INFLUENCE DU MILIEU THERMIQUE SUR L'ÉVOLUTION DE LA TEMPÉRATURE RECTALE ET DE LA GLYCÉMIE CHEZ LE PORCELET NOUVEAU-NÉ

International audienc

INFLUENCE DU MILIEU THERMIQUE SUR L'ÉVOLUTION DE LA TEMPÉRATURE RECTALE ET DE LA GLYCÉMIE CHEZ LE PORCELET NOUVEAU-NÉ

With the changes in lifestyle, eating habits and new training methodologies, it becomes important that scientific research fills gaps in anthropometric and nutritional knowledge fields, with the purpose of improving martial arts and combat sports athletes’ physical fitness and performance during competition and training. This study aimed to assess the nutritional status and knowledge in martial arts fighters, and relate it to their perception of body image. We evaluated 37 male fighters, who practiced different forms of martial arts in two academies in west São Paulo. To measure the nutritional status body weight, height and skinfolds were assessed. The perception of body image and nutritional knowledge were also assessed. The sample showed an average of 25 ± 5 years, 84.4 ± 15.78 kg, 1.76 ± 0.07 m and fat percentage of 14.12 ± 5.46. The mean body mass index was 26.95 ± 3.75 kg/m², which means they were overweight. 70.27% of the fighters had moderate nutritional knowledge, 24.32% low knowledge and the remaining 5.41% high knowledge. In relation to the nutritional status, the fighters were mostly overweight and had fat percentage below average, with high body image dissatisfaction and moderate nutritional knowledge.Con los cambios en el estilo de vida, los hábitos alimentarios y en las nuevas metodologías de entrenamiento, es importante que la investigación científica explore las lagunas existentes en los campos de conocimiento antropométrico y nutricional, con el fin de mejora la aptitud física y el rendimiento de los atletas de artes marciales y deportes de combate durante las competiciones y los entrenamientos. El presente estudio tuvo como objetivo evaluar el conocimiento y estado nutricional de luchadores de artes marciales, y relacionarlo con la percepción de la imagen corporal. Se evaluaron 37 atletas practicantes de diferentes modalidades de artes marciales en dos academias en la zona oeste de São Paulo. Para determinar el estado nutricional se midieron la masa corporal, la estatura y los pliegues cutáneos. También se evaluaron la percepción de la imagen corporal y el conocimiento nutricional. La muestra presentó en promedio 25,8 ± 5,8 años, 84,4 ± 15,8 kg, 1,76 ± 0,07 m y un porcentaje de grasa de 14,1 ± 5,5. La media del índice de masa corporal fue de 26,95 ± 3,75 kg / m², clasificando a los atletas con sobrepeso. Un 70,27% del total de luchadores presentó un conocimiento nutricional moderado, el 24,32% un bajo conocimiento y el restante 5,41% un alto conocimiento. En cuanto al estado nutricional, los luchadores presentaron en su mayoría sobrepeso y un porcentaje de grasa por debajo de la media, con gran insatisfacción de imagen corporal y moderado conocimiento nutricional.Com as mudanças no estilo de vida, hábitos alimentares e novas metodologias de treinamento tornam-se importantes pesquisas científicas, para preencher as lacunas no conhecimento antropométrico e nutricional, com finalidade de melhora na aptidão física e desempenho durante as competições e treinamentos para atletas de artes marciais e esportes de combate. O presente estudo teve como objetivo avaliar o conhecimento e estado nutricional assim como relacionar com a percepção da imagem corporal em lutadores de artes marciais. Avaliou-se 37 atletas, que praticavam diferentes modalidades de artes marciais provenientes de duas academias na zona oeste de São Paulo. Para determinar o estado nutricional foram mensuradas a massa corporal, estatura e dobras cutâneas; também a percepção da imagem corporal e o conhecimento nutricional. A amostra apresentou em média 25,8 ± 5,8 anos, 84,4 ± 15,8 kg, 1,76 ± 0,07 m e percentual de gordura de 14,1 ± 5,5. A média do índice de massa corporal foi de 26,95 ± 3,75 kg/m², classificando-os com sobrepeso. Dos lutadores, 70,27% apresentaram moderado conhecimento nutricional, 24,32% baixo conhecimento e o restante 5,41% alto conhecimento. Em relação ao estado nutricional, os lutadores apresentavam em sua maioria sobrepeso e percentual de gordura abaixo da média, com grande insatisfação de imagem corporal e moderado conhecimento nutricional

Doravirine plus lamivudine two-drug regimen as maintenance antiretroviral therapy in people living with HIV: a French observational study

International audienceBackground: Two-drug regimens based on integrase strand transfer inhibitors (INSTIs) and boosted PIs have entered recommended ART. However, INSTIs and boosted PIs may not be suitable for all patients. We aimed to report our experience with doravirine/lamivudine as maintenance therapy in people living with HIV (PLWH) followed in French HIV settings.Methods: This observational study enrolled all adults who initiated doravirine/lamivudine between 1 September 2019 and 31 October 2021, in French HIV centres participating in the Dat'AIDS cohort. The primary outcome was the rate of virological success (plasma HIV-RNA < 50 copies/mL) at Week (W)48. Secondary outcomes included: rate of treatment discontinuation for non-virological reasons, evolution of CD4 count and CD4/CD8 ratio over follow-up.Results: Fifty patients were included, with 34 (68%) men; median age: 58 years (IQR 51-62), ART duration: 20 years (13-23), duration of virological suppression: 14 years (8-19), CD4 count: 784 cells/mm3 (636-889). Prior to switching, all had plasma HIV-RNA < 50 copies/mL. All but three were naive to doravirine, and 36 (72%) came from a three-drug regimen. Median follow-up was 79 weeks (IQR 60-96). Virological success rate at W48 was 98.0% (95% CI 89.4-99.9). One virological failure occurred at W18 (HIV-RNA = 101 copies/mL) in a patient who briefly discontinued doravirine/lamivudine due to intense nightmares; there was no resistance at baseline and no resistance emergence. There were three strategy discontinuations for adverse events (digestive disorders: n = 2; insomnia: n = 1). There was no significant change in CD4/CD8 ratio, while CD4 T cell count significantly increased.Conclusions: These preliminary findings suggest that doravirine/lamivudine regimens can maintain high levels of viral suppression in highly ART-experienced PLWH with long-term viral suppression, and good CD4+ T cell count