12 research outputs found
Effect of temperature, relative humidity and rainfall on dengue fever and leptospirosis infections in Manila, the Philippines
Galectin-9 binds IgM-BCR to regulate B cell signaling
The galectin family of secreted lectins are important regulators of immune cell function; however, their role in B cell responses is poorly understood. Here, the authors identify IgM-BCR as a ligand for galectin-9. In resting naive cells, they show that galectin-9 mediates a close association between IgM and CD22