The diagnostic and prognostic value of red cell distribution width in cardiovascular disease, current status and prospective

The red blood cell distribution width (RDW) is an index of the heterogeneity of circulating red blood cell size, which along with other standard complete blood count (CBC) parameters are used to identify hematological system diseases. Besides hematological disorders, several clinical studies have shown that an increased in the RDW may be associated with other diseases including acute pancreatitis, chronic kidney disease, gastrointestinal disorders, cancer, and of special interest in this review, cardiovascular disease (CVD). The diagnostic and prognostic value of RDW in different CVD (acute coronary syndrome, ischemic cerebrovascular disease, peripheral artery disease, atrial fibrillation, heart failure, and acute ischemic stroke) has been reviewed in this article, to provide an understanding how its measurement may be applied to improve the management of these conditions.Keywords: RDW, Biomarker, Cardiovascular disease

Seismogenic zones in eastern Turkey

An edited version of this paper was published by the American Geophysical Union (AGU). Copyright 2003, AGU. See also: http://www.agu.org/pubs/crossref/2003.../2003GL018023.shtml; http://atlas.geo.cornell.edu/turkey/publications/Turkelli-et-al_2003.htmA 29-station temporary broadband PASSCAL network was operated from late October 1999 to August 2001 in eastern Turkey in order to decipher the geodynamics of one of the youngest continent-continent collision zones in the world. This paper focuses on the hypocentral distribution of local earthquakes located during the operation of the network and provides new insights into the active faulting in the Anatolian plateau. A total of 1165 earthquakes were located and classified into four different categories based on the reliability of the locations as established by the data coverage. The accuracy of the locations ranked in the best two categories is estimated to be less than approximately 5 km. The results show that seismic activity in Eastern Turkey is higher than previously documented and there were no subcrustal earthquakes beneath the Arabian- Eurasian collision zone or beneath the Anatolian plateau during our deployment. This result suggests no or very little underthrusting of the Arabian plate beneath Eurasia. Our results also suggest that the North Anatolian Fault zone extends farther toward the southeast, well beyond the Karliova triple junction, and that a number of unmapped active, seismogenic faults exist in the region. We also observed a possible difference in the seismogenic thickness of the East Anatolian fault zone (EAFZ) and the North Anatolian fault zone (NAFZ)

The seismotectonics of the Marmara region (Turkey): results from a microseismic experiment

The Marmara region is an active tectonic zone characterised by the transition between the dextral strike-slip regime of the North Anatolian Fault (NAF) and the extension regime of the Aegean Sea. Strong historical earthquakes (M > 7) and the presence of known seismic gaps imply a high level of seismic hazard. A synthesis of recent studies of active tectonics in the region is presented, including inland and underwater observations. The branching of the NAF is explained in terms of increasing influence of the extension. Historical information and instrumental seismicity are reinterpreted in order to have a critical appraisal of the existence of large seismic gaps in the central and eastern Marmara Sea. Focal mechanisms of strong earthquakes are used to obtain orientation and shape factor of the deviator of the stress tensor. The resulting tensor is in shear regime (sigma(2) vertical) but close to extension (R=0.93) with a, oriented N145 degrees 0. A microseismic experiment with 48 stations distributed around the Marmara Sea was carried out in October-December 1995. A total of 137 microearthquakes were located and 23 of those were selected to obtain focal mechanism solutions. The epicentral distribution indicates activity along the system of pull-apart basins north of the Marmara Sea. The segment between Marmara Sea and the Saros Bay, activated in 1912, and the Gulf of Izmit, site of the 1754 earthquake, are now silent. Seismic activity is very linear along the northern branch of the NAF, but it is more diffused on the Bursa and Iznik branches, southeast of the Marmara Sea. The stress tensor obtained from the focal mechanisms of the micro-earthquakes is compared to the one inverted from teleseismic data. The microseismic stress is compatible with a shear (intermediate) regime like the one obtained from strong earthquakes, though not as well constrained, one of the acceptable solutions having the same orientation but different shape (R=0.5). (C) 2000 Elsevier Science B.V. All rights reserved