Community based trial of home blood pressure monitoring with nurse-led telephone support in patients with stroke or transient ischaemic attack recently discharged from hospital.

BACKGROUND: High blood pressure in patients with stroke increases the risk of recurrence but management in the community is often inadequate. Home blood pressure monitoring may increase patients' involvement in their care, increase compliance, and reduce the need for patients to attend their General Practitioner if blood pressure is adequately controlled. However the value of home monitoring to improve blood pressure control is unclear. In particular its use has not been evaluated in stroke patients in whom neurological and cognitive ability may present unique challenges. DESIGN: Community based randomised trial with follow up after 12 months. PARTICIPANTS: 360 patients admitted to three South London Stroke units with stroke or transient ischaemic attack within the past 9 months will be recruited from the wards or outpatients and randomly allocated into two groups. All patients will be visited by the specialist nurse at home at baseline when she will measure their blood pressure and administer a questionnaire. These procedures will be repeated at 12 months follow up by another researcher blind as to whether the patient is in intervention or control group. INTERVENTION: INTERVENTION patients will be given a validated home blood pressure monitor and support from the specialist nurse. Control patients will continue with usual care (blood pressure monitoring by their practice). Main outcome measures in both groups after 12 months: 1. Change in systolic blood pressure.2. Cost effectiveness: Incremental cost of the intervention to the National Health Service and incremental cost per quality adjusted life year gained

A Review of Affective Design towards Video Games

AbstractOver the past decade, gaming has become a mainstream form of entertainment. It is one of the fastest growing forms of entertainment and has become a big business, easily rivaling the film industry in terms of consumer spending. However, due to the rapid growth of technology and competitiveness in the industry, game designers are increasingly faced with the challenge of making their games attractive and engaging to its intended users. Over the years, practitioners and researchers in the human-computer interaction (HCI) community have placed a lot of effort in developing processes and methods for use in interdisciplinary fields. An effective user-centered gaming interface plays an important role in the gaming industry and provides valuable contribution in the HCI practice. This is because it supports the mental communication and emotional response of its audiences that is the gamers, thus improving the interaction modes between the user and product. Hence, designing games in a manner that provides the same user experience to all players, irrespective of player motivation, experience or skill is becoming the focus of modern game research. This paper will attempt to address and review the literature on affective design elements, principles and methodologies that are suitable for the video games industry

Vertical Navigation Control Laws and Logic for the Next Generation Air Transportation System

A vertical navigation (VNAV) outer-loop control system was developed to capture and track the vertical path segments of energy-efficient trajectories that are being developed for high-density operations in the evolving Next Generation Air Transportation System (NextGen). The VNAV control system has a speed-on-elevator control mode to pitch the aircraft for tracking a calibrated airspeed (CAS) or Mach number profile and a path control mode for tracking the VNAV altitude profile. Mode control logic was developed for engagement of either the speed or path control modes. The control system will level the aircraft to prevent it from flying through a constraint altitude. A stability analysis was performed that showed that the gain and phase margins of the VNAV control system significantly exceeded the design gain and phase margins. The system performance was assessed using a six-deg-of-freedom non-linear transport aircraft simulation and the performance is illustrated with time-history plots of recorded simulation data

TUNet: A Block-online Bandwidth Extension Model based on Transformers and Self-supervised Pretraining

We introduce a block-online variant of the temporal feature-wise linear modulation (TFiLM) model to achieve bandwidth extension. The proposed architecture simplifies the UNet backbone of the TFiLM to reduce inference time and employs an efficient transformer at the bottleneck to alleviate performance degradation. We also utilize self-supervised pretraining and data augmentation to enhance the quality of bandwidth extended signals and reduce the sensitivity with respect to downsampling methods. Experiment results on the VCTK dataset show that the proposed method outperforms several recent baselines in both intrusive and non-intrusive metrics. Pretraining and filter augmentation also help stabilize and enhance the overall performance.Comment: Published as a conference paper at ICASSP 2022, 5 pages, 4 figures, 3 table

Adaptive inverse filtering of room acoustics

Equalization techniques for high order, multichannel, FIR systems are important for dereverberation of speech observed in reverberation using multiple microphones. In this case the multichannel system represents the room impulse responses (RIRs). The existence of near-common zeros in multichannel RIRs can slow down the convergence rate of adaptive inverse filtering algorithms. In this paper, the effect of common and near-common zeros on both the closed-form and the adaptive inverse filtering algorithms is studied. An adaptive shortening algorithm of room acoustics is presented based on this study. 1

Single-breathhold myocardial T2 and T2* quantification in normal volunteer subjects at 3T

Myocardial Tissue Characterization: Fat, Hemorrhage & Edema - Poster presentationIncreased B0 and B1 inhomogeneity, together with increased motion artifacts, present challenges for cardiac imaging and quantitation at 3T. This study measured myocardial T2 in normal subjects at 3T using a novel single-breathhold black-blood hybrid TSE/MESE T2 measurement protocol. The average myocardial T2 was found to be 39.6±7.4ms, with peak-to-peak variations of the measured T2 values < 5%. The results demonstrate the feasibility of myocardial T2 quantitation at 3T.published_or_final_versionThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 375

Axial and radial diffusivities as potential markers for characterization of white matter lesions and predicting lesion outcome in a neonatal rat hypoxia-ischemia model

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Cervical nodal volume for prognostication and risk stratification of patients with nasopharyngeal carcinoma, and implications on the TNM-staging system

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