BioacPepFinder: Novel Bioinformatics Tool for the Discovery of Bioactive Peptides from Protein Digestion.

International audienc

BioacPepFinder: Discovery of bioactive peptides from protein digestion.

International audienc

BioacPepFinder: Discovery of bioactive peptides from protein digestion.

International audienc

BioacPepFinder: a pipeline for prediction of proteolysis-generated bioactive peptides usable for all protein sources.

International audienc

Nouveaux ingrédients et amélioration génétique : des solutions prometteuses pour améliorer les performances de croissance de la truite arc-en-ciel sur aliment végétal

Session : Génétique et SélectionNouveaux ingrédients et amélioration génétique : des solutions prometteuses pour améliorer les performances de croissance de la truite arc-en-ciel sur aliment végétal. 6. Journées de la Recherche Filière Piscicol

Integrative Metabolomics for Assessing the Effect of Insect (Hermetia illucens) Protein Extract on Rainbow Trout Metabolism

Nutrition of high trophic species in aquaculture is faced with the development of sustainable plant-based diets. Insects seem particularly promising for supplementing plant-based diets. However, the complex effect of whole insect meal on fish metabolism is not well understood, and even less is known about insect meal extracts. The purpose of this work was to decipher the metabolic utilization of a plant-based diet supplemented with the gradual addition of an insect protein extract (insect hydrolysate at 0%, 5%, 10% and 15%). 1H-NMR profiling was used to assess metabolites in experimental diets and in fish plasma, liver and muscle. A significant dose-dependent increase in growth and feed efficiency with increasing insect extract amounts was observed. The incremental incorporation of the insect extract in diet had a significant and progressive impact on the profile of dietary soluble compounds and trout metabolome. The metabolites modulated by dietary insect extracts in plasma and tissues were involved in protein and energy metabolism. This was associated with the efficient metabolic use of dietary free amino acids toward protein synthesis through the concomitant supply of balanced free amino acids and energy substrates in muscle. The findings provide new insights into how the dietary food metabolome affects fish metabolism