On the modified dispersion-controlled dissipative (DCD) scheme for computation of flow supercavitation

10.1016/j.compfluid.2010.10.001Computers and Fluids401315-323CPFL

Geometric criterion for RR↔MR transition in hypersonic double-wedge flows

10.1063/1.862466Physics of Fluids2211-9PHFL

Visualization of calcium phosphate cement in teeth by zero echo time H-1 MRI at high field

Contains fulltext : 184112.pdf (publisher's version ) (Closed access

Crystal structure and electronic and thermal properties of TbFeAsO0.85

The crystal structure and the electronic and thermal properties of a high-quality polycrystalline TbFeAsO0.85 sample made by a high-pressure technique are investigated. The crystal structure, as determined by synchrotron X-ray powder diffraction, possesses a tetragonal unit cell (space group: P4/nmm) with lattice parameters of a=b=3.8851 Å and c =8.3630 Å. In order to elucidate the electronic structure and oxidation states of corresponding elements, X-ray absorption near-edge structure (XANES) spectra are presented. The XANES spectra confirm that the oxidation states of Fe, As, and Tb in the TbFeAsO0.85 sample are ~Fe2+, ~As3−, and ~Tb3+, respectively, which are consistent with the previously reported band structure calculations. The n-type character of the charge carriers as revealed from XANES spectra is corroborated by the negative sign of the Seebeck coefficient (S) in the present study. The heat capacity (CP) measurement shows an anomaly in the vicinity of the superconducting transition temperature (Tc=42.5 K), which confirms the bulk nature of the superconductivity in this material

A theranostic dental pulp capping agent with improved MRI and CT contrast and biological properties

Contains fulltext : 177800.pdf (publisher's version ) (Closed access)Different materials have been used for vital dental pulp treatment. Preferably a pulp capping agent should show appropriate biological performance, excellent handling properties, and a good imaging contrast. These features can be delivered into a single material through the combination of therapeutic and diagnostic agents (i.e. theranostic). Calcium phosphate based composites (CPCs) are potentially ideal candidate for pulp treatment, although poor imaging contrast and poor dentino-inductive properties are limiting their clinical use. In this study, a theranostic dental pulp capping agent was developed. First, imaging properties of the CPC were improved by using a core-shell structured dual contrast agent (csDCA) consisting of superparamagnetic iron oxide (SPIO) and colloidal gold, as MRI and CT contrast agent respectively. Second, biological properties were implemented by using a dentinogenic factor (i.e. bone morphogenetic protein 2, BMP-2). The obtained CPC/csDCA/BMP-2 composite was tested in vivo, as direct pulp capping agent, in a male Habsi goat incisor model. Our outcomes showed no relevant alteration of the handling and mechanical properties (e.g. setting time, injectability, and compressive strength) by the incorporation of csDCA particles. In vivo results proved MRI contrast enhancement up to 7weeks. Incisors treated with BMP-2 showed improved tertiary dentin deposition as well as faster cement degradation as measured by microCT assessment. In conclusion, the presented theranostic agent matches the imaging and regenerative requirements for pulp capping applications. STATEMENT OF SIGNIFICANCE: In this study, we combined diagnostic and therapeutic agents in order to developed a theranostic pulp capping agent with enhanced MRI and CT contrast and improved dentin regeneration ability. In our study we cover all the steps from material preparation, mechanical and in vitro characterization, to in vivo study in a goat dental model. To the best of our knowledge, this is the first time that a theranostic pulp capping material have been developed and tested in an in vivo animal model. Our promising results in term of imaging contrast enhancement and of induction of new dentin formation, open a new scenario in the development of innovative dental materials