51 research outputs found
3D sedimentary architecture showing the inception of an Ice Age
Abstract: Northeast Atlantic climate shifted into the Quaternary Ice Age around 2.6 M yr ago. Until now, however, the detailed changes associated with this inception of an Ice Age have remained obscure. New high-quality three-dimensional seismic data reveal a detailed geological record of buried surfaces, landforms and sedimentary architecture over vast parts of the Norwegian North Sea. Here, we show the sequence of near-coast geological events spanning the Northeast Atlantic inception of an Ice Age. We identify the location of immediate pre-glacial fluvially derived sandy systems where rivers from the Norwegian mainland built marine deltas. The stratigraphic position of a large submarine channel, formed by enhanced meltwater from initial build-up of local glaciers, is also shown. Finally, we document the transition to full ice-sheet growth over Scandinavia from the ice sheetâs earliest position to the later pattern of debris-flow lobes reaching the present-day shelf edge
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Sweet taste pleasantness is modulated by morphine and naltrexone
Rodent models highlight the key role of Âľ-opioid receptor (MOR) signaling in palatable food consumption. In humans however, the effects of MOR stimulation on eating and food liking remain unclear. In a bidirectional psychopharmacological cross-over study, 49 healthy men underwent a sweet taste paradigm following double-blind administration of the MOR agonist morphine, placebo, and the opioid antagonist nalt rexone. We hypothesized that behaviors regulated by the endogenous MOR system would be enhanced by MOR agonism, and decreased by antagonism. The strongest drug effects were expected for the sweetest (high-calorie) sucrose solution, as reported in rodents. However, very sweet sucrose-water solutions are considered sickly and aversive by many people (called sweet dislikers). Since both sweet likers and dislikers were tested, we were able to assess whether MOR manipulations affect pleasantness ratings differently depending on both subjective and objective value. As hypothesized, MOR stimulation with morphine increased pleasantness of the sweetest of five sucrose solutions, without enhancing pleasantness of the lower-sucrose solutions. For opioid antagonism, an opposite pattern was observed for the sweetest drink only. This bidirectional effect of agonist and antagonist treatment is consistent with rodent findings that MOR manipulations most strongly affect the highest-calorie foods. Importantly, the observed drug effects on pleasantness of the sweetest drink did not differ between sweet likers and dislikers. We speculate that the MOR system promotes survival in part by increasing concordance between the objective (caloric) and subjective (hedonic) value of food stimuli, so that feeding behaviour becomes more focused on the richest food available
Automated PGP9.5 immunofluorescence staining: a valuable tool in the assessment of small fiber neuropathy?
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3D sedimentary architecture showing the inception of an Ice Age
Abstract: Northeast Atlantic climate shifted into the Quaternary Ice Age around 2.6 M yr ago. Until now, however, the detailed changes associated with this inception of an Ice Age have remained obscure. New high-quality three-dimensional seismic data reveal a detailed geological record of buried surfaces, landforms and sedimentary architecture over vast parts of the Norwegian North Sea. Here, we show the sequence of near-coast geological events spanning the Northeast Atlantic inception of an Ice Age. We identify the location of immediate pre-glacial fluvially derived sandy systems where rivers from the Norwegian mainland built marine deltas. The stratigraphic position of a large submarine channel, formed by enhanced meltwater from initial build-up of local glaciers, is also shown. Finally, we document the transition to full ice-sheet growth over Scandinavia from the ice sheetâs earliest position to the later pattern of debris-flow lobes reaching the present-day shelf edge
Reply to Discussion on âLate Cenozoic geological evolution of the northern North Sea: development of a Miocene unconformity reshaped by large-scale Pleistocene sand intrusionâ, Journal of the Geological Society
A regionally consistent 3D seismic-stratigraphic framework and age model for the Quaternary sediments of the northern North Sea
Morphology and pattern of Quaternary sedimentation in the North Sea Basin (52â62\ub0N)
How do preâexisting normal faults influence rift geometry? A comparison of adjacent basins with contrasting underlying structure on the Lofoten Margin, Norway
Late Cenozoic geological evolution of the northern North Sea: development of a Miocene unconformity reshaped by large-scale Pleistocene sand intrusion
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