94 research outputs found
Paraunitary oversampled filter bank design for channel coding
Oversampled filter banks (OSFBs) have been considered for channel coding, since their redundancy can be utilised to permit the detection and correction of channel errors. In this paper, we propose an OSFB-based channel coder for a correlated additive Gaussian noise channel, of which the noise covariance matrix is assumed to be known. Based on a suitable factorisation of this matrix, we develop a design for the decoder's synthesis filter bank in order to minimise the noise power in the decoded signal, subject to admitting perfect reconstruction through paraunitarity of the filter bank. We demonstrate that this approach can lead to a significant reduction of the noise interference by exploiting both the correlation of the channel and the redundancy of the filter banks. Simulation results providing some insight into these mechanisms are provided
Differential Regulatory Role of Pituitary Adenylate CyclaseâActivating Polypeptide in the Serum-Transfer Arthritis Model
OBJECTIVE:
Pituitary adenylate cyclase-activating polypeptide (PACAP) expressed in capsaicin-sensitive sensory neurons and immune cells has divergent functions in inflammatory and pain processes. This study was undertaken to investigate the involvement of PACAP in a mouse model of rheumatoid arthritis.
METHODS:
Arthritis was induced in PACAP(-/-) and wild-type (PACAP(+/+) ) mice by K/BxN serum transfer. General features of the disease were investigated by semiquantitative scoring, plethysmometry, and histopathologic analysis. Mechano- and thermonociceptive thresholds and motor functions were also evaluated. Metabolic activity was assessed by positron emission tomography. Bone morphology was measured by in vivo micro-computed tomography, myeloperoxidase activity and superoxide production by bioluminescence imaging with luminol and lucigenin, respectively, and vascular permeability by fluorescent indocyanine green dye study.
RESULTS:
PACAP(+/+) mice developed notable joint swelling, reduced grasping ability, and mechanical (but not thermal) hyperalgesia after K/BxN serum transfer. In PACAP(-/-) mice clinical scores and edema were significantly reduced, and mechanical hyperalgesia and motor impairment were absent, throughout the 2-week period of observation. Metabolic activity and superoxide production increased in the tibiotarsal joints of wild-type mice but were significantly lower in PACAP(-/-) animals. Myeloperoxidase activity in the ankle joints of PACAP(-/-) mice was significantly reduced in the early phase of arthritis, but increased in the late phase. Synovial hyperplasia was also significantly increased, and progressive bone spur formation was observed in PACAP-deficient mice only.
CONCLUSION:
In PACAP-deficient mice with serum-transfer arthritis, joint swelling, vascular leakage, hyperalgesia, and early inflammatory cell accumulation are reduced; in the later phase of the disease, immune cell function and bone neoformation are increased. Elucidation of the underlying pathways of PACAP activity may open promising new avenues for development of therapy in inflammatory arthritis.
© 2014 The Authors. Arthritis & Rheumatology is published by Wiley Periodicals, Inc. on behalf of the American College of Rheumatology
Frame Theory for Signal Processing in Psychoacoustics
This review chapter aims to strengthen the link between frame theory and
signal processing tasks in psychoacoustics. On the one side, the basic concepts
of frame theory are presented and some proofs are provided to explain those
concepts in some detail. The goal is to reveal to hearing scientists how this
mathematical theory could be relevant for their research. In particular, we
focus on frame theory in a filter bank approach, which is probably the most
relevant view-point for audio signal processing. On the other side, basic
psychoacoustic concepts are presented to stimulate mathematicians to apply
their knowledge in this field
Outdoor MIMO wireless channels: Models and performance prediction,â
Abstract-We present a new model for multiple-input multiple-output (MIMO) outdoor wireless fading channels which is more general and realistic than the usual i.i.d. model. The proposed model allows to investigate the behavior of channel capacity as a function of parameters such as the local scattering radius at the transmitter and the receiver, the distance between the transmit and receive arrays, and the antenna beamwidths and spacing. We show that capacity is driven by the spatial fading correlation and the condition number of the MIMO channel matrix through specific sets of propagation parameters. We use the new model to point out the existence of "pin-hole" channels which exhibit low fading correlation between antennas but still have poor rank properties and hence low capacity. We suggest guidelines for predicting high rank (and hence high capacity) in MIMO channels. We also show that even at long ranges high channel rank can easily be obtained under mild scattering conditions. Finally, we validate our results by simulations using ray tracing techniques
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