(3S,12R,20S,24R)-20,24-Ep­oxy­dammarane-3,12,25-triol

In the title mol­ecule, C30H52O4, the three six-membered rings are in chair conformations, the cyclo­pentane ring is in an envelope form and the tetra­hydro­furan ring has a conformation inter­mediate between half-chair and sofa. In the crystal, mol­ecules are linked by inter­molecular O—H⋯O hydrogen bonds into helical chains along [100]. Two intra­molecular O—H⋯O hydrogen bonds are also present. One C atom of the tetrahydrofuran ring and its attached H atoms are equally disordered over two sets of sites

N′-(4-Fluoro­benzyl­idene)acetohydrazide

The title compound, C9H9FN2O, was prepared by the reaction of 4-fluoro­benzophenone and acethydrazide. In the mol­ecule, all non-H atoms are essentially coplanar [r.m.s. deviation = 0.065 (2) Å]. In the crystal, mol­ecules are linked into centrosymmetric dimers by pairs of inter­molecular N—H⋯O hydrogen bonds

N′-[1-(4-Chloro­phen­yl)ethyl­idene]acetohydrazide

In the title compound, C10H11ClN2O, the dihedral angle between the acetohydrazide group and the aromatic ring is 33.76 (9)°. In the crystal, inversion dimers linked by pairs of N—H⋯O hydrogen bonds generate R 2 2(8) loops

Measurement-device-independent QKD with Modified Coherent State

The measurement-device-independent quantum key distribution (MDI-QKD) protocol has been proposed for the purpose of removing the detector side channel attacks. Due to the multi-photon events of coherent states sources, real-life implementations of MDI-QKD protocol must employ decoy states to beat the photon-number-splitting attack. Decoy states for MDI-QKD based on the weak coherent states have been studied recently. In this paper, we propose to perform MDI-QKD protocol with modified coherent states (MCS) sources. We simulate the performance of MDI-QKD with the decoy states based on MCS sources. And our simulation indicates that both the secure-key rate and transmission distance can be improved evidently with MCS sources.The physics behind this improvement is that the probability of multi-photon events of the MCS is lower than that of weak coherent states while at the same time the probability of single-photon is higher

Expressions of Neuregulin 1β and ErbB4 in Prefrontal Cortex and Hippocampus of a Rat Schizophrenia Model Induced by Chronic MK-801 Administration

Recent human genetic studies and postmortem brain examinations of schizophrenia patients strongly indicate that dysregulation of NRG1 and ErbB4 may be important pathogenic factors of schizophrenia. However, this hypothesis has not been validated and fully investigated in animal models of schizophrenia. In this study we quantitatively examined NRG1 and ErbB4 protein expressions by immunohistochemistry and Western blot in the brain of a rat schizophrenia model induced by chronic administration of MK-801 (a noncompetitive NMDA receptor antagonist). Our data showed that NRG1β and ErbB4 expressions were significantly increased in the rat prefrontal cortex and hippocampus but in different subregions. These findings suggest that altered expressions of NRG1 and ErbB4 might be attributed to the schizophrenia. Further study in the role and mechanism of NRG1 and ErbB4 may lead to better understanding of the pathophysiology for this disorder

(6aS,11aR,11cS)-8-Sulfanylidene-2,3,5,6,6a,7,11,11a,11b,11c-decahydro-3a,7a-diaza-1H,4H-benzo[de]anthracen-3a-ium chloride hemihydrate

The title compound, C15H23N2S+·Cl−·0.5H2O, was prepared from (6aS,11aR,11cS)-2,3,5,6,6a,7,11,11a,11b,11c-deca­hydro-3a,7a-diaza-1H,4H-benzo[de]anthracene-8-one (sophocarpine) and Lawesson’s reagent. The thione-substituted ring is in an envelope conformation and the three other six-membered rings are in chair conformations. In the crystal, anions and cations are linked by N—H⋯Cl and weak C—H⋯Cl hydrogen bonds. One 0.5-occupancy solvent water mol­ecule lies on a twofold rotation axis and another 0.25-occupancy solvent water mol­ecule is in a general position. The H atoms of these water mol­ecules were not located or included in the refinement

Measurement-device-independent quantum key distribution with uncharacterized qubit sources

Measurement-device-independent quantum key distribution (MDIQKD) is proposed to be secure against any possible detection attacks. The security of the original proposal relies on the assumption that the legitimate users can fully characterize the encoding systems including sources. Here, we propose a MDIQKD protocol where we allow uncharacterized encoding systems as long as qubit sources are used. A security proof of the MDIQKD protocol is presented that does not need the knowledge of the encoding states. Simulation results show that the scheme is practical