Dispersion of responsive functional polymer colloids for advanced applications [Dispersions de colloïdes polymères fonctionnels, stimulables pour des applications avancées]

The synthesis and the use of dispersion of functional polymer colloids are currently the subject of an evergrowing interest in academic and industrial fields. This article emphasizes on richness and creativity of the polymerization in dispersed media to produce stimuli responsive (multi)functional particles with controlled architecture and chemical structure. Through some selected examples dealing with the fields of materials, health and optoelectronic, this review presents the progress in this field and some of the pending challenges

Polymerization of cellulose nanocrystals-based Pickering HIPE towards green porous materials

Porous materials were produced based on high internal phase emulsions (HIPE) formulation stabilized by modified cellulose nanocrystals (CNCs). CNCs were first modified with bromoisobutyryl bromide and used as Pickering emulsion stabilizers to formulate highly concentrated inverse emulsions. Solid foams with an open porosity were successively produced by free radical polymerization of styrene/divinylbenzene continuous phase. The final materials were characterized regarding their cell size distribution, porosity and mechanical properties and then compared with well-known styrene/DVB polyHIPE stabilized either with usual surfactants or solid particles

Tribological behavior of a polymer grafted on silanized silica probed with a nanotip

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Tribological behavior of a polymer grafted on silanized silica probed with a nanotip

no abstrac

Tribological behavior of a polymer grafted on silanized silica probed with a nanotip

International audienceno abstrac

Tribological behavior of a polymer grafted on silanized silica probed with a nanotip

no abstrac

Development of triazolyl-based pH responsive releasing systems

International audienc

Design of pH responsive clickable prodrugs applied to histone deacetylase inhibitors: A new strategy for anticancer therapy

The aim of this study was to develop clickable prodrugs bearing a tunable pH responsive linker designed for acidic pH-mediated release of histone deacetylase inhibitors. HDACi are an important class of molecules belonging to the epigenetic modulators used for innovative cancer strategies. The behavior of these prodrugs was determined by a bioluminescence resonance energy transfer assay in living tumor cells. This work demonstrated that this innovative type of clickable prodrugs entered cancer cells and showed restored anti proliferative properties attributed to the effective release of the HDAC inhibitors. A correlation between kinetic studies, dose responses, and biological activities was obtained, making such clickable prodrugs good candidates for new strategies in epigenetic-oriented anticancer therapie