47 research outputs found
Scale-free networks are not robust under neutral evolution
Recently it has been shown that a large variety of different networks have
power-law (scale-free) distributions of connectivities. We investigate the
robustness of such a distribution in discrete threshold networks under neutral
evolution. The guiding principle for this is robustness in the resulting
phenotype. The numerical results show that a power-law distribution is not
stable under such an evolution, and the network approaches a homogeneous form
where the overall distribution of connectivities is given by a Poisson
distribution.Comment: Submitted for publicatio
Quasiperiodic Envelope Solitons
We analyse nonlinear wave propagation and cascaded self-focusing due to
second-harmonic generation in Fibbonacci optical superlattices and introduce a
novel concept of nonlinear physics, the quasiperiodic soliton, which describes
spatially localized self-trapping of a quasiperiodic wave. We point out a link
between the quasiperiodic soliton and partially incoherent spatial solitary
waves recently generated experimentally.Comment: Submitted to PRL. 4 pages with 5 figure
Quasiperiodic Hubbard chains
Low energy properties of half-filled Fibonacci Hubbard models are studied by
weak coupling renormalization group and density matrix renormalization group
method. In the case of diagonal modulation, weak Coulomb repulsion is
irrelevant and the system behaves as a free Fibonacci chain, while for strong
Coulomb repulsion, the charge sector is a Mott insulator and the spin sector
behaves as a uniform Heisenberg antiferromagnetic chain. The off-diagonal
modulation always drives the charge sector to a Mott insulator and the spin
sector to a Fibonacci antiferromagnetic Heisenberg chain.Comment: 4 pages, 4 figures; Final version to appear in Phys. Rev. Let
Quantum Return Probability for Substitution Potentials
We propose an effective exponent ruling the algebraic decay of the average
quantum return probability for discrete Schrodinger operators. We compute it
for some non-periodic substitution potentials with different degrees of
randomness, and do not find a complete qualitative agreement with the spectral
type of the substitution sequences themselves, i.e., more random the sequence
smaller such exponent.Comment: Latex, 13 pages, 6 figures; to be published in Journal of Physics
Remarks on the Spectral Properties of Tight Binding and Kronig-Penney Models with Substitution Sequences
We comment on some recent investigations on the electronic properties of
models associated to the Thue-Morse chain and point out that their conclusions
are in contradiction with rigorously proven theorems and indicate some of the
sources of these misinterpretations. We briefly review and explain the current
status of mathematical results in this field and discuss some conjectures and
open problems.Comment: 15,CPT-94/P.3003,tex,
Transmission and Spectral Aspects of Tight Binding Hamiltonians for the Counting Quantum Turing Machine
It was recently shown that a generalization of quantum Turing machines
(QTMs), in which potentials are associated with elementary steps or transitions
of the computation, generates potential distributions along computation paths
of states in some basis B. The distributions are computable and are thus
periodic or have deterministic disorder. These generalized machines (GQTMs) can
be used to investigate the effect of potentials in causing reflections and
reducing the completion probability of computations. This work is extended here
by determination of the spectral and transmission properties of an example GQTM
which enumerates the integers as binary strings. A potential is associated with
just one type of step. For many computation paths the potential distributions
are initial segments of a quasiperiodic distribution that corresponds to a
substitution sequence. The energy band spectra and Landauer Resistance (LR) are
calculated for energies below the barrier height by use of transfer matrices.
The LR fluctuates rapidly with momentum with minima close to or at band-gap
edges. For several values of the parameters, there is good transmission over
some momentum regions.Comment: 22 pages Latex, 13 postscript figures, Submitted to Phys. Rev.
The nowcasting SAF products and services: recent improvements in the new SW packages PPS v2018 and GEO v2018 and future plans
Presentación realizada en la 3rd European Nowcasting Conference, celebrada en la sede central de AEMET en Madrid del 24 al 26 de abril de 2019
A Quantitative Study of the Mechanisms behind Thymic Atrophy in Gαi2-Deficient Mice during Colitis Development
Mice deficient for the G protein subunit Gαi2 spontaneously develop colitis, a chronic inflammatory disease associated with dysregulated T cell responses. We and others have previously demonstrated a thymic involution in these mice and an aberrant thymocyte dynamics. The Gαi2−/− mice have a dramatically reduced fraction of double positive thymocytes and an increased fraction of single positive (SP) thymocytes. In this study, we quantify a number of critical parameters in order to narrow down the underlying mechanisms that cause the dynamical changes of the thymocyte development in the Gαi2−/− mice. Our data suggest that the increased fraction of SP thymocytes results only from a decreased number of DP thymocytes, since the number of SP thymocytes in the Gαi2−/− mice is comparable to the control littermates. By measuring the frequency of T cell receptor excision circles (TRECs) in the thymocytes, we demonstrate that the number of cell divisions the Gαi2−/− SP thymocytes undergo is comparable to SP thymocytes from control littermates. In addition, our data show that the mature SP CD4+ and CD8+ thymocytes divide to the same extent before they egress from the thymus. By estimating the number of peripheral TREC+ T lymphocytes and their death rate, we could calculate the daily egression of thymocytes. Gαi2−/− mice with no/mild and moderate colitis were found to have a slower export rate in comparison to the control littermates. The quantitative measurements in this study suggest a number of dynamical changes in the thymocyte development during the progression of colitis
Effect of ochratoxin A on the intestinal mucosa and mucosa-associated lymphoid tissues in broiler chickens
The immunotoxic effect of ochratoxin A (OTA) on the intestinal mucosa-associated lymphoid tissue and its cytotoxic action on the intestinal epithelium were studied in broiler chickens experimentally treated with the toxin. From the 7th day of life, 80 male broiler chickens (Ross 308) were randomly divided into four groups of 20 birds each. The three experimental groups (E1-3) were treated with OTA for 28 days (E1: 50 μg/kg body weight [bw]/day; E2: 20 μg/kg bw/day; E3: 1 μg/kg bw/day) and the fourth group served as control. Histological examination of the intestinal mucosa and immunohistochemical staining for identification of CD4+, CD8+, TCR1 and TCR2 lymphocytes in the duodenum, jejunum and ileocaecal junction were performed, and CD4+/CD8+ and TCR1/TCR2 ratios were calculated. OTA toxicity resulted in decreased body weight gain, poorer feed conversion ratio, lower leukocyte and lymphocyte count, and altered intestinal mucosa architecture. After 14 days of exposure to OTA, immunohistochemistry showed a significant reduction of the lymphocyte population in the intestinal epithelium and the lamina propria. After 28 days of exposure, an increase in the CD4+ and CD8+ values in both the duodenum and jejunum of chickens in Groups E1 and E2 was observed, but the TCR1 and TCR2 lymphocyte counts showed a significant reduction. No significant changes were observed in Group E3. The results indicate that OTA induced a decrease in leukocyte and lymphocyte counts and was cytotoxic to the intestinal epithelium and the mucosa-associated lymphoid tissue, altering the intestinal barrier and increasing susceptibility to various associated diseases