Effect of potantiostatic waveforms on properties of electrodeposited NiFe alloy films

The influence of the deposition potentials applied in continuous and pulse waveforms on the properties of the electrodeposited NiFe alloy films have been investigated. The films were grown on (100) textured polycrystalline copper substrates. During growth, the films were characterized by recording the current-time transients. The composition of samples was determined by inductively coupled plasma atomic emission spectrometry (ICP-AES). The analysis results revealed that the Fe content in the films decreases as both the deposition potential and the film thickness increase. The X-ray patterns showed that the films have face centred cubic (fee) structure as their substrates and the (111) texture. The magnetic characteristics of films studied by a vibrating sample magnetometer (VSM) were found to vary depending on the type of the deposition (pulse or continuous) and the thickness of samples. The easy axis is in the film plane for all samples

Evaluation of in vitro

The in vitro effects of the injectable form of analgesic drugs, dexketoprofen trometamol, dexamethasone sodium phosphate, metamizole sodium, diclofenac sodium, thiocolchicoside, on the activity of purified human carbonic anhydrase I and II were evaluated. The effect of these drugs on erythrocyte hCA I and hCA II was compared to recombinant hCA I and hCA II expressed in Ecoli. IC50 values of the drugs that caused inhibition were determined by means of activity percentage diagrams. The IC50 concentrations of dexketoprofen trometamol and dexamethasone sodium phosphate on hCA I were 683 mu M and 4250 mu M and for hCA II 950 mu M and 6200 mu M respectively. Conversely, the enzyme activity was increased by diflofenac sodium. In addition, thiocolchicoside has not any affect on hCA I and hCA II. The effect of these drugs on erythrocyte hCA I and hCA II were consistent with the inhibition of recombinant enzymes