12,931 research outputs found

    Bounds on Z′Z^\prime from 3-3-1 model at the LHC energies

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    The Large Hadron Collider will restart with higher energy and luminosity in 2015. This achievement opens the possibility of discovering new phenomena hardly described by the Standard Model, that is based on two neutral gauge bosons: the photon and the ZZ. This perspective imposes a deep and systematic study of models that predicts the existence of new neutral gauge bosons. One of such models is based on the gauge group SU(3)C×SU(3)L×U(1)NSU(3)_C \times SU(3)_L \times U(1)_N called 3-3-1 model for short. In this paper we perform a study with Z′Z^\prime predicted in two versions of the 3-3-1 model and compare the signature of this resonance in each model version. By considering the present and future LHC energy regimes, we obtain some distributions and the total cross section for the process p+p⟶ℓ++ℓ−+Xp + p \longrightarrow \ell^{+} + \ell^{-} + X. Additionally, we derive lower bounds on Z′Z^\prime mass from the latest LHC results. Finally we analyze the LHC potential for discovering this neutral gauge boson at 14 TeV center-of-mass energy.Comment: 6 pages, 9 figures, 2 table

    Generalized q-deformed Correlation Functions as Spectral Functions of Hyperbolic Geometry

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    We analyse the role of vertex operator algebra and 2d amplitudes from the point of view of the representation theory of infinite dimensional Lie algebras, MacMahon and Ruelle functions. A p-dimensional MacMahon function is the generating function of p-dimensional partitions of integers. These functions can be represented as amplitudes of a two-dimensional c=1 CFT. In this paper we show that p-dimensional MacMahon functions can be rewritten in terms of Ruelle spectral functions, whose spectrum is encoded in the Patterson-Selberg function of three dimensional hyperbolic geometry.Comment: 12 pages, no figure

    The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models.

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    Toll-like receptors (TLRs) play an important role in the innate and adaptive immune responses to pathogens, and are the target of new vaccine adjuvants. TLR2 plays a role in parasite recognition and activation of immune responses during cutaneous leishmaniasis infection, suggesting that TLR2 could be targeted by adjuvants for use in Leishmania vaccines. We therefore explored using Pam2CSK4 (Pam2) and Pam3CSK4 (Pam3) lipopeptide adjuvants, which activate TLR2/6 and TLR2/1 heterodimers respectively, in vaccine models for parasitic infections.The use of lipopeptide adjuvants was explored using two vaccine models. For cutaneous leishmaniasis, the lipopeptide adjuvants Pam2 and Pam3 were compared to that of the Th1-driving double-stranded DNA TLR9 agonist CpG for their ability to improve the efficacy of the autoclaved Leishmania major (ALM) vaccine to protect against L. major infection. The ability of Pam2 to enhance the efficacy of a soluble Brugia malayi microfilariae extract (BmMfE) vaccine to protect against filarial infection was also assessed in a peritoneal infection model of B. malayi filariasis. Parasite antigen-specific cellular and humoral immune responses were assessed post-challenge.The use of lipopeptides in ALM-containing vaccines did not provide any protection upon infection with L. major, and Pam2 exacerbated the disease severity in vaccinated mice post-challenge. Pam2, and to a lesser extent Pam3, were able to elevate antigen-specific immune responses post-challenge in this model, but these responses displayed a skewed Th2 phenotype as characterised by elevated levels of IgG1. In the B. malayi vaccine model, the use of Pam2 as an adjuvant with BmMfE induced significant protective immunity to the same level as inclusion of an Alum adjuvant. Here, both Pam2 and Alum were found to enhance antigen-specific antibody production post-challenge, and Pam2 significantly elevated levels of antigen-specific IL-4, IL-5 and IL-13 produced by splenocytes.These data indicate that TLR2/6-targeting ligands could be considered as adjuvants for vaccines that require robust Th2 and/or antibody-dependent immunity

    Operator Product on Locally Symmetric Spaces of Rank One and the Multiplicative Anomaly

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    The global multiplicative properties of Laplace type operators acting on irreducible rank one symmetric spaces are considered. The explicit form of the multiplicative anomaly is derived and its corresponding value is calculated exactly, for important classes of locally symmetric spaces and different dimensions.Comment: Int. Journal of Modern Physics A, vol. 18 (2003), 2179-218
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