3,089 research outputs found

    Histograms in heavy-quark QCD at finite temperature and density

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    We study the phase structure of lattice QCD with heavy quarks at finite temperature and density by a histogram method. We determine the location of the critical point at which the first-order deconfining transition in the heavy-quark limit turns into a crossover at intermediate quark masses through a change of the shape of the histogram under variation of coupling parameters. We estimate the effect of the complex phase factor which causes the sign problem at finite density, and show that, in heavy-quark QCD, the effect is small around the critical point. We determine the critical surface in 2+1 flavor QCD in the heavy-quark region at all values of the chemical potential mu including mu=infty.Comment: 26 pages, 21 figures, 1 tabl

    An experimental and computational investigation of the flow field about a transonic airfoil in supercritical flow with turbulent boundary-layer separation

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    A combined experimental and computational research program is described for testing and guiding turbulence modeling within regions of separation induced by shock waves incident in turbulent boundary layers. Specifically, studies are made of the separated flow the rear portion of an 18%-thick circular-arc airfoil at zero angle of attack in high Reynolds number supercritical flow. The measurements include distributions of surface static pressure and local skin friction. The instruments employed include highfrequency response pressure cells and a large array of surface hot-wire skin-friction gages. Computations at the experimental flow conditions are made using time-dependent solutions of ensemble-averaged Navier-Stokes equations, plus additional equations for the turbulence modeling

    Causes and Outcomes of Spontaneous Pneumothoraces in Solid Tumor Cancer Patients: An Update for the Medical Oncologist

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    PurposeDefined as lung collapse in the absence of a recent invasive thoracic procedure, a spontaneous pneumothorax can be a catastrophic event, leading to abrupt shortness of breath, chest pain, hypotension, and occasionally death. A dearth of present day information on this entity in solid tumor cancer patients prompted this single-institution retrospective study on current causes and outcomes.MethodsAll patients with diagnoses of “spontaneous pneumothorax” and “cancer” between 1990 and 2004 had their records retrieved and reviewed. Among 546 patients with a diagnosis of spontaneous pneumothorax, only 25 (5%) met predefined inclusion criteria that included an antecedent diagnosis of an invasive solid tumor malignancy. Lung (n = 5) and bladder cancer (n = 4) were the most common malignancies; eight patients had received radiation and one had received carmustine. Of note, 78% were smokers, 13 had chronic obstructive pulmonary disease, and 12 had no known active cancer at the time of the pneumothorax.ResultsPneumothorax management was associated with great morbidity, including hospitalization in 24 patients and chest tube placement and/or surgery in most patients. Median survival for the group as a whole was 31 months, but patients with known active cancer tended to do poorly, with only a 3-month median survival.ConclusionA spontaneous pneumothorax is rare, and patients with known active cancer tend to do poorly. However, even patients with no known active cancer are at risk, perhaps in part from smoking. The fact that patients with no known active cancer can live for years after this event suggests that the pneumothorax should not be assumed to be related to cancer recurrence, that cancer restaging is not always mandatory, and that there is justification for managing the pneumothorax in this subgroup aggressively

    The counterbend phenomenon in flagellar axonemes and cross-linked filament bundles

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    Recent observations of flagellar counterbend in sea urchin sperm show that the mechanical induction of curvature in one part of a passive flagellum induces a compensatory countercurvature elsewhere. This apparent paradoxical effect cannot be explained using the standard elastic rod theory of Euler and Bernoulli, or even the more general Cosserat theory of rods. Here, we develop a geometrically exact mechanical model to describe the statics of microtubule bundles that is capable of predicting the curvature reversal events observed in eukaryotic flagella. This is achieved by allowing the interaction of deformations in different material directions, by accounting not only for structural bending, but also for the elastic forces originating from the internal cross-linking mechanics. Large-amplitude static configurations can be described analytically, and an excellent match between the model and the observed counterbend deformation was found. This allowed a simultaneous estimation of multiple sperm flagellum material parameters, namely the cross-linking sliding resistance, the bending stiffness, and the sperm head junction compliance ratio. We further show that small variations on the empirical conditions may induce discrepancies for the evaluation of the flagellar material quantities, so that caution is required when interpreting experiments. Finally, our analysis demonstrates that the counterbend emerges as a fundamental property of sliding resistance in cross-linked filamentous polymer bundles, which also suggests that cross-linking proteins may contribute to the regulation of the flagellar waveform in swimming sperm via counterbend mechanics

    Spin dependent scattering of a domain-wall of controlled size

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    Magnetoresistance measurements in the CPP geometry have been performed on single electrodeposited Co nanowires exchange biased on one side by a sputtered amorphous GdCo layer. This geometry allows the stabilization of a single domain wall in the Co wire, the thickness of which can be controlled by an external magnetic field. Comparing magnetization, resistivity, and magnetoresistance studies of single Co nanowires, of GdCo layers, and of the coupled system, gives evidence for an additional contribution to the magnetoresistance when the domain wall is compressed by a magnetic field. This contribution is interpreted as the spin dependent scattering within the domain wall when the wall thickness becomes smaller than the spin diffusion length.Comment: 9 pages, 13 figure
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