Some 3, 5-Diaryl and 1, 3, 5-Triaryl-2-Pyrazoline Derivatives

Abstract: A series of 3,5-diaryl-Δ 2 -pyrazolines (2a-h) were prepared by the reaction of 1,3-diaryl-2-propen-1-ones (1) with hydrazine hydrate and used as precursor for the preparation of 1-acetyl-2-pyrazolines (3a-d). A series of1,3,5-triaryl-2-pyrazolines (6a-h) and (7a-g) were prepared by the reaction of 1,3-diaryl-2-propen-1-ones (1) with phenyl hydrazine and/or 2,4-dinitrophenylhydrazine. Similarly, 3,5-diaryl isoxazoline derivatives (9a,b) were prepared by the 1,3-cyclocondensation of 1,3-diaryl-2-propen-1-ones (1) with hydroxylamine hydro-chloride. Also 1-carbamoyl-, and 1-thiocarbamoyl-2-pyrazoline derivatives (8a-e) and (8f-j) were synthesized. The structures of the new compounds were proved by means of their IR, 1 H-, 13 C-NMR, MS spectroscopic data and microanalysis. All the new compounds were examined for their in vitro antimicrobial activity. Some newly synthesized compounds were examined for their in vitro anticancer activity. In the present investigation, we discuss the structure-activity relationships and biological activities of these compounds

Assessment of Some Mango Species by Fruit Characters and Fingerprint

Abstract: Six local mango accessions; Zebda, Zaghloul, Gemela, Ganofia, El-Madam and ElKobbaneia were collected from private farm in Sharkia Governorate. Physical and chemical characteristics of fruits study besides of molecular characterization (as total proteins). The data showed that El-Kobbaneia fruit had the biggest fruit also El-Madam produced the smallest one. The lowest fiber percentage was clear in Ganofia fruit followed by Zebda fruit as compared with all mango fruits under study. The highest fruit Juice percentage was shown in El-Kobbaneia fruit, while Ganofia fruit had the lowest one. Also, the lowest titrable acidity was clear in Ganofia fruit, but the highest one was detected in Zebda fruit. Meanwhile, the highest total sugar was clear in Gemela fruit. However, El-Madam fruit had the lowest VC. The highest total number of variable bands (seven) was existed in Zebda species while the lowest number was presented in Ganofia species (2 bands). The percentage of polymorphism in all mango species ranged between 16.7% in both EL-Kobbaneia and Gemela species to 29.2 % in Zebda species