude that the use of routine preoperative 131 I-MIBG scanning improves localization of pheochromocytoma and earlier diagnosis is possible in patients with MEN II syndrome. Multiple tumors, extraadrenal and extraabdominal lesions occur more often than commonly believed. The low rate of confirmed malignancy is probably related to the short period of follow-up. La scintigraphie à l' 131 I-MIBG permet de diagnostiquer et de localiser les phéochromocytomes. Toute la gamme de types de phéochromocytomes reconnu depuis l'utilisation préopératoire systématique de la scintigraphie à l' 131 I-MIBG est présentée. Entre 1980 et 1986, 34 patients ont été explorés et traités au Centre Médical de l'Université de Michigan, Ann Arbor, Michigan. Il y avait 16 hommes et 18 femmes. L'âge moyen était de 38 ans, et 4 patients (11.8%) avaient moins de 18 ans. Six patients (17.6%) avaient des antécédents familiaux de phéochromocytome ou de néoplasmes endocrines multiples (MEN) du type II. Les symptômes amenant à consulter étaient l'hypertension chez 29 patients (85.3%), des crises de céphalées, des palpitations et un flush chez 4 patients (11.8%); un patient présentait une masse cervicale. Les catécholamines plasmatiques étaient élevées chez 97% des patients alors que les catécholamines et leurs métabolites étaient en quantité élevée chez 93.5% des patients. La scintigraphie à l' 131 I-MIBG était positive chez 82.3%, partiellement positive chez 11.8%, et faussement négative chez 5.9% des patients. La tomodensitométrie était positive chez 80%, partiellement positive chez 10%, et faussement négative chez 10% des patients. A l'intervention, des lésions extra-surrénales étaient présentes dans 38.2% des cas, et parmi celles-ci, un tiers étaient extra-abdominales. Les tumeurs étaient multiples dans 5 cas (14.7%), et bilatérales surrénales dans 4 cas (11.8%). Une tumeur maligne était diagnostiquée chez 3 patients (8.8%), après une période de suivi de 2 ans en moyenne. Nous concluons que l'utilisation systématique de la scintigraphie à l' 131 I-MIBG améliore la localisation des phéochromocytomes, permettant un diagnostic plus précoce chez les patients présentant un syndrome MEN II. La multiplicité tumorale et les localisations extra-médullosurrénales ou extra-abdominales se voient beaucoup plus fréquemment qu'on le pensait auparavant. Le taux de malignité peu élevé était probablement en rapport avec la courte période de suivi. La escintigrafía con 131 I-MIBG permite tanto la localización anatómica como el diagnóstico funcional del feocromocitoma. Las características o espectro del feocromocitoma a partir del uso rutinario de 131 I-MIBG han sido estudiadas.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41282/1/268_2005_Article_BF01655447.pd

Genetic, abiotic and social influences on sex differentiation in cichlid fishes and the evolution of sequential hermaphroditism

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73799/1/j.1467-2979.2005.00184.x.pd

Structure and Function of the Hair Cell Ribbon Synapse

Faithful information transfer at the hair cell afferent synapse requires synaptic transmission to be both reliable and temporally precise. The release of neurotransmitter must exhibit both rapid on and off kinetics to accurately follow acoustic stimuli with a periodicity of 1 ms or less. To ensure such remarkable temporal fidelity, the cochlear hair cell afferent synapse undoubtedly relies on unique cellular and molecular specializations. While the electron microscopy hallmark of the hair cell afferent synapse — the electron-dense synaptic ribbon or synaptic body — has been recognized for decades, dissection of the synapse’s molecular make-up has only just begun. Recent cell physiology studies have added important insights into the synaptic mechanisms underlying fidelity and reliability of sound coding. The presence of the synaptic ribbon links afferent synapses of cochlear and vestibular hair cells to photoreceptors and bipolar neurons of the retina. This review focuses on major advances in understanding the hair cell afferent synapse molecular anatomy and function that have been achieved during the past years