70 research outputs found
No cosmological domain wall problem for weakly coupled fields
After inflation occurs, a weakly coupled scalar field will in general not be
in thermal equilibrium but have a distribution of values determined by the
inflationary Hubble parameter. If such a field subsequently undergoes discrete
symmetry breaking, then the different degenerate vacua may not be equally
populated so the domain walls which form will be `biased' and the wall network
will subsequently collapse. Thus the cosmological domain wall problem may be
solved for sufficiently weakly coupled fields in a post-inflationary universe.
We quantify the criteria for determining whether this does happen, using a
Higgs-like potential with a spontaneously broken symmetry.Comment: 17 pages, 4 figures (Revtex), clarifying Comments added in
Introduction; to appear in Phys. Rev
Geophysical constraints on mirror matter within the Earth
We have performed a detailed investigation of geophysical constraints on the
possible admixture of mirror matter inside the Earth. On the basis of the
Preliminary Reference Earth Model (PREM) -- the `Standard Model' of the Earth's
interior -- we have developed a method which allows one to compute changes in
various quantities characterising the Earth (mass, moment of inertia, normal
mode frequencies etc.)due to the presence of mirror matter. As a result we have
been able to obtain for the first time the direct upper bounds on the possible
concentration of the mirror matter in the Earth. In terms of the ratio of the
mirror mass to the Earth mass a conservative upper bound is . We then analysed possible mechanisms (such as lunar and solar tidal
forces, meteorite impacts and earthquakes) of exciting mirror matter
oscillations around the Earth centre. Such oscillations could manifest
themselves through global variations of the gravitational acceleration at the
Earth's surface. We conclude that such variations are too small to be observed.
Our results are valid for other types of hypothetical matter coupled to
ordinary matter by gravitation only (e.g. the shadow matter of superstring
theories).Comment: 25 pages, in RevTeX, to appear in Phys.Rev.
Family-based obesity prevention for infants: Design of the “Mothers & Others” randomized trial
Objective Our goal is to test the efficacy of a family-based, multi-component intervention focused on infants of African-American (AA) mothers and families, a minority population at elevated risk for pediatric obesity, versus a child safety attention-control group to promote healthy weight gain patterns during the first two years of life. Design, participants, and methods The design is a two-group randomized controlled trial among 468 AA pregnant women in central North Carolina. Mothers and study partners in the intervention group receive anticipatory guidance on breastfeeding, responsive feeding, use of non-food soothing techniques for infant crying, appropriate timing and quality of complementary feeding, age-appropriate infant sleep, and minimization of TV/media. The primary delivery channel is 6 home visits by a peer educator, 4 interim newsletters and twice-weekly text messaging. Intervention families also receive 2 home visits from an International Board Certified Lactation Consultant. Assessments occur at 28 and 37 weeks gestation and when infants are 1, 3, 6, 9, 12, and 15 months of age. Results The primary outcome is infant/toddler growth and likelihood of overweight at 15 months. Differences between groups are expected to be achieved through uptake of the targeted infant feeding and care behaviors (secondary outcomes) and change in caregivers' modifiable risk factors (mediators) underpinning the intervention. Conclusions If successful in promoting healthy infant growth and enhancing caregiver behaviors, “Mothers and Others” will have high public health relevance for future obesity-prevention efforts aimed at children younger than 2 years, including interventional research and federal, state, and community health programs. Trial Registration ClinicalTrials.gov, NCT01938118, August 9, 2013
Monte Carlo reconstruction of the inflationary potential
We present Monte Carlo reconstruction, a new method for ``inverting''
observational data to constrain the form of the scalar field potential
responsible for inflation. This stochastic technique is based on the flow
equation formalism and has distinct advantages over reconstruction methods
based on a Taylor expansion of the potential. The primary ansatz required for
Monte Carlo reconstruction is simply that inflation is driven by a single
scalar field. We also require a very mild slow roll constraint, which can be
made arbitrarily weak since Monte Carlo reconstruction is implemented at
arbitrary order in the slow roll expansion. While our method cannot evade
fundamental limits on the accuracy of reconstruction, it can be simply and
consistently applied to poor data sets, and it takes advantage of the attractor
properties of single-field inflation models to constrain the potential outside
the small region directly probed by observations. We show examples of Monte
Carlo reconstruction for data sets similar to that expected from the Planck
satellite, and for a hypothetical measurement with a factor of five better
parameter discrimination than Planck.Comment: 10 pages, 5 figures (RevTeX 4) Version submitted to PRD: references
added, minor clarification
Inflation at Low Scales: General Analysis and a Detailed Model
Models of inflationary cosmology based on spontaneous symmetry breaking
typically suffer from the shortcoming that the symmetry breaking scale is
driven to nearly the Planck scale by observational constraints. In this paper
we investigate inflationary potentials in a general context, and show that this
difficulty is characteristic only of potentials dominated near their
maxima by terms of order . We find that potentials dominated by terms
of order with \hbox{} can satisfy observational constraints at
an arbitrary symmetry breaking scale. Of particular interest, the spectral
index of density fluctuations is shown to depend only on the order of the
lowest non-vanishing derivative of near the maximum. This result is
illustrated in the context of a specific model, with a broken
symmetry, in which the potential is generated by gauge boson loops.Comment: Submitted to Phys. Rev. D. 32 Pages, REVTeX. No figure
Explaining through the synthesis of ordinary matter from mirror matter: a more general analysis
The emerging cosmological picture is of a spatially flat universe composed
predominantly of three components: ordinary baryons (),
non-baryonic dark matter () and dark energy
(). We recently proposed that ordinary matter was
synthesised from mirror matter, motivated by the argument that the observed
similarity of and suggests an underlying similarity
between the fundamental properties of ordinary and dark matter particles. In
this paper we generalise the previous analysis by considering a wider class of
effective operators that non-gravitationally couple the ordinary and mirror
sectors. We find that while all considered operators imply
few, only a subset quantitatively reproduce the observed ratio
. The eV mass scale induced
through these operators hints at a connection with neutrino oscillation
physics.Comment: minor changes, some references added, about 10 page
An Inflationary Scenario Taking into Account of Possible Dark Energy Effects in the Early Universe
We investigate the possible effect of cosmological-constant type dark energy
during the inflation period of the early universe. This is accommodated by a
new dispersion relation in de Sitter space. The modified inflation model of a
minimally-coupled scalar field is still able to yield an observation-compatible
scale-invariant primordial spectrum, simultaneously having potential to
generate a spectrum with lower power at large scales. A qualitative match to
the WMAP 7-year data is presented. We obtain an of the same
order of that in the -CDM model. Possible relations between the de
Sitter scenario and the Doubly Special Relativity(DSR) are also discussed.Comment: 17 pages, 3 figuire
New insights into the genetic etiology of Alzheimer's disease and related dementias
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele
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