EF+EX Forest Algebras

We examine languages of unranked forests definable using the temporal operators EF and EX. We characterize the languages definable in this logic, and various fragments thereof, using the syntactic forest algebras introduced by Bojanczyk and Walukiewicz. Our algebraic characterizations yield efficient algorithms for deciding when a given language of forests is definable in this logic. The proofs are based on understanding the wreath product closures of a few small algebras, for which we introduce a general ideal theory for forest algebras. This combines ideas from the work of Bojanczyk and Walukiewicz for the analogous logics on binary trees and from early work of Stiffler on wreath product of finite semigroups

Diagnosis of antiphospholipid syndrome in routine clinical practice.

The updated international consensus criteria for definite antiphospholipid syndrome (APS) are useful for scientific clinical studies. However, there remains a need for diagnostic criteria for routine clinical use. We audited the results of routine antiphospholipid antibodies (aPLs) in a cohort of 193 consecutive patients with aPL positivity-based testing for lupus anticoagulant (LA), IgG and IgM anticardiolipin (aCL) and anti-ß(2)glycoprotein-1 antibodies (aß(2)GPI). Medium/high-titre aCL/aβ(2)GPI was defined as >99th percentile. Low-titre aCL/aβ(2)GPI positivity (>95(th )< 99(th) percentile) was considered positive for obstetric but not for thrombotic APS. One hundred of the 145 patients fulfilled both clinical and laboratory criteria for definite APS. Twenty-six women with purely obstetric APS had persistent low-titre aCL and/or aβ(2)GPI. With the inclusion of these patients, 126 of the 145 patients were considered to have APS. Sixty-seven out of 126 patients were LA-negative, of whom 12 had aCL only, 37 had aβ(2)GPI only and 18 positive were for both. The omission of aCL or aβ(2)GPI testing from investigation of APS would have led to a failure to diagnose APS in 9.5% and 29.4% of patients, respectively. Our data suggest that LA, aCL and aβ(2)GPI testing are all required for the accurate diagnosis of APS and that low-titre antibodies should be included in the diagnosis of obstetric APS

Evidence regarding clinical use of microvolt T-wave alternans [Accuracy of microvolt T-wave alternans testing]

Background: Microvolt T-wave alternans (MTWA) testing in many studies has proven to be a highly accurate predictor of ventricular tachyarrhythmic events (VTEs) in patients with risk factors for sudden cardiac death (SCD) but without a prior history of sustained VTEs (primary prevention patients). In some recent studies involving primary prevention patients with prophylactically implanted cardioverter-defibrillators (ICDs), MTWA has not performed as well. Objective: This study examined the hypothesis that MTWA is an accurate predictor of VTEs in primary prevention patients without implanted ICDs, but not of appropriate ICD therapy in such patients with implanted ICDs. Methods: This study identified prospective clinical trials evaluating MTWA measured using the spectral analytic method in primary prevention populations and analyzed studies in which: (1) few patients had implanted ICDs and as a result none or a small fraction (≤15%) of the reported end point VTEs were appropriate ICD therapies (low ICD group), or (2) many of the patients had implanted ICDs and the majority of the reported end point VTEs were appropriate ICD therapies (high ICD group). Results: In the low ICD group comprising 3,682 patients, the hazard ratio associated with a nonnegative versus negative MTWA test was 13.6 (95% confidence interval [CI] 8.5 to 30.4) and the annual event rate among the MTWA-negative patients was 0.3% (95% CI: 0.1% to 0.5%). In contrast, in the high ICD group comprising 2,234 patients, the hazard ratio was only 1.6 (95% CI: 1.2 to 2.1) and the annual event rate among the MTWA-negative patients was elevated to 5.4% (95% CI: 4.1% to 6.7%). In support of these findings, we analyzed published data from the Multicenter Automatic Defibrillator Trial II (MADIT II) and Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) trials and determined that in those trials only 32% of patients who received appropriate ICD therapy averted an SCD. Conclusion: This study found that MTWA testing using the spectral analytic method provides an accurate means of predicting VTEs in primary prevention patients without implanted ICDs; in particular, the event rate is very low among such patients with a negative MTWA test. In prospective trials of ICD therapy, the number of patients receiving appropriate ICD therapy greatly exceeds the number of patients who avert SCD as a result of ICD therapy. In trials involving patients with implanted ICDs, these excess appropriate ICD therapies seem to distribute randomly between MTWA-negative and MTWA-nonnegative patients, obscuring the predictive accuracy of MTWA for SCD. Appropriate ICD therapy is an unreliable surrogate end point for SCD

Charge Transfer in Partition Theory

The recently proposed Partition Theory (PT) [J.Phys.Chem.A 111, 2229 (2007)] is illustrated on a simple one-dimensional model of a heteronuclear diatomic molecule. It is shown that a sharp definition for the charge of molecular fragments emerges from PT, and that the ensuing population analysis can be used to study how charge redistributes during dissociation and the implications of that redistribution for the dipole moment. Interpreting small differences between the isolated parts' ionization potentials as due to environmental inhomogeneities, we gain insight into how electron localization takes place in H2+ as the molecule dissociates. Furthermore, by studying the preservation of the shapes of the parts as different parameters of the model are varied, we address the issue of transferability of the parts. We find good transferability within the chemically meaningful parameter regime, raising hopes that PT will prove useful in chemical applications.Comment: 12 pages, 16 figure

Diffuse radio emission in the merging cluster MACS J0717.5+3745: the discovery of the most powerful radio halo

Hierarchical models of structure formation predict that galaxy clusters grow via mergers of smaller clusters and galaxy groups, as well as through continuous accretion of gas. MACS J0717.5+3745 is an X-ray luminous and complex merging cluster, located at a redshift of 0.55. Here we present Giant Metrewave Radio Telescope (GMRT) radio observations at 610 MHz of this cluster. The main aim of the observations is to search for diffuse radio emission within the galaxy cluster MACS J0717.5+3745 related to the ongoing merger. These GMRT observations are complemented by Very Large Array (VLA) archival observations at 1.4, 4.9 and 8.5 GHz. We have discovered a radio halo in the cluster MACS J0717.5+3745 with a size of about 1.2 Mpc. The radio power P_1.4 GHz is 5 x 10^25 W/Hz, which makes it the most powerful radio halo known till date. A 700 kpc radio structure, which we classify as a radio relic, is located in between the merging substructures of the system. The location of this relic roughly coincides with regions of the intra-cluster medium (ICM) that have a significant enhancement in temperature as shown by Chandra. The major axis of the relic is also roughly perpendicular to the merger axis. This shows that the relic might be the result of a merger-related shock wave, where particles are accelerated via the diffuse shock acceleration (DSA) mechanism. Alternatively, the relic might trace an accretion shock of a large-scale galaxy filament to the south-west. The global spectral index of radio emission within the cluster is found to be -1.24 +/-0.05 between 4.9 GHz and 610 MHz. We derive a value of 5.8 microGauss for the equipartition magnetic field strength at the location of the radio halo. [abridged].Comment: 8 pages, 9 figures, accepted for publication in A&A on August 3, 200

Numerical Modeling Of Hohlraum Radiation Conditions: Spatial And Spectral Variations Due To Sample Position, Beam Pointing, And Hohlraum Geometry

View-factor simulations are presented of the spatially varying radiation conditions inside double-ended gold Hohlraums and single-ended gold Hohlraums (\u27\u27 halfraums \u27\u27) used in inertial confinement fusion and high-energy density physics experiments [J. Lindl, Phys. Plasmas 11, 339 (2004); M. D. Rosen, Phys. Plasmas 3, 1803 (1996)]. It is shown that in many circumstances, the common assumption that the Hohlraum \u27\u27 drive \u27\u27 can be characterized by a single temperature is too simplistic. Specifically, the radiation conditions seen by an experimental package can differ significantly from the wall reemission measured through diagnostic holes or laser entrance holes (LEHs) by absolutely calibrated detectors. Furthermore, even in situations where the radiation temperature is roughly the same for diagnostics and experimental packages, or for packages at different locations, the spectral energy distributions can vary significantly, due to the differing fractions of reemitting wall, laser hot spots, and LEHs seen from different locations. We find that the spatial variation of temperature and especially the differences between what diagnostics looking in the LEH measure versus the radiation temperature on wall-mounted experimental packages are generally greater for double-ended Hohlraums than for halfraums. View-factor simulations can also be used to explore experimental variables (halfraum length and geometry, sample position, and beam pointing) that can be adjusted in order to, for example, maximize the radiation flux onto a sample, or other package. In this vein, simulations of Hohlraums and halfraums with LEH shields are also presented. (c) 2005 American Institute of Physics

Extrinsic models for the dielectric response of CaCu{3}Ti{4}O{12}

The large, temperature-independent, low-frequency dielectric constant recently observed in single-crystal CaCu{3}Ti{4}O{12} is most plausibly interpreted as arising from spatial inhomogenities of its local dielectric response. Probable sources of inhomogeneity are the various domain boundaries endemic in such materials: twin, Ca-ordering, and antiphase boundaries. The material in and neighboring such boundaries can be insulating or conducting. We construct a decision tree for the resulting six possible morphologies, and derive or present expressions for the dielectric constant for models of each morphology. We conclude that all six morphologies can yield dielectric behavior consistent with observations and suggest further experiments to distinguish among them.Comment: 9 pages, with 1 postscript figure embedded. Uses REVTEX and epsf macros. Also available at http://www.physics.rutgers.edu/~dhv/preprints/mc_ext/index.htm

Optimal Iris Fuzzy Sketches

Fuzzy sketches, introduced as a link between biometry and cryptography, are a way of handling biometric data matching as an error correction issue. We focus here on iris biometrics and look for the best error-correcting code in that respect. We show that two-dimensional iterative min-sum decoding leads to results near the theoretical limits. In particular, we experiment our techniques on the Iris Challenge Evaluation (ICE) database and validate our findings.Comment: 9 pages. Submitted to the IEEE Conference on Biometrics: Theory, Applications and Systems, 2007 Washington D