Impulsivity in bipolar disorder

WOS: 000270343400006Objective: Impulsivity as an important component in the initiation of behavior plays a central role in the pathogenesis of mood disorders, particularly bipolar disorder. The association between bipolar disorder and impulsivity has been clearly presented; however, there are still contradictory findings about the presence of impulsivity in bipolar patients during inter-episodic periods and whether it presents a risk factor for the development of multiple mood episodes (depressive, manic or mixed). The aim of this study was to assess the presence of impulsivity and the relationship with impulsivity-related characteristics in patients with bipolar disorder, Methods: The study was carried out in the Psychiatry Clinics of Cukurova University Faculty of Medicine and Erenkoy Training and Research Hospital for Psychiatric and Neurological Diseases. All consecutive patients gave written informed consent. The study group was composed of 60 consecutive bipolar disorder patients (29 female, 31 male) whereas the healthy control group consisted of 60 subjects (32 female, 28 male). The subjects were evaluated by using the Turkish version of the Barratt Impulsivity Scale-11 (BIS-11), Eysenck Personality Questionnaire Revised-Abbreviated Form (EPQR-A), Aggressions Questionnaire (AQ), Spielberger State-Trait Anger Expression Inventory (STAXI) and sociodemographic data form. Results: The two groups were similar to each other in means of gender ratio, age, marital and economical status except for education period. In the bipolar disorder group, the scores of impulsivity, aggression, dimensions of personality and anger were significantly higher than other groups. Correlations between scores of all scales were also significant. Conclusion: The present findings suggest that patients with bipolar disorder still present impulsive traits in interepisodic remission period. There were also significant correlations between impulsivity and other related-characteristics like aggression and anger. (Anatolian Journal of Psychiatry 2009; 10:198-203