1 research outputs found
A Cascade Phosphinoylation/Cyclization/Desulfonylation Process for the Synthesis of 3‑Phosphinoylindoles
3-Phosphinoylindole
derivatives play important roles as pharmaceutical
drugs and ligands. A new method for the synthesis of 3-phosphinoylindole
derivatives has been achieved through silver-mediated cycloaddition
between N-Ts-2-alkynylaniline derivatives and H-phosphine oxides.
This transformation offers a straightforward route to the formation
of the C–P bond, indole ring, and desulfonylation in one step