Clinical performance of an alkasite-based bioactive restorative in class II cavities: a randomized clinical trial

Objective: This clinical study aimed to evaluate the clinical performance of an alkasite-based bioactive material by comparing it with a resin composite (RC) in the restoration of Class II cavities over a year. Methodology: A hundred Class II cavities were restored at 31 participants. Groups were as follows: Cention N (CN) (Ivoclar Vivadent, Schaan, Liechtenstein) and G-ænial Posterior (GP) (GC, Tokyo, Japan) in combination with G-Premio Bond (etch&rinse). Restorative systems were applied following manufacturers’ instructions. They were finished and polished immediately after placement and scored based on retention, marginal discoloration, marginal adaptation, sensitivity, surface texture, and color match using modified USPHS criteria after 1 week (baseline), 6 months, and 12 months. Statistical analyses were performed using chi-square, McNemar’s, and Kaplan Meier tests. Results: After 12 months, the recall rate was 87%. Survival rates of CN and GP restorations were 92.5% and 97.7%, respectively. Three CN and one GP restorations lost retention. Seven CN (17.9%) and five (11.6%) GP restorations were scored as bravo for marginal adaptation and no significant difference was seen between groups (p=0.363). One (2.7%) CN and two GP (4.7%) restorations were scored as bravo for marginal discoloration, but no significant difference was observed between groups(p=1.00). For surface texture, three (8.1%) CN and three (7%) GP restorations were scored as bravo (p=1.00). None of the restorations demonstrated post-operative sensitivity or secondary caries at any examinations. Conclusion: The tested restorative materials performed similar successful clinical performances after 12 months. ClinicalTrials.gov (NTC04825379)

One-year evaluation of a new restorative glass ionomer cement for the restoration of non-carious cervical lesions in patients with systemic diseases: a randomized, clinical trial

Objective: This randomized and clinical trial aimed to evaluate the performance of a new restorative Glass Ionomer Cement (GIC) for the restoration of non-carious cervical lesions (NCCLs) of patients with systemic diseases compared with a posterior resin composite after 12 months. Methodology: 134 restorations were placed at 30 patients presenting systemic diseases by a single clinician. NCCLs were allocated to two groups according to restorative system used: a conventional restorative GIC [Fuji Bulk (GC, Tokyo Japan) (FB)] and a posterior resin composite [G-ænial Posterior (GC, Tokyo Japan) (GP)] used with a universal adhesive using etch&rinse mode. All restorative procedures were conducted according to manufacturer’s instructions. Restorations were scored regarding retention, marginal discoloration, marginal adaptation, secondary caries, surface texture, and post-operative sensitivity using modified United States Public Health Service (USPHS) criteria after 1 week (baseline), 6, and 12 months. Descriptive statistics were performed using chi-square tests. Cochran Q and Mc Nemar’s tests were used to detect differences over time. Results: After 12 months, recall rate was 93% and the rates of cumulative retention failure for FB and GP were 4.9% and 1.6% respectively. Both groups presented similar alpha rates for marginal adaptation (FB 86.2%, GP 95.5%) and marginal discoloration (FB 93.8%, GP 97%) at 6-month recall, but FB restorations showed higher bravo scores than GP restorations for marginal adaptation and marginal discoloration after 12 months (p<0.05). Regarding surface texture, 2 FB restorations (3.1%) were scored as bravo after 6 months. All restorations were scored as alpha for secondary caries and postoperative sensitivity after 12 months. Conclusion: Although the posterior resin composite demonstrated clinically higher alpha scores than the conventional GIC for marginal adaptation and discoloration, both materials successfully restored NCCLs at patients with systematic disease after a year. Clinical relevance: Due to its acceptable clinical results, the tested conventional restorative GIC can be used for the restoration of NCCLs of patients with systemic diseases

Images of sexuality in the 16th century Ottoman society:

This thesis presents an alternative analysis of a 16th century work of erotic prose. Dâfi 'ii'I-gumûm ve Râfi 'ii 'I-humûm. It was penned by Mehmed Gazâlî, better known by his nickname Deli Birader. He was bom in 1466 in Bursa and died in 1534/1535 in Mecca. He was a scholar and a poet. He became courtier of Piyâle Bey, and then was admitted to the close circle of Prince Korkud in Manisa palace. He stayed there in a brief period before accession of Selim I to the throne in 1513. He dedicated Dâfi 'ii l-gumwn to Piyâle. After death of his benefactor Korkud, he worked in medreses in various Anatolian cities. He abandoned his career as a scholar soon, and settled in Be?sikta?s, Istanbul. The contemporary Ottoman biographers tell that because of the rumours concerning his involvement in "immoral affairs", and the execution of his patron İskender ?Celebi. Gazâlî needed to take resignation in Mecca for the rest of his life. The following study aims to (1) re-asses the current biographical information about Mehmed Gazali (2) re-instate the broader cultural context within which he produced his humour and (3) construe the representative-discursive world he built in his Dafi 'û 'l Gumûm. It proposes that the notion meclis and its various social-cultural associations provide a proper context to examine the convivial environment that inspires the literary imagery, and the human networks through which such a work is produced, transmitted and consumed. In the broadest sense of the term, there was, in early modern times, a widely practiced general "party" or "gathering" based on "witty conversation" (sohbel) as a core and containing many other elements including alcohol, food, music, dancers, plays and recitations. Such gatherings displayed an intersection of "patronage", "entertainment" and "literary- artistic production". They seem to be as important and popular among the court-dependent elites in Europe and Middle East as it was in the Ottoman Empire. The convivial mecalis corresponding to Brother Madcap's subsequent life stages (in Korkud's court, among his friends and with his elite patrons in Istanbul, and in Mecca) is taken as a particular historical case, In this respect, the thesis may facilitate a preliminary research agenda to study the network of social and historical relations that develop within the circle of the Ottoman cultural production. It is assumed that Dafi'ü'l Gumûm was constructed as a humour to enjoy primarily in the meclis context. Two basic questions are directed to the text: (1) How did Gazâlî create a humorous world? (2) Why could the reader find the text "funny"? The claim is that his thematic bag and literary strategies touch on and exploit certain tangible social dynamics and hierarchies (slavery, patronage, patriarchy, class differences e.g.). He avers human interactions that may prevail in real contexts (meclis, medrese, bathhouse etc.) and creates phobias and fears rooted in collective anxieties. To sum up, GazâIî's world of representations is not a discrete phenomenon detached from sociological reality, but if exaggerates that reality and makes a parody of it

Effects of in-office bleaching agent combined with different desensitizing agents on enamel

Objective: To analyze color change, microhardness and chemical composition of enamel bleached with in-office bleaching agent with different desensitizing application protocols. Materials and Methods: One hundred and seventeen polished anterior human enamel surfaces were obtained and randomly divided into nine groups (n=13). After recording initial color, microhardness and chemical composition, the bleaching treatments were performed as G1: Signal Professional White Now POWDER&LIQUID FAST 38% Hydrogen peroxide(S); G2: S+Flor Opal/0.5% fluoride ion(F); G3: S+GC Tooth Mousse/Casein Phosphopeptide-Amorphous Calcium Phosphate (CPPACP) paste(TM); G4: S+UltraEZ/3% potassium nitrate&0.11% fluoride(U); G5: S+Signal Professional SENSITIVE PHASE 1/30% Nano-Hydroxyapatite (n-HAP) suspension(SP); G6: S-F mixture; G7: S-TM mixture; G8: S-U mixture; G9: S-SP mixture. Color, microhardness and chemical composition measurements were repeated after 1 and 14 days. The percentage of microhardness loss (PML) was calculated 1 and 14 days after bleaching. Data were analyzed with ANOVA, Welch ANOVA, Tukey and Dunnett T3 tests (p<0.05). Results: Color change was observed in all groups. The highest ΔE was observed at G7 after 1 day, and ΔE at G8 was the highest after 14 days (p<0.05). A decrease in microhardness was observed in all groups except G6 and G7 after 1 day. The microhardness of all groups increased after 14 days in comparison with 1 day after bleaching (p>0.05). PML was observed in all groups except G6 and G7 after bleaching and none of the groups showed PML after 14 days. No significant changes were observed after bleaching at Ca and P levels and Ca/P ratios at 1 or 14 days after bleaching (p>0.05). F mass increased only in G2 and G6, 1 day after bleaching (p<0.05). Conclusions: The use of desensitizing agents containing fluoride, CPP-ACP, potassium nitrate or n-HAP after in-office bleaching or mixed in bleaching agent did not inhibit the bleaching effect. However, they all recovered microhardness of enamel 14 days after in-office bleaching

Fresh versus frozen-thawed blastocyst transfer in high responders

Objective: This study aimed to investigate and compare the pregnancy and live birth rates in IVF cycles of frozen-thawed embryo transfers and fresh embryo transfers in a group of women with a high risk of Ovarian hyperstimulation syndrome (OHSS). Material and methods: The study group consisted of 254 women with a high level of response to controlled ovarian hyperstimulation. The patients who received fresh cycle embryo transfers with calcium infusions are referred to as the Fresh Ca+ group, and those without the calcium therapy are called the Fresh Ca- group; and we used correspondingly similar terminology for the Frozen group. Results: We observed no statistically significant differences between the cycles of fresh and frozen-thawed embryo transfers in patients with a high risk of OHSS in terms of implantation, clinical pregnancy, and live birth rates. Furthermore, these implantation, clinical pregnancy and live birth rates were not different in the cycles with or without calcium treatment. There was no statistical difference in the OHSS rates between the fresh and frozen-thawed cycles; although, the OHSS rates were less in the two calcium infusion groups (Fresh Ca+ and Frozen-thawed Ca+) than in the without-calcium group. There was no OHSS development in the subjects of the Frozen-thawed Ca+ group. Conclusion: Our study results suggest that fresh and frozen-thawed embryo transfers have similar IVF results in patients with a high risk of OHSS. Calcium infusion is beneficial in preventing OHSS without altering pregnancy rates. Both IVF protocols with calcium infusion can safely be applied in high-responder patients without lowering success rates

Cadastral valuation as instrument for strategic planning

The article analyzes issues modern state improving of cadastral valuation methods. In this case, the role of the land and property complex in strategic and territorial planning is analyzed. The necessity of forecasting changes in the lands cadastral value for achieving strategic goals and the choice of town-planning solutions is shown

Разработка устройства детектирование движения и фильтрации изображения на ПЛИС

В процессе выполнения работы был проведён анализ методов фильтрации изображения, выделения границ и детектирования движения. Был разработана структурная схема системы фильтрации видео на ПЛИС и данная схема была реализована при помощи языка описания аппаратуры Verilog HDL для отладочной платы PYNQ-Z2. Было проведено сравнение производительности обработки видео фильтром Собеля на ПЛИС и на встроенном процессоре Cortex A-9. Разработка для ПЛИС велась в САПР Xilinx Vivado 2018.2 и ModelSim 10.3d.In the process of work analysis of image processing, edge and movement detection methods were carried out. Block diagram of FPGA video processing system was created and it was developed using Verilog HDL for PYNQ-Z2 development kit. Performance comparison of video processing using Sobel filter on FPGA and on Cortex A-9 processor was made. Xilinx Vivado 2018.2 CAD system and ModelSim 10.3d were used for FPGA development

Serum and follicular fluid concentration of stem cell factor in PCOS

Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in reproductive-aged women, which affects 5 to 20% of women in the reproductive age worldwide. This study aimed to compare the levels of SCF in serum and follicular fluid of PCOS patients with those of non-PCOS group and to investigate the relationship of SCF levels with ICSI success.Methods: This is an observational case control study that included the patients who underwent ICSI in the Infertility-IVF center at Ankara University Faculty of Medicine and in a private IVF center between March 2016 and February 2017. The study group consisted of 57 PCOS patients diagnosed according to the Rotterdam criteria and the control group consisted of 75 patients with normofollicular and regular menstrual cycles. Serum and follicular fluid samples were taken on day of oocyte retrieval. Serum and follicular fluid SCF levels were determined by ELISA using the SCF ELISA kit..Results: Serum and follicular fluid SCF levels in PCOS patients were found to be lower than in non-PCOS group. sSCF and ffSCF were statistically significantly higher who had clinical pregnancy than those who had no clinical pregnancy in the PCOS group.Conclusions: SCF levels are low in serum and follicular fluid in patients with PCOS and that the increase in SCF levels is associated with an increase in oocyte maturation and clinical pregnancy rates in PCOS.

Экономическая безопасность функционирования предприятия в условиях сетевой экономики

В наше время возникновение сетевых особенностей в экономике связывают с развитием информационных технологий, что приводит к эволюции современных экономических систем, развитию нерыночных механизмов регулирования и сетевых организационных структур. Другими словами, сетевые экономические отношения играют особую роль в процессе координации экономических взаимодействий. Данные изменения обостряют проблему экономической безопасности предприятия в условиях развития межорганизационных взаимодействий формального и неформального характера с позиции сетевой экономики