55,287 research outputs found
Classes of confining gauge field configurations
We present a numerical method to compute path integrals in effective SU(2)
Yang-Mills theories. The basic idea is to approximate the Yang-Mills path
integral by summing over all gauge field configurations, which can be
represented as a linear superposition of a small number of localized building
blocks. With a suitable choice of building blocks many essential features of
SU(2) Yang-Mills theory can be reproduced, particularly confinement. The
analysis of our results leads to the conclusion that topological charge as well
as extended structures are essential elements of confining gauge field
configurations.Comment: 18 pages, 16 figures, several sections adde
Three-dimensional pantograph for use in hazardous environments
Material measurement device is used with radioactive probes which can be approached only to distance of 3 feet. Tracer-following unit is capable of precisely controlled movement in X-Y-Z planes. Pantograph is usable in industrial processes involving chemical corrosives, poisons, and bacteriological hazards, as well as nuclear applications
Axial compressor middle stage secondary flow study
This report describes an experimental investigation of the secondary flow within and aft of an axial compressor model with thick endwall boundary layers. The objective of the study was to obtain detailed aerodynamic and trace gas concentration traverse data aft of a well documented isolated rotor for the ultimate purpose of improving the design phases of compressor development based on an improved physical understanding of secondary flow. It was determined from the flow visualization, aerodynamic, and trace gas concentration results that the relative unloading of the midspan region of the airfoil inhibitied a fullspan separation at high loading preventing the massive radial displacement of the hub corner stall to the tip. Radial distribution of high and low total pressure fluid influenced the magnitude of the spanwise distribution of loss, such that, there was a general decreases in loss near the hub to the extent that for the least loaded case a negative loss (increase in total pressure) was observed. The ability to determine the spanwise distribution of blockage was demonstrated. Large blockage was present in the endwall regions due to the corner stall and tip leakage with little blockage in the core flow region. Hub blockage was found to increase rapidly with loading
Comment on "Regularizing capacity of metabolic networks"
In a recent paper, Marr, Muller-Linow and Hutt [Phys. Rev. E 75, 041917
(2007)] investigate an artificial dynamic system on metabolic networks. They
find a less complex time evolution of this dynamic system in real networks,
compared to networks of reference models. The authors argue that this suggests
that metabolic network structure is a major factor behind the stability of
biochemical steady states. We reanalyze the same kind of data using a dynamic
system modeling actual reaction kinetics. The conclusions about stability, from
our analysis, are inconsistent with those of Marr et al. We argue that this
issue calls for a more detailed type of modeling
Reactivation of the mitosis-promoting factor in postmitotic cardiomyocytes
Cardiomyocytes cease to divide shortly after birth and an irreversible cell cycle arrest is evident accompanied by the downregulation of cyclin-dependent kinase activities. To get a better understanding of the cardiac cell cycle and its regulation, the effect of functional recovery of the mitosis-promoting factor (MPF) consisting of cyclin B1 and the cyclin-dependent kinase Cdc2 was assessed in primary cultures of postmitotic ventricular adult rat cardiomyocytes ( ARC). Gene transfer into ARC was achieved using the adenovirus-enhanced transferrinfection system that was characterized by the absence of cytotoxic events. Simultaneous ectopic expression of wild-type versions of cyclin B1 and Cdc2 was sufficient to induce MPF activity. Reestablished MPF resulted in a mitotic phenotype, marked by an abnormal condensation of the nuclei, histone H3 phosphorylation and variable degree of decay of the contractile apparatus. Although a complete cell division was not observed, the results provided conclusive evidence that cell cycle-related events in postmitotic cardiomyocytes could be triggered by genetic intervention downstream of the G1/S checkpoint. This will be of importance to design novel strategies to overcome the proliferation arrest in adult cardiomyocytes
Heat transfer in rotating serpentine passages with trips skewed to the flow
Experiments were conducted to determine the effects of buoyancy and Coriolis forces on heat transfer in turbine blade internal coolant passages. The experiments were conducted with a large scale, multi-pass, heat transfer model with both radially inward and outward flow. Trip strips, skewed at 45 deg to the flow direction, were machined on the leading and trailing surfaces of the radial coolant passages. An analysis of the governing flow equations showed that four parameters influence the heat transfer in rotating passages: coolant-to-wall temperature, rotation number, Reynolds number, and radius-to-passage hydraulic diameter ratio. The first three of these four parameters were varied over ranges which are typical of advanced gas turbine engine operating conditions. Results were correlated and compared to previous results from similar stationary and rotating models with smooth walls and with trip strips normal to the flow direction. The heat transfer coefficients on surfaces, where the heat transfer decreased with rotation and buoyancy, decreased to as low as 40 percent of the value without rotation. However, the maximum values of the heat transfer coefficients with high rotation were only slightly above the highest levels previously obtained with the smooth wall models. It was concluded that (1) both Coriolis and buoyancy effects must be considered in turbine blade cooling designs with trip strips, (2) the effects of rotation are markedly different depending upon the flow direction, and (3) the heat transfer with skewed trip strips is less sensitive to buoyancy than the heat transfer in models with either smooth or normal trips. Therefore, skewed trip strips rather than normal trip strips are recommended and geometry-specific tests are required for accurate design information
Heat transfer in rotating serpentine passages with selected model orientation for smooth or skewed trip walls
Experiments were conducted to determine the effects of model orientation as well as buoyancy and Coriolis forces on heat transfer in turbine blade internal coolant passages. Turbine blades have internal coolant passage surfaces at the leading and trailing edges of the airfoil with surfaces at angles which are as large as +/- 50 to 60 degrees to the axis of rotation. Most of the previously-presented, multiple-passage, rotating heat transfer experiments have focused on radial passages aligned with the axis of rotation. Results from serpentine passages with orientations 0 and 45 degrees to the axis of rotation which simulate the coolant passages for the mid chord and trailing edge regions of the rotating airfoil are compared. The experiments were conducted with rotation in both directions to simulate serpentine coolant passages with the rearward flow of coolant or with the forward flow of coolant. The experiments were conducted for passages with smooth surfaces and with 45 degree trips adjacent to airfoil surfaces for the radial portion of the serpentine passages. At a typical flow condition, the heat transfer on the leading surfaces for flow outward in the first passage with smooth walls was twice as much for the model at 45 degrees compared to the model at 0 degrees. However, the differences for the other passages and with trips were less. In addition, the effects of buoyancy and Coriolis forces on heat transfer in the rotating passage were decreased with the model at 45 degrees, compared to the results at 0 degrees. The heat transfer in the turn regions and immediately downstream of the turns in the second passage with flow inward and in the third passage with flow outward was also a function of model orientation with differences as large as 40 to 50 percent occurring between the model orientations with forward flow and rearward flow of coolant
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