An FPGA-based Design Approach for Microsatellites Telemetry Subsystem

The Tele-command and Telemetry (TT&C) subsystems are one of the vital components in satellites. Commanding, managing and data sampling from different sections of the satellite are performed through the TT&C subsystem. The telemetry and Tele-command parts of this subsystem could be implemented cooperatively with or separately from each other. Based on the satellite requirements, its mission and orbital lifetime and cost various approaches may be used in order to implement this subsystem. Furthermore, nowadays, the development of satellite subsystems based on commercial devices because of their low cost and accessibility is more attractive. However, their endurance for harsh space environment remains as a severe challenge. The Field Programmable Gate Arrays (FPGAs), one of the best-developed commercial devices, are most successfully option in this application field. Nevertheless, the system designing methodology and the reliability of the implemented system on FPGAs remain as two major concerns. In this paper designing method and implementation result of Telemetry subsystem on field programmable gate array (FPGA) is presented. The implemented subsystem successfully passed environmental test according to ECSS standard. Furthermore, flight data confirm the feasibility of the presented FPGA based design methodology

Mechanobiological modelling of tendons: Review and future opportunities

Tendons are adapted to carry large, repeated loads and are clinically important for the maintenance of musculoskeletal health in an increasing, actively ageing population, as well as in elite athletes. Tendons are known to adapt to mechanical loading. Also, their healing and disease processes are highly sensitive to mechanical load. Computational modelling approaches developed to capture this mechanobiological adaptation in tendons and other tissues have successfully addressed many important scientific and clinical issues. The aim of this review is to identify techniques and approaches that could be further developed to address tendon-related problems. Biomechanical models are identified that capture the multi-level aspects of tendon mechanics. Continuum whole tendon models, both phenomenological and microstructurally motivated, are important to estimate forces during locomotion activities. Fibril-level microstructural models are documented that can use these estimated forces to detail local mechanical parameters relevant to cell mechanotransduction. Cell-level models able to predict the response to such parameters are also described. A selection of updatable mechanobiological models is presented. These use mechanical signals, often continuum tissue level, along with rules for tissue change and have been applied successfully in many tissues to predict in vivo and in vitro outcomes. Signals mayinclude scalars derived from the stress or strain tensors, or in poroelasticity also fluid velocity, while adaptation may be represented by changes to elastic modulus, permeability, fibril density or orientation. So far, only simple analytical approaches have been applied to tendon mechanobiology. With the development of sophisticated computational mechanobiological models in parallel with reporting more quantitative data from in vivo or clinical mechanobiological studies, for example, appropriate imaging, biochemical and histological data, this field offers huge potential for future development towards clinical applications

Mechanobiological modelling of tendons: Review and future opportunities

Tendons are adapted to carry large, repeated loads and are clinically important for the maintenance of musculoskeletal health in an increasing, actively ageing population, as well as in elite athletes. Tendons are known to adapt to mechanical loading. Also, their healing and disease processes are highly sensitive to mechanical load. Computational modelling approaches developed to capture this mechanobiological adaptation in tendons and other tissues have successfully addressed many important scientific and clinical issues. The aim of this review is to identify techniques and approaches that could be further developed to address tendon-related problems. Biomechanical models are identified that capture the multi-level aspects of tendon mechanics. Continuum whole tendon models, both phenomenological and microstructurally motivated, are important to estimate forces during locomotion activities. Fibril-level microstructural models are documented that can use these estimated forces to detail local mechanical parameters relevant to cell mechanotransduction. Cell-level models able to predict the response to such parameters are also described. A selection of updatable mechanobiological models is presented. These use mechanical signals, often continuum tissue level, along with rules for tissue change and have been applied successfully in many tissues to predict in vivo and in vitro outcomes. Signals mayinclude scalars derived from the stress or strain tensors, or in poroelasticity also fluid velocity, while adaptation may be represented by changes to elastic modulus, permeability, fibril density or orientation. So far, only simple analytical approaches have been applied to tendon mechanobiology. With the development of sophisticated computational mechanobiological models in parallel with reporting more quantitative data from in vivo or clinical mechanobiological studies, for example, appropriate imaging, biochemical and histological data, this field offers huge potential for future development towards clinical applications

Multiscale Simulation of Bioreactor Design and In Vitro Conditions

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