70 research outputs found
Near-unity coupling efficiency of a quantum emitter to a photonic-crystal waveguide
A quantum emitter efficiently coupled to a nanophotonic waveguide constitutes
a promising system for the realization of single-photon transistors,
quantum-logic gates based on giant single-photon nonlinearities, and high
bit-rate deterministic single-photon sources. The key figure of merit for such
devices is the -factor, which is the probability for an emitted single
photon to be channeled into a desired waveguide mode. We report on the
experimental achievement of for a quantum dot
coupled to a photonic-crystal waveguide, corresponding to a single-emitter
cooperativity of . This constitutes a nearly ideal
photon-matter interface where the quantum dot acts effectively as a 1D
"artificial" atom, since it interacts almost exclusively with just a single
propagating optical mode. The -factor is found to be remarkably robust
to variations in position and emission wavelength of the quantum dots. Our work
demonstrates the extraordinary potential of photonic-crystal waveguides for
highly efficient single-photon generation and on-chip photon-photon
interaction
Single-photon nonlinear optics with a quantum dot in a waveguide
Strong nonlinear interactions between photons enable logic operations for
both classical and quantum-information technology. Unfortunately, nonlinear
interactions are usually feeble and therefore all-optical logic gates tend to
be inefficient. A quantum emitter deterministically coupled to a propagating
mode fundamentally changes the situation, since each photon inevitably
interacts with the emitter, and highly correlated many-photon states may be
created . Here we show that a single quantum dot in a photonic-crystal
waveguide can be utilized as a giant nonlinearity sensitive at the
single-photon level. The nonlinear response is revealed from the intensity and
quantum statistics of the scattered photons, and contains contributions from an
entangled photon-photon bound state. The quantum nonlinearity will find
immediate applications for deterministic Bell-state measurements and
single-photon transistors and paves the way to scalable waveguide-based
photonic quantum-computing architectures
Double-heterostructure cavities: from theory to design
We derive a frequency-domain-based approach for radiation (FAR) from
double-heterostructure cavity (DHC) modes. We use this to compute the quality
factors and radiation patterns of DHC modes. The semi-analytic nature of our
method enables us to provide a general relationship between the radiation
pattern of the cavity and its geometry. We use this to provide general designs
for ultrahigh quality factor DHCs with radiation patterns that are engineered
to emit vertically
Homocysteine, vitamin B12 and folate levels in premature coronary artery disease
BACKGROUND: Hyperhomocysteinemia is known as an independent risk factor of atherosclerosis, but the probable role of hyperhomocysteinemia in premature Coronary Artery Disease (CAD) is not well studied. The aim of this study was to assess the role of hyperhomocysteinemia, folate and Vitamin B12 deficiency in the development of premature CAD. METHODS: We performed an analytical case-control study on 294 individuals under 45 years (225 males and 69 females) who were admitted for selective coronary angiography to two centers in Tehran. RESULTS: After considering the exclusion criteria, a total number of 225 individuals were enrolled of which 43.1% had CAD. The mean age of participants was 39.9 +/- 4.3 years (40.1 +/- 4.2 years in males and 39.4 +/- 4.8 years in females). Compared to the control group, the level of homocysteine measured in the plasma of the male participants was significantly high (14.9 +/- 1.2 versus 20.3 +/- 1.9 micromol/lit, P = 0.01). However there was no significant difference in homocysteine level of females with and without CAD (11.8 +/- 1.3 versus 11.5 ± 1.1 micromol/lit, P = 0.87). Mean plasma level of folic acid and vitamin B12 in the study group were 6.3 +/- 0.2 and 282.5 +/- 9.1 respectively. Based on these findings, 10.7% of the study group had folate deficiency while 26.6% had Vitamin B12 deficiency. Logistic regression analysis for evaluating independent CAD risk factors showed hyperhomocysteinemia as an independent risk factor for premature CAD in males (OR = 2.54 0.95% CI 1.23 to 5.22, P = 0.01). Study for the underlying causes of hyperhomocysteinemia showed that male gender and Vitamin B12 deficiency had significant influence on incidence of hyperhomocysteinemia. CONCLUSION: We may conclude that hyperhomocysteinemia is an independent risk factor for CAD in young patients (bellow 45 years old) – especially in men -and vitamin B12 deficiency is a preventable cause of hyperhomocysteinemia
Assessment of Sialic Acid distribution in mouse epididymis
Previous studies have shown that epididymial and its secretions are critical for sperm maturation. These secretions contain many glycoconjugates with sialic acid terminal sugar. This terminal sugar by intervening in cellular interactions and masking surface receptors, has an important role in sperm maturation and protection. Moreover lectins have been employed as useful probes to detect the presence of glycoconjugates with specific sugar residues such as sialic acid. Considering the importance of sialic acid, distribution of this terminal sugar in different parts of mouse epididymis was studied by means of lectin histochemistry. For this purpose, epididymial tissue species were obtained from 15 adult male BALB/c mice. After fixation and routine laboratory process, 5 µm sections prepared from paraffin blocks. Slides were exposed to lectins with lectin-histochemistry. For this purpose, wheat germ agglutinin (WGA), specific for sialic acid, was employed. Then they assessed with light microscope. The rate of reactions in epithelial cells and spermatozoa were significantly different parts of epididyms. In this manner that, in spermatozoa, stereo cilia and luminal surface the least reactions were seen in caput, while the most reactions were seen in cauda. Epithelial cells, too, showed less reaction in caput comparing to corpus and tail of epididyms. Sialic acid has been identified in many glycoproteins secreted by epididyms and is necessary for sperm maturation. It seems that this maturation happens mostly in body and tail of epididyms during epididymial transit. Increase in sialic acid content of spermatozoa during epididymial transit is probably due to the secretion of glycoconjugates containing this component by epididymial principal and flask cells.
Keywords: Epididymis, Sialic acid, Lectin histochemistry, Mous
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