6 research outputs found

    Exploring the causes of change in adolescent girls’ sexual behaviour in Begoro, Ghana

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    There is a changing trend in adolescent girls‘ sexual and reproductive behaviour in Ghana. However, contemporary perspectives on adolescent girls‘ sexual behaviours are largely missing hence this study. Thematic analysis of data collected through in-depth interviews with adolescent girls and community members as well as focus group discussions with adolescent boys identified several factors accounting for the changes in adolescent girls‘ sexual and reproductive behaviour. These factors include changes in girls‘ attitudes to traditional practices, diversity in the agents of socialization as well as the age at menarche. This has resulted in a clash of value system between girls‘ sexual behaviours and that of the elderly. Thus, the social context in which girls are experiencing sexual and reproductive life in Ghana is changing and this must be taken into consideration when designing any intervention to help adolescent girls become resilient in their sexual and reproductive lives.Keywords: adolescent girls, sexual behaviour, social change, Ghan

    Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

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    BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021.MethodsWe estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined.FindingsGlobally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer.InterpretationAs the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed

    Exploring the Causes of Change in Adolescent Girls’ Sexual Behaviour in Begoro, Ghana

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    There is a changing trend in adolescent girls‘ sexual and reproductive behaviour in Ghana. However, contemporary perspectives on adolescent girls‘ sexual behaviours are largely missing hence this study. Thematic analysis of data collected through in-depth interviews with adolescent girls and community members as well as focus group discussions with adolescent boys identified several factors accounting for the changes in adolescent girls‘ sexual and reproductive behaviour. These factors include changes in girls‘ attitudes to traditional practices, diversity in the agents of socialization as well as the age at menarche. This has resulted in a clash of value system between girls‘ sexual behaviours and that of the elderly. Thus, the social context in which girls are experiencing sexual and reproductive life in Ghana is changing and this must be taken into consideration when designing any intervention to help adolescent girls become resilient in their sexual and reproductive lives.Keywords: adolescent girls, sexual behaviour, social change, Ghana Il existe une tendance à l'évolution des comportements sexuels et de la reproduction chez les adolescentes au Ghana. Cependant, les perspectives contemporaines sur les comportements sexuels des adolescentes sont en grande partie manquantes, d'où cette étude. L'analyse thématique des données recueillies grâce à des entretiens approfondis avec des adolescentes et des membres de la communauté, ainsi que des discussions de groupes cibles avec des garçons adolescents ont identifié plusieurs facteurs qui expliquent les changements dans les comportements sexuels et de la reproduction chez les adolescentes. Ces facteurs incluaient des changements dans l'attitude des filles à l'égard des pratiques traditionnelles, la diversité chez les agents de la socialisation ainsi que l'âge de la ménarche. Cela a entraîné un choc de système de valeurs entre les comportements sexuels des filles et celui des personnes âgées. Ainsi, le contexte social dans lequel les filles connaissent une vie sexuelle et de la reproduction au Ghana évolue et cela doit être pris en compte lors de la conception d'une intervention pour aider les adolescentes à devenir résilientes dans leur vie sexuelle et de la reproduction.  Mots clés: adolescentes, comportement sexuel, changement social, Ghan

    Exploring the Causes of Change in Adolescent Girls’ Sexual Behaviour in Begoro, Ghana

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    31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

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