2,262 research outputs found

    ArchivesSpace Adventures: A Migration

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    On February 4, 2019, the University Archives and Southern Minnesota Historical Center at Minnesota State University, Mankato successfully launched a new archival tool for our patrons called ArchivesSpace. While this at first glance may not seem like a big deal, the journey that the archives undertook to transform this search tool from a set of static HTML pages (all 700+ of them) to an easy-to-use search engine contained danger around every corner. The team had to fend off lions, tigers, and bears and had to blaze a path through a thick forest of metadata and archival records. The journey traveled down a dark and scary path; the path less traveled. At the path’s end, the archives team used their superpowers and a little magic, and thus emerged triumphant with a bright and shiny new archival tool called ArchivesSpace. Okay, so maybe this is exaggerating a little bit. There were no lions, tigers or bears, no forests, no superpowers, no magic, but like any good story, this one has a great ending. A small archives unit from a mid-sized university archive used teamwork, investigative know-how, learned from others, and partnered with those, who had some serious technology skills, to transform all those webpages into a better search experience for the patrons. The journey that follows speaks of how in collaboration with the library systems team, archives staff successfully built a local ArchivesSpace instance

    ARCHON to ASpace: Adventures in Archives Migration

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    In August 2018, the University Archives and Southern Minnesota Historical Center at Minnesota State University, Mankato decided to migrate our finding aids and collection information from a hidden ARCHON database to a publicly available ArchivesSpace instance. This time sensitive decision was made with no budget available and in the midst of both a library system migration (Aleph to Alma/Primo) and an entire University website migration that affected us more than we initially thought. Three migrations is no big deal, right? This session will talk about our migration from design to implementation to “Oops! Where did that go?” We will share with you what worked and what didn’t in our path to creating a new searchable archives tool for our patrons

    Don\u27t Get Stranded...Join Us on Digital Preservation Island!

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    The weather started getting rough, the tiny ship was getting tossed. If not for the courage of the fearless crew, the digital objects would be lost. Loosely based on a popular TV show, this interactive presentation will provide a basic introduction to digital preservation terms, tools, edu-cational materials (including handouts), and digital preservation plans. The session will conclude with a group discussion and time to begin working on your own digital preservation plan worksheet

    Using LibApps to Manage the COVID-19 Community History Project

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    In this presentation, we will be providing an overview of our project; how we utilized LibApps; some project outcomes; and some final thoughts on using LibApps for this project

    TRX: A Formally Verified Parser Interpreter

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    Parsing is an important problem in computer science and yet surprisingly little attention has been devoted to its formal verification. In this paper, we present TRX: a parser interpreter formally developed in the proof assistant Coq, capable of producing formally correct parsers. We are using parsing expression grammars (PEGs), a formalism essentially representing recursive descent parsing, which we consider an attractive alternative to context-free grammars (CFGs). From this formalization we can extract a parser for an arbitrary PEG grammar with the warranty of total correctness, i.e., the resulting parser is terminating and correct with respect to its grammar and the semantics of PEGs; both properties formally proven in Coq.Comment: 26 pages, LMC

    The Bolocam Galactic Plane Survey IX: Data Release 2 and Outer Galaxy Extension

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    We present a re-reduction and expansion of the Bolocam Galactic Plane Survey, first presented by Aguirre et al. (2011) and Rosolowsky et al. (2010). The BGPS is a 1.1 mm survey of dust emission in the Northern galactic plane, covering longitudes -10 < \ell < 90 and latitudes |b| < 0.5 with a typical 1-\sigma RMS sensitivity of 30-100 mJy in a 33" beam. Version 2 of the survey includes an additional 20 square degrees of coverage in the 3rd and 4th quadrants and 2 square degrees in the 1st quadrant. The new data release has improved angular recovery, with complete recovery out to 80" and partial recovery to 300", and reduced negative bowls around bright sources resulting from the atmospheric subtraction process. We resolve the factor of 1.5 flux calibration offset between the v1.0 data release and other data sets and determine that there is no offset between v2.0 and other data sets. The v2.0 pointing accuracy is tested against other surveys and demonstrated to be accurate and an improvement over v1.0. We present simulations and tests of the pipeline and its properties, including measurements of the pipeline's angular transfer function. The Bolocat cataloging tool was used to extract a new catalog, which includes 8594 sources, with 591 in the expanded regions. We have demonstrated that the Bolocat 40" and 80" apertures are accurate even in the presence of strong extended background emission. The number of sources is lower than in v1.0, but the amount of flux and area included in identified sources is larger.Comment: 36 pages, 16 figures, accepted to ApJS. Data available from http://irsa.ipac.caltech.edu/data/BOLOCAM_GPS

    Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

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    SummaryParkinson's disease (PD), an adult neurodegenerative disorder, has been clinically linked to the lysosomal storage disorder Gaucher disease (GD), but the mechanistic connection is not known. Here, we show that functional loss of GD-linked glucocerebrosidase (GCase) in primary cultures or human iPS neurons compromises lysosomal protein degradation, causes accumulation of α-synuclein (α-syn), and results in neurotoxicity through aggregation-dependent mechanisms. Glucosylceramide (GlcCer), the GCase substrate, directly influenced amyloid formation of purified α-syn by stabilizing soluble oligomeric intermediates. We further demonstrate that α-syn inhibits the lysosomal activity of normal GCase in neurons and idiopathic PD brain, suggesting that GCase depletion contributes to the pathogenesis of sporadic synucleinopathies. These findings suggest that the bidirectional effect of α-syn and GCase forms a positive feedback loop that may lead to a self-propagating disease. Therefore, improved targeting of GCase to lysosomes may represent a specific therapeutic approach for PD and other synucleinopathies
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