491 research outputs found

    Note on Moufang-Noether currents

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    The derivative Noether currents generated by continuous Moufang tranformations are constructed and their equal-time commutators are found. The corresponding charge algebra turns out to be a birepresentation of the tangent Mal'ltsev algebra of an analytic Moufang loop.Comment: LaTeX2e, 6 pages, no figures, presented on "The XVth International Colloquium on Integrable Systems and Quantum Symmetries, Prague, 15-17 June, 2006

    Retention of mouth-to-mouth, mouth-to-mask and mouth-to-face shield ventilation

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    Background: Retention of mouth-to-mouth, mouth-to-mask and mouth-to-face shield ventilation techniques is poorly understood.Methods: A prospective randomised clinical trial was undertaken in January 2004 in 70 candidates randomly assigned to training in mouth-to-mouth, mouth-to-mask or mouth-to-face shield ventilation. Each candidate was trained for 10 min, after which tidal volume, respiratory rate, minute volume, peak airway pressure and the presence or absence of stomach inflation were measured. 58 subjects were reassessed 1 year later and study parameters were recorded again. Data were analysed with ANOVA, \textgreekq2 and McNemar tests.Results: Tidal volume, minute volume, peak airway pressure, ventilation rate and stomach inflation rate increased significantly at reassessment with all ventilation techniques compared with the initial assessment. However, at reassessment, mean (SD) tidal volume (960 (446) vs 1008 (366) vs 1402 (302) ml; p<0.05), minute volume (12 (5) vs 13 (7) vs 18 (3) l/min; p<0.05), peak airway pressure (14 (8) vs 17 (13) vs 25 (8) cm H2O; p<0.05) and stomach inflation rate (63% vs 58% vs 100%; p<0.05) were significantly lower with mouth-to-mask and mouth-to-face shield ventilation than with mouth-to-mouth ventilation. The ventilation rate at reassessment did not differ significantly between the ventilation techniques.Conclusions: One year after a single episode of ventilation training, lay persons tended to hyperventilate; however, the degree of hyperventilation and resulting stomach inflation were lower when a mouth-to-mask or a face shield device was employed. Regular training is therefore required to retain ventilation skills; retention of skills may be better with ventilation devices

    Autoresuscitation (Lazarus phenomenon) after termination of cardiopulmonary resuscitation - a scoping review.

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    Autoresuscitation describes the return of spontaneous circulation after termination of resuscitation (TOR) following cardiac arrest (CA). We aimed to identify phenomena that may lead to autoresuscitation and to provide guidance to reduce the likelihood of it occurring. We conducted a literature search (Google Scholar, MEDLINE, PubMed) and a scoping review according to PRISMA-ScR guidelines of autoresuscitation cases where patients undergoing CPR recovered circulation spontaneously after TOR with the following criteria: 1) CA from any cause; 2) CPR for any length of time; 3) A point was reached when it was felt that the patient had died; 4) Staff declared the patient dead and stood back. No further interventions took place; 5) Later, vital signs were observed. 6) Vital signs were sustained for more than a few seconds, such that staff had to resume active care. Sixty-five patients with ROSC after TOR were identified in 53 articles (1982-2018), 18 (28%) made a full recovery. Almost a third made a full recovery after autoresuscitation. The following reasons for and recommendations to avoid autoresuscitation can be proposed: 1) In asystole with no reversible causes, resuscitation efforts should be continued for at least 20 min; 2) CPR should not be abandoned immediately after unsuccessful defibrillation, as transient asystole can occur after defibrillation; 3) Excessive ventilation during CPR may cause hyperinflation and should be avoided; 4) In refractory CA, resuscitation should not be terminated in the presence of any potentially-treatable cardiac rhythm; 5) After TOR, the casualty should be observed continuously and ECG monitored for at least 10 min

    ACSM Expert Consensus Statement: Injury Prevention and Exercise Performance during Cold-Weather Exercise

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    ABSTRACT: Cold injury can result from exercising at low temperatures and can impair exercise performance or cause lifelong debility or death. This consensus statement provides up-to-date information on the pathogenesis, nature, impacts, prevention, and treatment of the most common cold injuries

    Cross-Talk between Staphylococcus aureus and Other Staphylococcal Species via the agr Quorum Sensing System

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    Staphylococci are associated with both humans and animals. While most are non-pathogenic colonizers, Staphylococcus aureus is an opportunistic pathogen capable of causing severe infections. S. aureus virulence is controlled by the agr quorum sensing system responding to secreted auto-inducing peptides (AIPs) sensed by AgrC, a two component histidine kinase. agr loci are found also in other staphylococcal species and for Staphylococcus epidermidis, the encoded AIP represses expression of agr regulated virulence genes in S. aureus. In this study we aimed to better understand the interaction between staphylococci and S. aureus, and show that this interaction may eventually lead to the identification of new anti-virulence candidates to target S. aureus infections. Here we show that culture supernatants of 37 out of 52 staphylococcal isolates representing 17 different species inhibit S. aureus agr. The dog pathogen, Staphylococcus schleiferi, expressed the most potent inhibitory activity and was active against all four agr classes found in S. aureus. By employing a S. aureus strain encoding a constitutively active AIP receptor we show that the activity is mediated via agr. Subsequent cloning and heterologous expression of the S. schleiferi AIP in S. aureus demonstrated that this molecule was likely responsible for the inhibitory activity, and further proof was provided when pure synthetic S. schleiferi AIP was able to completely abolish agr induction of an S. aureus reporter strain. To assess impact on S. aureus virulence, we co-inoculated S. aureus and S. schleiferi in vivo in the Galleria mellonella wax moth larva, and found that expression of key S. aureus virulence factors was abrogated. Our data show that the S. aureus agr locus is highly responsive to other staphylococcal species suggesting that agr is an inter-species communication system. Based on these results we speculate that interactions between S. aureus and other colonizing staphylococci will significantly influence the ability of S. aureus to cause infection, and we propose that other staphylococci are potential sources of compounds that can be applied as anti-virulence therapy for combating S. aureus infections

    Draft Genome Sequences of Two Avian Pathogenic<i> Escherichia coli </i>Strains of Clinical Importance, E44 and E51

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    Avian pathogenic Escherichia coli strains have remarkable impacts on animal welfare and the production economy in the poultry industry worldwide. Here, we present the draft genomes of two isolates from chickens (E44 and E51) obtained from field outbreaks and subsequently investigated for their potential for use in autogenous vaccines for broiler breeders

    Does the autecology of core species reflect the synecology of functional groups during the assembly of vegetation in abandoned extracted peatlands?

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    The combined autecology of individual species is expected to reflect the synecology of their respective functional groups and vice versa, but this assumption has been rarely assessed. We estimated this similarity in limiting ecological filters using vegetation survey data from 64 abandoned extracted peatlands in Estonia, which form a 50-year chronosequence of secondary succession. Partial overlap was found between filters predicting the occurrence of individual core species and richness in their respective functional groups. These overlapping filters were microtopographical form (flats, margins, ditches), time since abandonment, and various properties of peat. At the functional group level, time since abandonment and habitat properties showed clear interactions with microform type. Bog species and acidophilous bilocals successfully established on flats and ditch margins when residual peat was acidic and poorly decayed, while species of fens and mineral soils preferentially established in ditches of large extraction fields, where residual peat had higher pH and higher mineral content. We also detected some effects of landscape-level (patch area and forest neighbourhood) and regional filters (continentality); however, their limiting role was inconsistent. Many ecological filters also were shared between functional groups at the species level, but the optimal levels of these filters differed between groups. We conclude that even in species-poor habitats, both the autecology of individual species and the synecology of functional groups should be considered during habitat restoration. In peatland restoration, the following management strategies are advised to direct a faster and more successful trajectory: controlling the depth of peat extraction, partial filling of ditches, introducing plant propagules and managing mineral dust pollution
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