66 research outputs found

    Local versus nonlocal αα\alpha\alpha interactions in 3α3\alpha description of 12^{12}C

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    Local αα\alpha \alpha potentials fail to describe 12^{12}C as a 3α3\alpha system. Nonlocal αα\alpha \alpha potentials that renormalize the energy-dependent kernel of the resonating group method allow interpreting simultaneously the ground state and 02+0^+_2 resonance of 12^{12}C as 3α3\alpha states. A comparison with fully microscopic calculations provides a measure of the importance of three-cluster exchanges in those states.Comment: The tar.gz file has 1 tex file and 1 eps fil

    Global-Vector Representation of the Angular Motion of Few-Particle Systems II

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    The angular motion of a few-body system is described with global vectors which depend on the positions of the particles. The previous study using a single global vector is extended to make it possible to describe both natural and unnatural parity states. Numerical examples include three- and four-nucleon systems interacting via nucleon-nucleon potentials of AV8 type and a 3α\alpha system with a nonlocal αα\alpha\alpha potential. The results using the explicitly correlated Gaussian basis with the global vectors are shown to be in good agreement with those of other methods. A unique role of the unnatural parity component, caused by the tensor force, is clarified in the 01−0^-_1 state of 4^4He. Two-particle correlation function is calculated in the coordinate and momentum spaces to show different characteristics of the interactions employed.Comment: 39 pages, 4 figure

    Systematic Review of Potential Health Risks Posed by Pharmaceutical, Occupational and Consumer Exposures to Metallic and Nanoscale Aluminum, Aluminum Oxides, Aluminum Hydroxide and Its Soluble Salts

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    Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); it is also present in ambient and occupational airborne particulates. Existing data underscore the importance of Al physical and chemical forms in relation to its uptake, accumulation, and systemic bioavailability. The present review represents a systematic examination of the peer-reviewed literature on the adverse health effects of Al materials published since a previous critical evaluation compiled by Krewski et al. (2007). Challenges encountered in carrying out the present review reflected the experimental use of different physical and chemical Al forms, different routes of administration, and different target organs in relation to the magnitude, frequency, and duration of exposure. Wide variations in diet can result in Al intakes that are often higher than the World Health Organization provisional tolerable weekly intake (PTWI), which is based on studies with Al citrate. Comparing daily dietary Al exposures on the basis of “total Al”assumes that gastrointestinal bioavailability for all dietary Al forms is equivalent to that for Al citrate, an approach that requires validation. Current occupational exposure limits (OELs) for identical Al substances vary as much as 15-fold. The toxicity of different Al forms depends in large measure on their physical behavior and relative solubility in water. The toxicity of soluble Al forms depends upon the delivered dose of Al+ 3 to target tissues. Trivalent Al reacts with water to produce bidentate superoxide coordination spheres [Al(O2)(H2O4)+ 2 and Al(H2O)6 + 3] that after complexation with O2‱−, generate Al superoxides [Al(O2‱)](H2O5)]+ 2. Semireduced AlO2‱ radicals deplete mitochondrial Fe and promote generation of H2O2, O2 ‱ − and OH‱. Thus, it is the Al+ 3-induced formation of oxygen radicals that accounts for the oxidative damage that leads to intrinsic apoptosis. In contrast, the toxicity of the insoluble Al oxides depends primarily on their behavior as particulates. Aluminum has been held responsible for human morbidity and mortality, but there is no consistent and convincing evidence to associate the Al found in food and drinking water at the doses and chemical forms presently consumed by people living in North America and Western Europe with increased risk for Alzheimer\u27s disease (AD). Neither is there clear evidence to show use of Al-containing underarm antiperspirants or cosmetics increases the risk of AD or breast cancer. Metallic Al, its oxides, and common Al salts have not been shown to be either genotoxic or carcinogenic. Aluminum exposures during neonatal and pediatric parenteral nutrition (PN) can impair bone mineralization and delay neurological development. Adverse effects to vaccines with Al adjuvants have occurred; however, recent controlled trials found that the immunologic response to certain vaccines with Al adjuvants was no greater, and in some cases less than, that after identical vaccination without Al adjuvants. The scientific literature on the adverse health effects of Al is extensive. Health risk assessments for Al must take into account individual co-factors (e.g., age, renal function, diet, gastric pH). Conclusions from the current review point to the need for refinement of the PTWI, reduction of Al contamination in PN solutions, justification for routine addition of Al to vaccines, and harmonization of OELs for Al substances

    Appareillage et méthodologie d'étude des surfaces de GaAs en cours de croissance en épitaxie phase vapeur

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    La caractĂ©risation, Ă  l'Ă©chelle microscopique, de l'interface solide-vapeur au cours d'une rĂ©action d'Ă©pitaxie en phase vapeur apporterait des Ă©lĂ©ments essentiels Ă  la comprĂ©hension des mĂ©canismes de croissance cristalline. On dĂ©crit ici un appareillage capable d'accĂ©der Ă  l'interface de croissance in vivo. Pour cela, un rĂ©acteur d'Ă©pitaxie vapeur a Ă©tĂ© amĂ©nagĂ© pour permettre des mesures d'ellipsomĂ©trie. Pour complĂ©ter les informations obtenues, un systĂšme de sas permet un transfert direct dans un bĂąti ultra-vide oĂč on examine la surface en diffraction Ă©lectronique LEED et RHEED et en spectromĂ©trie AUGER. On illustre le fonctionnement du systĂšme sur le cas de couches Ă©pitaxiales de GaAs (100) prĂ©parĂ©es dans le systĂšme H2-GaAs-AsCl 3

    Susceptibility to measles, mumps, and rubella in 5-year-old children in Flanders, Belgium33992

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    The second dose of an MMR vaccine is a catch up for persons who did not receive the first dose or for primary vaccine failures. Catch up doses can be scheduled according to convenience into the program of the country. The second MMR dose is often administered at the age of 5 years, before school entry. Some countries chose to implement the second dose at the age of 10-13 years, as is the case for Belgium. The here presented long-term follow-up of a cohort of children, set up originally to analyze maternal antibodies against vaccine preventable diseases, offers a unique opportunity to evaluate ad interim the current long-interval MMR vaccination schedule in Belgium. After 1 MMR dose at 12 months of age, rubella immunity is almost intact at 5 years of age (94.5 % is seropositive), measles seropositivity scores 86.8 %, and mumps 32 %, measured with ELISA. A seroneutralization (SN) test for mumps antibodies reveals much higher seropositivity rates (88 %). Using a regression model on the log (IgG) titer for all antigens, no influence was found from any of the studied variables, except for girls who had a significantly higher rubella IgG titer (p = 0.002) compared to boys. CONCLUSION: The data show considerable susceptibility to mumps and measles in 5-year-old children, confirming a previously conducted seroprevalence study (2006). Both advantages and disadvantages of shortening or enlarging the vaccine schedule are discussed</p
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