The Directions of Creation of Unique Technologies in Medicine on the Basis of New Generation of Biocompatible Materials and Implants With Shape Memory

The article describes the main directions of creation of unique technologies in medicine on the basis of new generation of biocompatible materials and implants with shape memory effect (SME). Physical and biological fundamentals and principles of creating a new class of biocompatible superelastic TiNi-based materials were drafted. Manufacturing technique of TiNi-based materials with using the induction melting technique, self-extending high-temperature synthesis and powder metallurgy with a certain complex of properties for various fields of medicine have been developed

The Device for the Treatment of Diabetes with Use of Infrared Radiation and Porous TiNi Based Alloy

The research addresses the problem of design and development of a new needle-free method for diabetes treatment. New porous-permeable TiNi-based materials and new methods of IR-radiation effect on tissues of the body have been used in the research. The properties of porous alloys are similar to those of high-capacity materials that can hold a large volume of insulin solution in the porous structure of the material. With this, IR-radiation stimulates directed diffusion of insulin from the porous TiNi structure to the tissues of the body. This makes the basis for development of a needle-free device for diabetes treatment. The proposed technique does not cause skin irritation, and it is safe when used in practice. The efficiency of insulin delivery was evaluated in clinical studies. The results showed the potential of prolonged delivery for both insulin and other liquids

Biometrics of Jaw Models Analysis in Treating Tooth Position Anomalies with the Use of Orthodontic Shape Memory Apparatus

The paper presents the results of research in the field of orthodontic treatment of patients with the use of conventional bracket system methods as well as with the orthodontic thread and hollow tube made of superelastic nickelid titanium (TiNi) alloy, the method of measurement of plaster jaw models introduced by L. Persin. The study reveals the advantages of our newly developed apparatus for orthodontic tooth movement in the transverse and sagittal directions

Long-Term Results of Chest Wall Reconstruction After Tumor Resection Using TiNi Implants

The article's abstract is no available

Elimination of Mandibular Defects in Patients with Malignant Neoplasms Using the Poprus TiNi-alloys

The article presents the clinical observation of 16 patients with malignant neoplasms of the lower jaw. All the patients underwent resection of the mandible with the substitution for the flaws with endoprostheses of porous NiTi. In 10 cases a course of preoperative radiotherapy in a dose of 42-44 gr. was conducted. The results of surgical treatment showed high efficiency of the technology

The Technology of The Manufacturing Thin Wire of TiNi-based Alloys by Using Infrared Radiation

The paper describes the technology of manufacturing a thin nickel-titanium wire through direct exposure to infrared radiation (IR). The effect of IR on the change in the structure of a thin wire made from the TiNi-based alloy was studied during its manufacturing. A comparative analysis of the Ti, Ni and O concentration in the TiNi wire was carried out. The analysis was performed for both a thin wire exposed to infrared radiation and that not exposed to infrared radiation. The wire samples were studied using a scanning electron microscope with the energy dispersive analysis. The infrared radiation effect on the structure of the wire is shown after thermal treatment in the local area of the material

Surgery of False Joints of Long Tubular Bones in Children Using the Shape Memory Materials

The article presents the clinical observations of 15 patients aged from 10 months to 14 years with the false joints of long tubular bones of various etiology after their elimination by pathological tissues resection, placing the osteogenic tissue in the defect zone, the structures based on porous nickelid titanium saturated with poorly differentiated cellular elements of mesenchymal origin, fixation of fragments by brackets of nickelid titanium with shape memory. In all cases the obtained result was satisfactory and functional

A Study of the Pore Surface State of Porous TiNi-based Materials Obtained by SHS at Various Ignition Temperatures

Structural features of porous TiNi-based materials obtained by SHS at temperatures of synthesis beginning of400 Cand600 Chave been investigated. It is found that finely porous material with a porosity P=75 % was obtained at the temperature of400 C. A surface of pore walls contains a dendritic relief, oxycarbidenitride layer and a multitude of secondary phase particles. Phase and chemical composition of the material is non-uniform. SHS material obtained at the synthesis beginning temperature of600 °Cis characterized as a coarse-porosity one P=65 %. Nano- and micropores are practically absent. The oxycarbidenitride surface layer with a variable thickness is substantially free of secondary inclusions due to the more complete processes of alloy formation. This layer has an own substructure based on carbonitride and oxynitride layers

Evaluation of Porous TiNi-based Alloy as a Scaffold for Liver Tissue Engineering

Complex analysis of development of cells of liver – hepatocytes in the biocompatible scaffold, fabricated of porous-permeable TiNi-based alloy has been performed. Specific stages of development of cellular population in pores of scaffold are displayed in the present investigation. The stepwise characteristic of developing of hepatocytes in porous-permeable structure from TiNi-based alloy is demonstrated. Nanoporous surface of pores in incubator permit cells to be reliably fixed and produce growth to cellular colonies, and porous-permeable structure of scaffold allows penetrating to nutrients from environment during all time of investigation in vivo. Examination on CCl4-induced hepatitis has displayed effective antitoxic activity of population of hepatocytes in scaffold from TiNi-based alloy and their prolonged effect

Replacement of Temporomandibular Joint Head Using the Shape Memory Materials

In the article the clinical observations of 63 patients with destructive changes of the head of the mandible of various etiologies after its replacement by endoprosthesis based on the porous nickelid titanium were presented. In all cases the obtained result was satisfactory and functional