25 research outputs found
The global prevalence of IBS in adults remains elusive due to the heterogeneity of studies: a Rome Foundation working team literature review
Objectives The global prevalence of IBS is difficult to ascertain, particularly in light of the heterogeneity of published epidemiological studies. The aim was to conduct a literature review, by experts from around the world, of community-based studies on IBS prevalence. Design Searches were conducted using predetermined search terms and eligibility criteria, including papers in all languages. Pooled prevalence rates were calculated by combining separate population survey prevalence estimates to generate an overall combined meta-prevalence estimate. The heterogeneity of studies was assessed. Results 1451 papers were returned and 83, including 288 103 participants in 41 countries, met inclusion criteria. The mean prevalence among individual countries ranged from 1.1% in France and Iran to 35.5% in Mexico. There was significant variance in pooled regional prevalence rates ranging from 17.5% (95% CI 16.9% to 18.2%) in Latin America, 9.6% (9.5% to 9.8%) in Asia, 7.1% (8.0% to 8.3%) in North America/Europe/Australia/New Zealand, to 5.8% (5.6% to 6.0%) in the Middle East and Africa. There was a significant degree of heterogeneity with the percentage of residual variation due to heterogeneity at 99.9%. Conclusions The main finding is the extent of methodological variance in the studies reviewed and the degree of heterogeneity among them. Based on this, we concluded that publication of a single pooled global prevalence rate, which is easily calculated, would not be appropriate or contributory. Furthermore, we believe that future studies should focus on regional and cross-cultural differences that are more likely to shed light on pathophysiology
Bowel disturbances following acute gastroenteritis A psychobiophysiological model for the irritable bowel syndrome
SIGLEAvailable from British Library Document Supply Centre-DSC:DXN023567 / BLDSC - British Library Document Supply CentreGBUnited Kingdo
Surreptitious laxative abuse - An unusual cause of chronic diarrhoea
Singapore Medical Journal316596-598SIMJ
The prevalence of isolated unconjugated hyperbilirubinaemia (Gilbert's syndrome) in subjects attending a health screening programme in Singapore.
Singapore Medical Journal336588-58
The colonic air insufflation test indicates a colonic cause of abdominal pain: An aid in the management of irritable bowel syndrome
Journal of Clinical Gastroenterology18119-22JCGA
Melatonin improves bowel symptoms in female patients with irritable bowel syndrome: A double-blind placebo-controlled study
10.1111/j.1365-2036.2005.02673.xAlimentary Pharmacology and Therapeutics2210927-93
Validation of a graded response questionnaire for the diagnosis of gastroesophageal reflux disease in an asian primary care population
10.1097/MCG.0b013e3180653613Journal of Clinical Gastroenterology426680-68
Nonsteroidal anti-inflammatory drugs in chronic pain: Implications of new data for clinical practice
10.2147/JPR.S168188Journal of Pain Research111937-194