12,092 research outputs found
Theoretical investigation of the dynamic electronic response of a quantum dot driven by time-dependent voltage
We present a comprehensive theoretical investigation on the dynamic
electronic response of a noninteracting quantum dot system to various forms of
time-dependent voltage applied to the single contact lead. Numerical
simulations are carried out by implementing a recently developed hierarchical
equations of motion formalism [J. Chem. Phys. 128, 234703 (2008)], which is
formally exact for a fermionic system interacting with grand canonical
fermionic reservoirs, in the presence of arbitrary time-dependent applied
chemical potentials. The dynamical characteristics of the transient transport
current evaluated in both linear and nonlinear response regimes are analyzed,
and the equivalent classic circuit corresponding to the coupled dot-lead system
is also discussed
Exact dynamics of dissipative electronic systems and quantum transport: Hierarchical equations of motion approach
A quantum dissipation theory is formulated in terms of hierarchically coupled
equations of motion for an arbitrary electronic system coupled with grand
canonical Fermion bath ensembles. The theoretical construction starts with the
second--quantization influence functional in path integral formalism, in which
the Fermion creation and annihilation operators are represented by Grassmann
variables. Time--derivatives on influence functionals are then performed in a
hierarchical manner, on the basis of calculus--on--path--integral algorithm.
Both the multiple--frequency--dispersion and the non-Markovian reservoir
parametrization schemes are considered for the desired hierarchy construction.
The resulting formalism is in principle exact, applicable to interacting
systems, with arbitrary time-dependent external fields. It renders an exact
tool to evaluate various transient and stationary quantum transport properties
of many-electron systems. At the second--tier truncation level the present
theory recovers the real--time diagrammatic formalism developed by Sch\"{o}n
and coworkers. For a single-particle system, the hierarchical formalism
terminates at the second tier exactly, and the Landuer--B\"{u}ttiker's
transport current expression is readily recovered.Comment: The new versio
On determination of the geometric cosmological constant from the OPERA experiment of superluminal neutrinos
The recent OPERA experiment of superluminal neutrinos has deep consequences
in cosmology. In cosmology a fundamental constant is the cosmological constant.
From observations one can estimate the effective cosmological constant
which is the sum of the quantum zero point energy
and the geometric cosmological constant . The
OPERA experiment can be applied to determine the geometric cosmological
constant . It is the first time to distinguish the contributions of
and from each other by experiment. The
determination is based on an explanation of the OPERA experiment in the
framework of Special Relativity with de Sitter space-time symmetry.Comment: 7 pages, no figure
Interdimensional degeneracies for a quantum -body system in dimensions
Complete spectrum of exact interdimensional degeneracies for a quantum
-body system in -dimensions is presented by the method of generalized
spherical harmonic polynomials. In an -body system all the states with
angular momentum in dimensions are degenerate where
and are given and is an arbitrary integer if the representation
exists for the SO() group and . There is an
exceptional interdimensional degeneracy for an -body system between the
state with zero angular momentum in dimensions and the state with zero
angular momentum in dimensions.Comment: 8 pages, no figure, RevTex, Accepted by EuroPhys.Let
Release of glutamate and CGRP from trigeminal ganglion neurons: Role of calcium channels and 5-HT1 receptor signaling
<p>Abstract</p> <p>Background</p> <p>The aberrant release of the neurotransmitters, glutamate and calcitonin-gene related peptide (CGRP), from trigeminal neurons has been implicated in migraine. The voltage-gated P/Q-type calcium channel has a critical role in controlling neurotransmitter release and has been linked to Familial Hemiplegic Migraine. Therefore, we examined the importance of voltage-dependent calcium channels in controlling release of glutamate and CGRP from trigeminal ganglion neurons isolated from male and female rats and grown in culture. Serotonergic pathways are likely involved in migraine, as triptans, a class of 5-HT<sub>1 </sub>receptor agonists, are effective in the treatment of migraine and their effectiveness may be due to inhibiting neurotransmitter release from trigeminal neurons. We also studied the effect of serotonin receptor activation on release of glutamate and CGRP from trigeminal neurons grown in culture.</p> <p>Results</p> <p>P/Q-, N- and L-type channels each mediate a significant fraction of potassium-stimulated release of glutamate and CGRP. We determined that 5-HT significantly inhibits potassium-stimulated release of both glutamate and CGRP. Serotonergic inhibition of both CGRP and glutamate release can be blocked by pertussis toxin and NAS-181, a 5-HT<sub>1B/1D </sub>antagonist. Stimulated release of CGRP is unaffected by Y-25130, a 5-HT<sub>3 </sub>antagonist and SB 200646, a 5-HT<sub>2B/2C </sub>antagonist.</p> <p>Conclusion</p> <p>These data suggest that release of both glutamate and CGRP from trigeminal neurons is controlled by calcium channels and modulated by 5-HT signaling in a pertussis-toxin dependent manner and probably via 5-HT<sub>1 </sub>receptor signaling. This is the first characterization of glutamate release from trigeminal neurons grown in culture.</p
Standard model plethystics
We study the vacuum geometry prescribed by the gauge invariant operators of the minimal supersymmetric standard model via the plethystic program. This is achieved by using several tricks to perform the highly computationally challenging Molien-Weyl integral, from which we extract the Hilbert series, encoding the invariants of the geometry at all degrees. The fully refined Hilbert series is presented as the explicit sum of 1422 rational functions. We found a good choice of weights to unrefine the Hilbert series into a rational function of a single variable, from which we can read off the dimension and the degree of the vacuum moduli space of the minimal supersymmetric standard model gauge invariants. All data in Mathematica format are also presented
Modeling airport capacity choice with real options
This study analyzes optimal choice of the airport capacity to invest immediately (the prior capacity) and the size of real option to acquire for possible future expansion. Facing demand uncertainty, an airport first chooses its prior capacity and real option, and then later chooses its final capacity and airport charge once demand is observed. Our analytical results show that if demand uncertainty is low and capacity and real option costs are relatively high, an airport will not acquire a real option. Otherwise, an airport can use a real option to improve its expected profit or social welfare. Both the magnitude of profit or welfare gain and the optimal size of the real option increase with demand uncertainty. A higher real option cost leads to a larger prior capacity and smaller real option, whereas a higher capital cost leads to lower prior capacity. A profit-maximizing airport would choose a smaller prior capacity and real option than a welfare-maximizing airport. Competition in the airline market promotes airport capacity investments and the adoption of real options by profit-maximizing airports, whereas airport commercial services increase prior capacity but not real option
Variation of the Fine-Structure Constant from the de Sitter Invariant Special Relativity
There are obvious discrepancies among various experimental constraints on the
variation of the fine-structure constant, . We attempt to discuss the
issue in the framework of de Sitter invariant Special Relativity () and to present a possible solution to the disagreement. In
addition, on the basis of the observational data and the discussions presented
in this Letter, we derive a rough theoretical estimate of the radius of the
Universe.Comment: 8 pages, no figure
Antiviral treatment alters the frequency of activating and inhibitory receptor-expressing natural killer cells in chronic Hepatitis B virus infected patients
Natural killer (NK) cells play a critical role in innate antiviral immunity, but little is known about the impact of antiviral therapy on the frequency of NK cell subsets. To this aim, we performed this longitudinal study to examine the dynamic changes of the frequency of different subsets of NK cells in CHB patients after initiation of tenofovir or adefovir therapy. We found that NK cell numbers and subset distribution differ between CHB patients and normal subjects; furthermore, the association was found between ALT level and CD158b+ NK cell in HBV patients. In tenofovir group, the frequency of NK cells increased during the treatment accompanied by downregulated expression of NKG2A and KIR2DL3. In adefovir group, NK cell numbers did not differ during the treatment, but also accompanied by downregulated expression of NKG2A and KIR2DL3. Our results demonstrate that treatment with tenofovir leads to viral load reduction, and correlated with NK cell frequencies in peripheral blood of chronic hepatitis B virus infection. In addition, treatments with both tenofovir and adefovir in chronic HBV infected patients induce a decrease of the frequency of inhibitory receptor+ NK cells, which may account for the partial restoration of the function of NK cells in peripheral blood following treatment
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