172 research outputs found
Portraits of a Camoufleur
Portraits of a Camoufleur is a body of photographic work which features military veterans who have transitioned back and forth between the military and civilian world. The photographic sculptures serve as portraits created by stacking collected archive photographs together inside shadowbox frames. The photographs have also had camouflage patterns physically cut out of them which reveal more of the underlying images and experiences the veterans have provided. The work serves as a window into military experiences, attempting to close the gap that exists between military and civilian culture
Functional and Structural Changes Induced By cTNT-Related FHC Mutations in TNT1 Alter Actomyosin Binding Interactions
Cell cycle and lineage progression of neural progenitors in the ventricular-subventricular zones of adult mice
Proliferating neural stem cells and intermediate progenitors persist in the ventricular-subventricular zone (V-SVZ) of the adult mammalian brain. This extensive germinal layer in the walls of the lateral ventricles is the site of birth of different types of interneurons destined for the olfactory bulb. The cell cycle dynamics of stem cells (B1 cells), intermediate progenitors (C cells), and neuroblasts (A cells) in the V-SVZ and the number of times these cells divide remain unknown. Using whole mounts of the walls of the lateral ventricles of adult mice and three cell cycle analysis methods using thymidine analogs, we determined the proliferation dynamics of B1, C, and A cells in vivo. Achaete-scute complex homolog (Ascl)1(+) C cells were heterogeneous with a cell cycle length (T(C)) of 18–25 h and a long S phase length (T(S)) of 14–17 h. After C cells, Doublecortin(+) A cells were the second-most common dividing cell type in the V-SVZ and had a T(C) of 18 h and T(S) of 9 h. Human glial fibrillary acidic protein (hGFAP)::GFP(+) B1 cells had a surprisingly short Tc of 17–18 h and a T(S) of 4 h. Progenitor population analysis suggests that following the initial division of B1 cells, C cells divide three times and A cells once, possibly twice. These data provide essential information on the dynamics of adult progenitor cell proliferation in the V-SVZ and how large numbers of new neurons continue to be produced in the adult mammalian brain
The Journey of Drug Dependents towards Recovery
Drug addiction is a worldwide phenomenon which generates problems not only affecting families but the society as well. Addictive substances are rampant among our societies today and minors are easy victims. It is in this premise why the government provides rehabilitation and treatment to this at risk population. The researchers used qualitative case study method to get to know the experiences of the three participants in the rehabilitation agency, the DCTRCDD or Davao City Rehabilitation Center for Drug Dependents. The three participants were using prohibited drugs before admission to the center. The participants shared their journey towards recovery in the agency and because of this, they were able to conceptualize their vision in life and developed values for their welfare and development
Structural and Functional Characterization of Cardiac Troponin T Mutations in the TNT1 Domain That Cause Familial Hypertrophic Cardiomyopathy
Prevalence of periodontitis in patients with rheumatoid arthritis and systemic lupus erythematosus
Outcome measures of disease activity in inflammatory arthritis
The most common types of chronic inflammatory arthritis are rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. In order to assess the activity of these diseases and tailor therapy, several outcome measures have been developed. They include composite scores based on clinical findings, biochemical markers and patient questionnaires. This article discusses the most commonly used outcome measures and looks at their limitations in quantifying the complex clinical features of different types of inflammatory arthritis, focusing in particular on rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis
Outcome measures of disease activity for rare autoimmune rheumatic diseases
Systemic lupus erythematosus, scleroderma, myositis and Sjögren's syndrome are rare, complex, multi-systemic rheumatic diseases associated with significant morbidity and mortality. Thorough assessments of disease activity are required to guide clinical management and assess response to new therapies in clinical trials. This article reviews the commonly used outcome measures to assess this group of diseases and discusses the limitations of their use
Closed crack imaging using time reversal method based on fundamental and second harmonic scattering
A recent variant of time reversal imaging is employed for reconstructing images of a closed crack, based on both the fundamental and the second harmonic components of the longitudinal scattered field due to an incident longitudinal wave. The scattered field data are generated by a finite element model that includes unilateral contact with Coulomb friction between the crack faces to account for the Contact Acoustic Nonlinearity. The closure state of the crack is controlled by specifying a pre-stress between the crack faces. The knowledge of the scattered field at the fundamental (incident) frequency and the second harmonic frequency for multiple incident angles provides the required inputs for the imaging algorithm. It is shown that the image reconstructed from the fundamental harmonic closely matches the image that is obtained from scattering data in the absence of contact, although contact between the crack faces reduces the amplitude of the scattered field in the former case. The fundamental harmonic image is shown to provide very accurate estimates of crack length for low to moderate levels of pre-stress. The second harmonic image is also shown to provide acceptable estimates of crack length and the image is shown to correlate with the source location of second harmonic along the crack, which becomes increasingly localized near the crack tips for decreasing levels of pre-stress. The influence of the number of sensors on the image quality is also discussed in order to identify the minimum sensors number requirement. Finally, multiple frequency imaging is performed over a fixed bandwidth to assess the potential improvement of the imaging algorithm when considering broadband information
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