78 research outputs found
Mean first passage time analysis reveals rate-limiting steps, parallel pathways and dead ends in a simple model of protein folding
We have analyzed dynamics on the complex free energy landscape of protein
folding in the FOLD-X model, by calculating for each state of the system the
mean first passage time to the folded state. The resulting kinetic map of the
folding process shows that it proceeds in jumps between well-defined, local
free energy minima. Closer analysis of the different local minima allows us to
reveal secondary, parallel pathways as well as dead ends.Comment: 7 page
Extended quantum critical phase in a magnetized spin-1/2 antiferromagnetic chain
Measurements are reported of the magnetic field dependence of excitations in
the quantum critical state of the spin S=1/2 linear chain Heisenberg
antiferromagnet copper pyrazine dinitrate (CuPzN). The complete spectrum was
measured at k_B T/J <= 0.025 for H=0 and H=8.7 Tesla where the system is ~30%
magnetized. At H=0, the results are in quantitative agreement with exact
calculations of the dynamic spin correlation function for a two-spinon
continuum. At high magnetic field, there are multiple overlapping continua with
incommensurate soft modes. The boundaries of these continua confirm
long-standing predictions, and the intensities are consistent with exact
diagonalization and Bethe Ansatz calculations.Comment: 4 pages, 4 figure
Holomorphic mappings from the ball and polydisc
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46216/1/208_2005_Article_BF01351851.pd
Probing impulsive strain propagation with x-ray pulses
Pump-probe time-resolved x-ray diffraction of allowed and nearly forbidden
reflections in InSb is used to follow the propagation of a coherent acoustic
pulse generated by ultrafast laser-excitation. The surface and bulk components
of the strain could be simultaneously measured due to the large x-ray
penetration depth. Comparison of the experimental data with dynamical
diffraction simulations suggests that the conventional model for impulsively
generated strain underestimates the partitioning of energy into coherent modes.Comment: 4 pages, 2 figures, LaTeX, eps. Accepted for publication in Phys.
Rev. Lett. http://prl.aps.or
Longitudinal exchange: an alternative strategy towards quantification of dynamics parameters in ZZ exchange spectroscopy
Longitudinal exchange experiments facilitate the quantification of the rates of interconversion between the exchanging species, along with their longitudinal relaxation rates, by analyzing the time-dependence of direct correlation and exchange cross peaks. Here we present a simple and robust alternative to this strategy, which is based on the combination of two complementary experiments, one with and one without resolving exchange cross peaks. We show that by combining the two data sets systematic errors that are caused by differential line-broadening of the exchanging species are avoided and reliable quantification of kinetic and relaxation parameters in the presence of additional conformational exchange on the msâÎŒs time scale is possible. The strategy is applied to a bistable DNA oligomer that displays different line-broadening in the two exchanging species
Picosecond soft x-ray absorption measurement of the photoinduced insulator-to-metal transition in VO
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