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14 research outputs found
Aurora kinase inhibitors: Progress towards the clinic
Author
A Kanda
AA Mortlock
+89Â more
AA Mortlock
AL Knowlton
B Lowenberg
B Zhao
C Ditchfield
C Soncini
CD Scharer
D Bebbington
D Fancelli
D Fancelli
Daniella Zheleva
DH Fu
DM Glover
DS Boss
EA Harrington
F Chan
F Girdler
F Girdler
G Gorgun
GC Fletcher
GM Cheetam
H Aliagas-Martin
H Goto
H Katayama
H Zhou
HL Chen
J Crawford
J Guo
J Infante
J McLaughlin
J Yang
JA Seamon
JD Oslob
JJ Tentler
JM Maris
JM Negri
JP Arbitrario
JP Jani
JR Bischoff
JR Diamond
K Anderson
KR Kelly
M Carmena
M Modugno
M Payton
M Tatsuka
MA Hardwicke
Madhu Kollareddy
Marian Hajduch
Martin Lepsik
MT Cancilla
N Portier
ND Adams
P Carpinelli
P Schoffski
Pathik Subhashchandra Brahmkshatriya
PD Andrews
Petr Dzubak
Q Liu
R Lin
R Paquette
R Sorrentino
R Tanaka
RB Cohen
RR Adams
RW Wilkinson
S Emanuel
S Hauf
S Howard
S Sen
S Tchatchou
S Wang
SL Warner
SL Warner
SM Len
T Marumoto
T Marumoto
T Shimomura
TE Rawson
W Reichardt
WF Zeng
WL Lano De
X Li
X Wang
X Yan
Y Ota
Y Tao
Y Tao
ZZ Lin
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
Full text link
Crossref
Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors
Author
Alam
Aliagas-Martin
+47Â more
Angell
Barr
Bennett
Bennett
Blease
Burns
Cao
Christopher
Claudia H. Ruiz
Derek R. Duckett
Gaillard
Graczyk
Gupta
Han
Hirosumi
Jiang
Kamenecka
Kamenecka
Kimberly
Kyriakis
Li Lin
LoGrasso
Marcel Koenig
Michael D. Cameron
Miyaura
Morrison
Pan
Parang
Paul
Pelaia
Phil LoGrasso
Resnick
Romain Noël
Ruckle
Shin
Stocks
Swahn
Swahn
Theodore M. Kamenecka
Weimin Chen
Weston
Wong
Xinyi Song
Youseung Shin
Yuan Yuan Ling
Yuanjun He
Zhang
Publication venue
'Elsevier BV'
Publication date
Field of study
No full text
Crossref
Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy
Author
A Gschwind
A Untergasser
+36Â more
AK Iyer
AL Hubbard
AS Nikonova
BR Paolella
C Cunningham
C Sawyers
D Nijhawan
DW Hein
DW Hein
E Lindhagen
EA Chiocca
F Innocenti
F Mertens
FL Muller
GR Abecasis
GV Kryukov
H Maiato
I Aliagas-Martin
I Niculescu-Duvaz
IA Kesisova
JP Basilion
KJ Martell
KJ Mavrakis
LR Howe
M Uhlen
MJ Ratain
N Issaeva
P Baranczewski
P Dey
S Boukouvala
S Kilpinen
S Sakaushi
SR Viswanathan
T O’Hare
WS El-Deiry
Y Liu
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Aurora Kinases as Druggable Targets in Pediatric Leukemia: Heterogeneity in Target Modulation Activities and Cytotoxicity by Diverse Novel Therapeutic Agents
Author
Aarthi Jayanthan
Aru Narendran
+61Â more
AS Moore
C Ditchfield
C Soncini
C-H Pui
C-H Pui
Claude Prigent
CS Nabzdyk
D Akahane
D Bhojwani
D Fancelli
EA Harrington
F Broekman
F Chan
F Locatelli
H Hochegger
H Katayama
I Aliagas-Martin
J Curry
J How
J Khan
J Yang
JA Seamon
JD Oslob
JJ Tentler
JP Arbitrario
JR Pollard
JR Sierra
K Yoshida
KR Kelly
KR Molhoek
M Carmena
M Kimura
M Li
M Steegmaier
M Tanudji
ME Tanenbaum
N Hégarat
N Keen
N Steeghs
O Gautschi
P Carpinelli
P Kaestner
P Meraldi
R Hrabakova
RK Tyler
S Emanuel
S Howard
S Lapenna
S Okabe
S Okabe
S Wang
SA Doggrell
SE Puumala
SMA Lens
T Ota
T Yamauchi
Tony H. Truong
W Lok
W Qi
Y Yakushijin
Yibing Ruan
Publication venue
'Public Library of Science (PLoS)'
Publication date
Field of study
No full text
Crossref
A MYC–aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer
Author
A Katsha
A Khwaja
+77Â more
A Klein
A Tannapfel
AD Tward
Anja Hohmeyer
Antti Poso
B Amati
C Welsch
CJ Sherr
CJ Sherr
CM Carlson
CM Schmidt
CM Shachaf
D Fancelli
D Huesken
Daniel Dauch
DF Calvisi
DJ Burgess
DL White
DW Felsher
DW Meek
EE Calle
G Falchook
Giacomo Cossa
H Beltran
H Braumüller
H Katayama
H Yuan
I Aliagas-Martin
J Bruix
J Liu
J Zuber
JD Watson
JE Delmore
Jean-Charles Nault
Jessica Zucman-Rossi
JM Mosquera
JP Vert
K Podsypanina
KL Chan
L Lu
L Soucek
L Zender
L Zender
Lars Zender
Lisa Hoenicke
LY Lu
M Brockmann
M Eilers
M Eilers
Martin Eilers
ME Diefenbacher
MT Kimura
N Meyer
Nisar P Malek
P Carpinelli
P White
PA Farazi
Przemyslaw Bozko
R Crane
R Lord
R Pérez Tamayo
R Rudalska
R Taub
Ramona Rudalska
Sandrine Imbeaud
Stefan Laufer
T Otto
T Wuestefeld
Tae-Won Kang
Tatu Pantsar
Tetyana Yevsa
Thomas Longerich
Torsten Wuestefeld
TW Kang
V Krizhanovsky
WC Gustafson
Y Ito
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
A Computational Model for Overcoming Drug Resistance Using Selective Dual-Inhibitors for Aurora Kinase A and Its T217D Variant
Author
Ali H. I.
Aliagas-Martin I.
+57Â more
Barakat K.
Barakat K.
Barakat K. H.
Bavetsias V.
Baxter C. A.
Constantinos Evangelinos
Davies D. L.
Dodson C. A.
Dolinsky T. J.
Dunbrack R. L.
Fancelli D.
Fenner A.
Friesen D. E.
Fu T.
Garcia A. E.
Goodsell D. S.
Grazioso G.
Greenman C.
He W.
Hess B.
Hornak V.
Howard S.
J. Torin Huzil
Jack Tuszynski
Jakalian A.
Jordheim L. P.
Kalé L.
Karaman M. W.
Khaled H. Barakat
Kirk E. Jordan
Kollareddy M.
Kollman P. A.
Kroemer R. T.
Kuhn B.
Leonis G.
Lin J. H.
Liu J.
Liu Q.
Michael Houghton
Morris G. M.
Morshed M. N.
Nowakowski J.
Pettersen E. F.
Sali A.
Sardon T.
Schoffski P.
Sen S.
Shao J.
Shi H.
Sloane D. A.
Tari L. W.
Totrov M.
Wishart D. S.
Wissing M. D.
Xie L.
Yang Y.
Zhao B.
Publication venue
'American Chemical Society (ACS)'
Publication date
Field of study
No full text
Crossref
Physicochemical and DMPK In Silico Models: Facilitating Their Use by Medicinal Chemists
Author
Bickerton G. R.
Cruciani G.
+49Â more
Cruciani G.
Daniel F. Ortwine
Desai P. V.
Faller B.
Forina M.
Gao H.
Ghose A. K.
Gleeson M. P.
Gleeson M. P.
Gleeson M. P.
Gleeson M. P.
Gupta R.
Hann M. M.
Heffron T. P.
Hewitt M.
Hill A. P.
Hopfinger A. J.
Ignacio Aliagas
Kozopas K. M.
Lee P. H.
Leeson P. D.
Leeson P. D.
Lipinski C. A.
Liu L.
Liu L.
Lobell M.
Martin Y. C.
Milletti F.
Muchmore S. W.
Nicola G.
Obrezanova O.
Patterson D. E.
Peng Z.
Plewczynski D.
Ritchie T. J.
Rush T. S.
Sastry G. M.
Scannell J. W.
Segall M.
Segall M. D.
Stewart K. D.
Sushko I.
Tarcsay A.
Thai K.-M.
Wager T. T.
Wager T. T.
Wenlock M. C.
Willett P.
Zientek M.
Publication venue
'American Chemical Society (ACS)'
Publication date
Field of study
No full text
Crossref
Stathmin and microtubules regulate mitotic entry in HeLa cells by controlling activation of both Aurora kinase A and Plk1
Author
Aliagas-Martin
Alli E
+70Â more
Alli E
Archambault V
Belletti B
Brattsand G
Carney BK
Carney BK
Cervigni RI
Chen Y
Dutertre
Efimov A
Eyers PA
Ezratty EJ
Fu S
Gadea BB
Gleixner KV
Grinshtein N
Grosstessner-Hain
Gundersen GG
Hoar K
Holmfeldt P
Johnsen JI
Jordan MA
Jordan MA
Jordan MA
Joukov V
Kang YH
Katayama H
Kesseler KJ
Kishi K
Koivusalo R
Kramer A
Larsson N
Lee KS
Leinung M
Lenart P
Lens SM
Liang XJ
Lindqvist A
Lowery DM
Lynne Cassimeris
Macurek L
McKenzie L
Michal AM
Mistry SJ
Mitra M
Molli PR
Ohashi S
Perry JA
Polager S
Reinhardt HC
Rieder CL
Rieder CL
Santamaria A
Sardon T
Scheffner M
Scutt PJ
Seki A
Song B
Soung NK
Stephen Doxsey
Toya M
Trunnell NB
Tsvetkov L
Van Horn RD
Victoria C. Silva
Wang R
Xu D
Yuan H
Zhang HZ
Zou J
Publication venue
'American Society for Cell Biology (ASCB)'
Publication date
Field of study
No full text
Crossref
Phthalazinone Pyrazole Enhances the Hepatic Functions of Human Embryonic Stem Cell-Derived Hepatocyte-Like Cells via Suppression of the Epithelial-Mesenchymal Transition
Author
A Treyer
AB D’Assoro
+55Â more
AK Reka
AM Wobus
AV Bakin
B Li
C Billottet
C Cicchini
Chang-Woo Song
D Chen
Dae-Sung Kim
DR Xu
F Garibaldi
H Katayama
Han-Jin Park
HJ Park
HM Kim
Hyemin Kim
I Aliagas-Martin
J Chen
J Corchero
J Yang
JC Davila
JE Lee
Ji-Woo Kim
JP Li
JP Li
JP Thiery
JP Thiery
K Anderson
M Baxter
ME Prime
MG Manfredi
MI Yovchev
MJ Zamek-Gliszczynski
N Kaplowitz
N Keen
O Goldman
P Godoy
P Samavarchi-Tehrani
RA Wilke
S Grotegut
S Hauf
S Kawashima
Seokjoo Yoon
SJ Grille
SS Choi
T Shimomura
U Cavallaro
V Sehdev
XB Wan
Y Kamiyama
Y Xi
YH Ding
Young-Jun Choi
Z Li
Z Lu
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Development of o
Author
Adams N. D.
Aliagas-Martin I.
+81Â more
Anandan S.-K.
Anastassiadis T.
Asteriti I. A.
Bardelle C.
Barlaam B.
Bearss D. J.
Beattie J. F.
Bebbington D.
Belanger D. B.
Berndt N.
Boss D. S.
Breault G. A.
Brunger A. T.
Cee V. J.
Chakravarty A.
Charter N. W.
Cheung C. H. A.
Cheung C. H. A.
Coumar M. S.
Dar A. A.
DeLano W. L.
Dodson C. A.
Emsley P.
Ernst Schonbrunn
Fancelli D.
Fancelli D.
Fancelli D.
Garuti L.
Girdler F.
Gizatullin F.
Gorgun G.
Green M. R.
Harrington E. A.
Harshani R. Lawrence
Harsukh Gevariya
Herr R. J.
Hua Yang
Jester B. W.
Jin Q. Cheng
Jin-Yi Zhu
Kabsch W.
Kang N. S.
Keen N.
Keen N.
Koresawa M.
Libertini S.
Lietha D.
Liu M.
Lok W.
Manfredi M. G.
Manfredi M. G.
Martin M. P.
Marumoto T.
Mathew P. Martin
Mercedes Rodriguez
Moriarty K. J.
Mortlock A. A.
Nicholas J. Lawrence
Ochi T.
Pearce L. R.
Perez Fidalgo J. A.
Pollard J. R.
Portella G.
Robert Kendig
Roberta Pireddu
Roy Elias
Saeki T.
Saïd M. Sebti
Sevil Ozcan
Shang X.
Shimomura T.
Sloane D. A.
Soncini C.
Tari L. W.
Tomita M.
Vader G.
Wilkinson R. W.
Yeung S.-C. J.
Yu T.
Yunting Luo
Zhang J.
Publication venue
'American Chemical Society (ACS)'
Publication date
Field of study
No full text
Crossref
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