Effect of concentrated growth factors on frequency of alveolar Osteitis following partially-erupted mandibular third molar surgery: a randomized controlled clinical study

isik, gozde/0000-0001-9572-3049WOS: 000563499900001PubMed: 32807173Background the aim of this prospective study was to assess the effectiveness of concentrated growth factors (CGF) in preventing the development of alveolar osteitis (AO) after the extraction of partially-erupted mandibular third molars. Methods Seventy patients (26 men and 44 women) 18 years or older (mean age 25.86; range 18-35) underwent 140 third molar extractions. All the patients presented with bilateral, partially-erupted mandibular third molars and underwent surgical extractions. in each case, one socket received CGF and the other served as a control. the predictor variable was the CGF application and the sides were categorized as 'CGF' and 'non-CGF'. the outcome variable was the development of AO during the first postoperative week. Other study variables included age and gender. Data were analyzed using Cochran's Q test with the significance level set at aPvalue less than 0.05. Results the overall frequency of AO was 11.4% for the control group. the frequency of AO in the CGF group was significantly lower than in the non-CGF group (p < 0.001). Conclusions Based on the results of this study, application of CGF fibrin gel may decrease the risk of AO development after mandibular third molar surgery

Transpalatal Distraction Using Bone-Borne Distractor: Clinical Observations and Dental and Skeletal Changes

WOS: 000261351400014PubMed ID: 19022131Purpose: The aim of this clinical Study was to analyze the Outcome, complications, and long-term results of transpalatal distraction for the correction of maxillary transverse deficiency (MTD) and assess skeletal and dental changes in the sagittal, vertical, and transverse planes through cephalograms and dental casts. Patients and Methods: Ten adult patients with MTD were treated with a Transpalatal Distractor (Surgi-Tec, Bruges, Belgium). Lateral and posteroanterior cephalometric films and dental casts were taken before surgery and at the end of the consolidation period. The statistical analysis of cephalometric film and dental cast measurements was undertaken with paired t tests. Results: The intraoperative and postoperative problems encountered were damage to the central incisive teeth as a result of vertical osteotomy, Wound dehiscence after the latent period, pain during the distraction period, and loosening of the distractor and buccal displacement of the left alveolar segment during the consolidation period. Model analysis showed that the greatest amount of transverse increase was in the premolar region (7.07 film for first premolar and 7.10 mm for second premolar). Frontal cephalometric analysis indicated that transverse distances increased more at the alveolar level (7.75 mm) than in the maxillary base (5.25 mm) and nasal region (4.3 mm). The asymmetries between the left and right sides in both dental and skeletal expansions were statistically nonsignificant. The changes in the Sella-nasion-point A, Sella-nasion-point B, Sella-nasion and gonion-gnasion angles were statistically significant. Conclusions: According to the results Of this Study, transpalatal distraction was found to be a clinically effective technique for palatal expansion in adult patients with MTD. However, treatment planning and regular clinical follow-up visits are necessary for long-term clinical Success. (C) 2008 American Association of Oral and Maxillofacial SurgeonsDepartment of Scientific Research Projects, Ege University, TurkeyEge UniversityThis study was supported by the Department of Scientific Research Projects, Ege University, Turkey

Guided bone regeneration simultaneous with implant placement using bovine-derived xenograft with and without liquid platelet-rich fibrin: a randomized controlled clinical trial

Objective To assess augmentation success after guided bone regeneration (GBR) carried out simultaneously with implant placement using bovine-derived xenograft alone and in combination with liquid platelet-rich fibrin (liquid-PRF). Methods This randomized controlled clinical trial was conducted on patients with horizontal bone deficiency in the posterior regions of the mandible. After implant placement, GBR procedures were randomly performed using liquid-PRF-enriched bovine-derived xenograft (for the test group) and with bovine-derived xenograft alone (for the control group). To assess the change in augmentation thickness, the primary outcome of the study, cone beam computed tomography was carried out at the implant sites on completion and 6 months after surgery. The secondary outcomes were marginal bone level and implant survival rate at prosthetic delivery and at 6 months, 1 year, and 2 years follow-up after loading. The significance level was set at pResults Twenty patients with 50 implants were analyzed for the test group and 20 patients with 48 implants for the control group. At 6 months postoperatively, the mean values of augmentation thickness were 1.63 +/- 0.21 mm, 2.59 +/- 0.34 mm, and 3.11 +/- 0.36 mm for the test group and 1.34 +/- 0.14 mm, 2.49 +/- 0.24 mm, and 2.97 +/- 0.24 mm for the control group at 2 mm, 4 mm, and 6 mm below to the implant shoulder (p 0.001, p = 0.007, and p = 0.036, respectively). The mean marginal bone loss was found to be less than 1 mm for both study groups during the 2 years of follow-up after prosthetic loading. Implant survival rate was 100% for both study groups. Conclusion Bovine-derived xenograft alone and in combination with liquid-PRF are both successful in achieving bone augmentation around the implants and produce a small change in marginal bone level and a high implant survival rate after loading

Effects of Transmandibular Symphyseal Distraction on Teeth, Bone, and Temporomandibular Joint

WOS: 000270520900026PubMed ID: 19761921Purpose: The aim of this clinical study was to investigate the clinical effects and long-term results of the transmandibular symphyseal distraction technique for the correction of mandibular transverse deficiencies. This was achieved by assessing the dental, skeletal, and temporomandibular joint changes in the sagittal, vertical, and axial planes using cephalograms, dental casts, and computed tomography (CT). Patients and Methods: Seven patients with mandibular trans-verse deficiencies (3 females and 4 males), aged 14.3 to 22.5 years (mean 16.2), were treated with a bone-borne transmandibular distractor. Lateral and posteroanterior cephalometric films, CT scans of both temporomandibular joints, and dental casts were obtained preoperatively, at the end of the distraction period, and at the end of 3 years (clinical follow-up period). The clinical findings were assessed according to the morphologic and functional success criteria established by the Steering Group of European Collaboration on Cranial Facial Anomalies for patients with developmental dentofacial anomalies undergoing craniofacial distraction osteogenesis. The statistical analysis of cephalometric films and dental cast measurements was done using the paired t test. The mean postoperative examination period was 40 months (range 36 to 48). Results: The desired amount of distraction was achieved in all patients: (mean 6.48 nm). The intraoperative and postoperative complications encountered included damage to the central incisors during vertical osteotomy (I patient), wound dehiscence after a latent period (3 patients), mild temporomandibular joint pain during the distraction period (3 patients), and chronic gingivitis around the activation rods (7 patients). The success criteria for craniofacial distraction osteogenesis were fulfilled at the end of the 3-year follow-up period. Model analysis showed that the maximal amount of expansion was achieved at the premolar region (first premolar 5.79 mm, second premolar 5.07 mm). Frontal (posteroanterior) cephalograms taken at the end of the distraction period revealed significant increases in the bicondylar (0-35 mm), bigonion (3.43 mm), biantegonion (2.29 mm), and intermolar (4.0 mm) widths, and the ramal angle had decreased significantly (-1.64 degrees). The increase in the transverse measurements was greater at the dentoalveolar level than at the base of the mandible. Lateral cephalograms showed that transmandibular symphyseal distraction produced significant increases in the incisor mandibular plane angle (2.79 degrees) mid mandibular body length (1.72 mm). The effect of the procedure on the condyle was 2.5 degrees to 3 degrees of distolateral rotation as calculated using the CT scans. Dental crowding was resolved rapidly by the movement of the teeth into the distraction regenerate. Conclusions: The clinical and radiologic results of the present study have shown that a transmandibular distractor is a clinically effective bone-borne distractor for the correction of mandibular transverse deficiencies and anterior crowding. The follow-up cephalograms and CT scans showed the transverse skeletal stability of the distraction procedure and no permanent temporomandibular dysfunction. However, additional multicenter studies with more patients are necessary to precisely evaluate the long-term postdistraction changes on the skeleton, teeth, and temporomandibular joint. (C) 2009 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 67:2254-2265, 2009Department of Scientific Research Projects, Ege University, Bornova, TurkeyEge UniversityThis study was supported by the Department of Scientific Research Projects, Ege University, Bornova, Turkey

Physician compliance with American Heart Association guidelines for prevention of bacterial endocarditis in dental procedures

WOS: 000295498300013Aim: To evaluate physicians' compliance level with the American Heart Association (AHA) 2007 guidelines concerning the management of dental patients at risk for bacterial endocarditis. Materials and methods: This study included 103 patients with cardiac problems. The mean age was 41.02 +/- 15.22 years. According to consultations with physicians, the selection of the antibiotic, the timing, and the dosage were recorded on patients' forms prior to dental procedures by the researchers of the Department of Oral and Maxillofacial Surgery and Department of Oral Diagnosis and Radiology. Physicians' compliance level with the AHA 2007 recommendations was evaluated. Results: Antibiotic prophylaxis was prescribed for 75 (72.8%) of 103 patients with cardiac problems although it was not indicated. On the other hand, antibiotic prophylaxis was recommended with correct indication for 22 patients (21.3%). Two (9.1%) of these 22 patients were prescribed appropriate antibiotics, with correct dosage and timing by the physicians according to the AHA 2007 guidelines. Amoxicillin (20.0%) and combinations of the antibiotics (20.0%) were the first choices for prophylaxis. No antibiotic regimen was prescribed for 6 patients (5.9%), who did not require antibiotic prophylaxis according to the AHA 2007 guidelines. Conclusion: Clinicians are not always aware of the current clinical guidelines regarding antibiotic prophylaxis and must be aware of the contemporary guidelines and avoid prescribing excessive antibiotics to prevent emergence of resistant organisms

Multidisciplinary Approach to a Nonsyndromic Oligodontia Patient Using Advanced Surgical Techniques

WOS: 000292681900009PubMed ID: 21556386Treatment of a woman suffering from oligodontia and multiple diastemata with insufficient alveolar ridges in both the maxilla and mandible is described in this clinical report. The total number of missing teeth was 11 (excluding the wisdom teeth). The treatment strategy consisted of an interdisciplinary team approach of orthodontic, surgical, and prosthodontic phases. Sinus floor augmentation, alveolar ridge augmentation via vertical alveolar distraction, and lateral augmentation with ramus graft procedures were performed after fixed orthodontic treatment and prior to dental implant placement. Oral rehabilitation of the patient was completed with the placement of fixed prostheses in the maxillary and mandibular posterior edentulous areas. Early dental intervention improved the patient's appearance and minimized the onset of emotional and psychosocial problems. (Int J Periodontics Restorative Dent 2011;31:297-305.

Comparison of Autogenous Block Bone Graft and Screw Tent-Pole Techniques for Vertical Bone Augmentation in the Posterior Mandible: A Split-Mouth Randomized Controlled Study

uyanikgil, Yigit/0000-0002-4016-0522; KISAOGLU, Huseyin/0000-0002-3999-8846; isik, gozde/0000-0001-9572-3049; , meltem/0000-0002-7088-9701WOS:000623691700020Aim: To evaluate the effect on vertical bone augmentation of the screw tent-pole technique using particulate allograft in combination with injectable platelet-rich fibrin, and to compare this with autogenous block bone graft. Materials and Methods: This split-mouth randomized controlled study involved patients with bilateral partial edentulism and vertical bone loss in the posterior mandible. in each patient, the control side was treated with autogenous block bone graft harvested from the mandibular ramus and, on the test side, the screw tent-pole technique was employed, using particulate allograft in combination with injectable platelet-rich fibrin. All augmented sites were covered by leukocyte and platelet-rich fibrin membrane. The primary outcome variable of this study was the radiographic changes to bone height 6 months after augmentation. The secondary outcome variables were the percentage of newly formed bone and the implant survival rate. The data were analyzed with a significance level of alpha = 0.05. Results: of the 13 patients included, a total of 11 patients (7 females, 4 males; mean age 50.92) completed the study. The mean values of vertical bone gain were 1.72 0.78 mm for the test group and 2.83 +/- 0.89 mm for the control group, which constitutes a significant difference (P = .008). The percentage of newly formed bone was 18.08% +/- 2.17% for the test group and 14.26% +/- 1.76% for the control group. The difference between the groups was statistically significant (P < .001). The implant survival rates were 100% for both study groups. Conclusions: Based on the study results, screw tent-pole can be considered a feasible technique for bone augmentation. Further randomized studies will be necessary to fully evaluate vertical bone augmentation using the screw tent-pole technique, with different graft materials and with larger samples.Scientific Research Committee of the University [16-DIS-026]The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported by the Scientific Research Committee of the University (16-DIS-026)

THE EFFECTS OF MAXILLARY EXPANSION ON THE SOFT TISSUE FACIAL PROFILE

WOS: 000419184800001PubMed ID: 29114424Purpose: The aims of this retrospective study were to evaluate the possible changes in soft tissue facial profile induced by orthopedic rapid maxillary expansion (RME) and surgically assisted rapid maxillary expansion (SARME), and to correlate them with the underlying hard tissue alterations. Materials and Methods: 16 patients who received bone borne SARME and 25 patients who were subjected to RME using metal cast splint hyrax appliance were analyzed retrospectively. This research was conducted on lateral cephalometric radiographs taken on 2 occasions: before expansion (T1) and at the beginning of any further orthodontic treatment (T2). Investigated lateral cephalometric parameters consisted of Holdaway soft tissue measurements with some supplementary soft tissue, skeletal and dental assessments. Results: The acquisition of T2 cephalograms which conforms to the initiation of further orthodontic treatment corresponded to 83.25 +/- 3.51 days for SARME and 85.68 +/- 4.37 days for RME after the expansion was completed. The only significant change in soft tissue profile of the SARME group was a decrease in upper lip thickness (p<0.05), whereas in the RME group, decrease in soft tissue facial profile angle and increase in H angle were found to be statistically significant (p<0.05 for each). For the RME group, the changes in soft tissue facial profile angle and H angle correlated only with the changes in SNB angle (p<0.05). Conclusion: While bone-borne SARME did not seem to possess the potential to alter soft tissue profile, tooth-borne RME caused a more convex soft tissue profile related to a reduction in SNB