15 research outputs found
Multicentric reticulohistiocytosis (MRH): case report with review of literature between 1991 and 2014 with in depth analysis of various treatment regimens and outcomes
DO PYHSICAL THERAPY MODALITIES HAVE ADDITIONAL BENEFIT OVER EXERCISE THERAPY IN THE MANAGEMENT OF ANKYLOSING SPONDYLITIS? A RANDOMIZED CONTROLLED TRIAL
15th Annual European Congress of Rheumatology (EULAR) -- JUN 11-14, 2014 -- Paris, FRANCEWOS: 00034691980409
Retrospective analysis of 41 rheumatology patients developing osteonecrosis
Annual European Congress of Rheumatology (EULAR 2006) -- JUN 21-24, 2006 -- Amsterdam, NETHERLANDSWOS: 00024937250111
Multicentric reticulohistiocytosis
WOS: A1996TV05200013PubMed ID: 8929779We describe a 42-year-old man with a five-year history of arthritis mutilans-like destructive joint changes and with a one-year history of nodules on the fingers, ears, oral mucosa, pharynx, larynx, vocal cords, some being ulcerated and haemorrhagic. He was diagnosed as having rheumatoid arthritis; however, biopsies from the nodules an the oral mucosa and ear revealed multicentric reticulohistiocytosis, The large nodule over the olecranon process, simulating a rheumatoid nodule but diagnosed as multicentric reticulohistiocytosis with biopsy; ulcerated and haemorrhagic nodules on the oral mucosa; and rapidly progressive joint destructions make our case interesting
Pregnancy outcome in our patients with systemic lupus erythematosus
Annual European Congress of Rheumatology (EULAR 2006) -- JUN 21-24, 2006 -- Amsterdam, NETHERLANDSWOS: 00024937250203
Very low dose methotrexate-induced rheumatoid nodules localized in buttocks and palmar aspects of phalanges: Case report [Kalça ve parmaklann palmar yüzlerinde lokalize ve çok düşük doz metotreksat ile ortaya çi{dotless}kan romatoid noduller]
Rheumatoid nodules are the most common extra-articular lesions. They usually occur in rheumatoid factor positive patients and indicate activity and severity of the disease. These nodules characteristically occur subcutaneously on extensor surfaces over the elbows or other bony prominences. They may be overlooked if they occur in sites other than well-known areas. We present a case with rheumatoid arthritis (RA) who developed multiple subcutaneous, histologically- proven rheumatoid nodules in both buttocks as well as on palmar aspects of phalanges after 3.5 years of very low-dose weekly methotrexate (MTX) treatment. These nodules occurred abruptly while there was not active arthritis in any joint. MTX-induced large nodules may occur even with very low doses of MTX, in atypical localizations such as both buttocks. © 2011 by Türkiye Klinikleri
Cigarette smoking in primary Sjögren's syndrome: Positive association only with ANA positivity
PubMed ID: 21445716Smoking is well known to contribute to the pathogenesis and severity of some systemic autoimmune rheumatic diseases and especially to the production of certain autoantibodies. Primary Sjögren's syndrome (pSS) is an autoimmune disease, affecting primarily the exocrine glands. It may also cause extraglandular involvement in some cases. In this study, we aimed to determine the frequency of smoking habits in our cohort of pSS patients and to investigate whether the frequencies of autoantibody positivity and extraglandular involvement were significantly different between patients with and without smoking. In this cross-sectional study, 207 patients with pSS (F/M 203/4), fulfilling the United States-European Consensus Criteria, and 602 healthy controls (F/M 534/68) were included. Patients and controls were classified into five groups: never smokers, current smokers, former smokers; ever smokers, and passive smokers. The X 2 and Kruskal-Wallis tests were used for statistical analysis; a p value of less than 0.05 was accepted as statistically significant. While the frequency of current smokers was significantly lower in the pSS group compared with the healthy controls (11.6 vs 22.3%), the frequencies of former smokers (30.4 vs 11.8%), ever smokers (42.0 vs 34.1%), and passive smokers (47.3 vs 37.5%) were significantly higher in the pSS group compared with the healthy controls. In pSS patients, only antinuclear antibody (ANA) positivity was significantly associated with smoking habits, while there was no significant association with other autoantibodies or with the presence of extraglandular involvement. We found that in pSS patients smoking was significantly associated only with ANA positivity. Unlike the deleterious effects of smoking upon disease severity and anti-cyclic citrullinated protein (CCP) antibody production in rheumatoid arthritis, we could not find any association of smoking with extraglandular involvement and/or anti-Ro/anti-La antibody positivity in pSS. These results are indeed in line with the limited number of previous studies reported in the literature. Further studies with higher numbers of pSS patients are required to confirm the seemingly negative association of smoking with pSS. © Japan College of Rheumatology 2011
Two siblings with juvenile hyaline fibromatosis: Case reports and review of the literature
WOS: 000081093600013PubMed ID: 11206353In this paper, we describe two siblings with Juvenile Hyaline Fibromatosis (JE-IF) who were diagnosed at the age of 34 and 29 years respectively. JHF is a very congenital disease, mainly diagnosed, in the first few years of life, with less than 40 published cases in literature. All the main clinical features of this syndrome, which may be summarised as multiple subcutaneous rumours, marked gingival hypertrophy, flexion contractures and osteolytic lesions were present in both of these cases. Clinical, radiological and histological differential diagnosis of JHF were made. Recent information about histopathology, treatment and prognosis of JHF was also reviewed