Believing in the American Dream Sustains Negative Attitudes toward Those in Poverty

A critical lever in the fight against poverty is to improve attitudes toward those living in poverty. Attempting to understand the factors that impact these attitudes, we ask: Does believing that meritocracy exists (descriptive meritocracy) sustain negative attitudes? Using cross-sectional (N = 301) and experimental (N = 439) methods, we found that belief in the United States as a meritocracy is associated with blaming people living in poverty and predicts negative attitudes toward them. Replicating and extending these findings, we experimentally manipulated beliefs in meritocracy and blame. Weakening American Dream beliefs predicted improved attitudes toward those in poverty. Understanding the nuanced role of belief systems in attitudes toward those in poverty provides strategies for promoting more positive thoughts and feelings

Many Body Theory of Charge Transfer in Hyperthermal Atomic Scattering

We use the Newns-Anderson Hamiltonian to describe many-body electronic processes that occur when hyperthermal alkali atoms scatter off metallic surfaces. Following Brako and Newns, we expand the electronic many-body wavefunction in the number of particle-hole pairs (we keep terms up to and including a single particle-hole pair). We extend their earlier work by including level crossings, excited neutrals and negative ions. The full set of equations of motion are integrated numerically, without further approximations, to obtain the many-body amplitudes as a function of time. The velocity and work-function dependence of final state quantities such as the distribution of ion charges and excited atomic occupancies are compared with experiment. In particular, experiments that scatter alkali ions off clean Cu(001) surfaces in the energy range 5 to 1600 eV constrain the theory quantitatively. The neutralization probability of Na$^+$ ions shows a minimum at intermediate velocity in agreement with the theory. This behavior contrasts with that of K$^+$, which shows ... (7 figures, not included. Figure requests: [email protected])Comment: 43 pages, plain TeX, BUP-JBM-

CETN1 is a cancer testis antigen with expression in prostate and pancreatic cancers

Background: The Cancer Testis Antigens (CTAs) are a group of genes that are highly expressed in the normal testis and several types of cancer. Due to their restricted expression in normal adult tissues, CTAs have been attractive targets for immunotherapy and biomarker development. In this work, we discovered that Centrin 1 (CETN1) which is found in the centrosome of all eukaryotes, may be a member of this group and is highly expressed in prostate and pancreatic cancer. Three members of the centrin family of calcium binding proteins (CETN) are localized to the centrosome in all eukaryotes with CDC31 being the sole yeast homolog. CETN1 is a retrogene that probably arose from a retrotransposition of CETN2, an X-linked gene. A previous mouse study shows that CETN1 is expressed solely in the testis, while CETN2 is expressed in all organs. Results: In this work, we show that CETN1 is a new member of the growing group of CTAs. Through the mining of publicly available microarray data, we discovered that human CETN1 expression but not CETN2 or CETN3 is restricted to the testis. In fact, CETN1 is actually down-regulated in testicular malignancies compared to normal testis. Using q-PCR, CETN1 expression is shown to be highly up-regulated in cancer of the prostate and in pancreatic xenografts. Unexpectedly however, CETN1 expression was virtually absent in various cell lines until they were treated with the DNA demethylation agent 5’AZA-2’Deoxycytidine (AZA) but showed no increased expression upon incubation with Histone deacetylase inhibitor Trichostatin-A (TSA) alone. Additionally, like most CTAs, CETN1 appears to be an intrinsically disordered protein which implies that it may occupy a hub position in key protein interaction networks in cancer. Neither CETN1 nor CETN2 could compensate for loss of CDC31 expression in yeast which is analogous to published data for CETN3. Conclusions: This work suggests that CETN1 is a novel CTA with expression in cancer of the prostate and pancreas. In cell lines, the expression is probably regulated by promoter methylation, while the method of regulation in normal adult tissues remains unknown

Elektronen- und ionenspektroskopische Untersuchung inelastischer Prozesse beim Stoss von Alkali- und Edelgasionen auf Alkali-bedeckte W(110)-Oberflaechen

Available from TIB Hannover: DW 9645 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

How Social-Class Background Influences Perceptions of Political Leaders

n this research, we contribute to a nascent literature examining how cues to social class can guide voters\u27 political judgments. Drawing upon and merging a voting-cues framework with the stereotype-content model, we test predictions that, relative to those from high-class backgrounds, candidates from lower- and working-class backgrounds will be perceived to be more ideologically liberal, warmer, and will be evaluated more positively. We test these predictions across four experimental studies (NStudy1 = 200; NStudy2 = 537; NStudy3 = 352; NStudy4 = 654) employing a candidate-evaluation paradigm; participants were presented with basic candidate background information, including cues to candidate class and other demographics, and were asked to read an excerpt from a speech before providing their judgments. Findings reveal that candidates from lower- and working-class backgrounds were perceived to be more liberal and warmer than those from high-class backgrounds. Additionally, we found that lower-class candidates were generally evaluated more positively than high-class candidates, and we found some evidence for evaluations across class to be moderated by participants\u27 political ideology. These effects generally held across candidate gender and race. This work has important theoretical and practical implications offering insight into the social-class gap between the electorate and the largely elite elected policymakers

SPIN AND CHARGE FLUCTUATIONS IN METALS OBSERVED BY LIGHT SCATTERING

We review results of Raman and Brillouin scattering in metallic intermediate-valence rare-earth compounds and in heavy-fermion actinide compounds. The charge relaxation rate in valence fluctuating coumpounds is identified experimentally by phonon spectroscopy, whereas spin and electron density fluctuations in heavy fermion compounds are revealed by quasielastic scattering