615 research outputs found

    Experimental assessment of four ultrasound scattering models for characterizing concentrated tissue-mimicking phantoms

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    International audienceTissue-mimicking phantoms with high scatterer concentrations were examined using quantitative ultrasound techniques based on four scattering models: the Gaussian Model (GM), the Faran Model (FM), the Structure Factor Model (SFM) and the Particle Model (PM). Experiments were conducted using 10- and 17.5-MHz focused transducers on tissue-mimicking phantoms with scatterer concentrations ranging from 1 to 25%. Theoretical BSCs were first compared with the experimentally measured BSCs in the forward problem framework. The measured BSC versus scatterer concentration relationship was predicted satisfactorily by the SFM and the PM. The FM and the PM overestimated the BSC magnitude at actual concentrations greater than 2.5% and 10%, respectively. The SFM was the model that better matched the BSC magnitude at all the scatterer concentrations tested. Secondly, the four scattering models were compared in the inverse problem framework to estimate the scatterer size and concentration from the experimentally measured BSCs. The FM did not predict the concentration accurately at actual concentrations greater than 12.5%. The SFM and PM need to be associated with another quantitative parameter to differentiate between low and high concentrations. In that case, the SFM predicted the concentration satisfactorily with relative errors below 38% at actual concentrations ranging from 10 to 25%

    Non-linear ultrasonic tomography of high-contrasted materials

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    International audienceThis study focuses on the ultrasonic characterization and imaging of elastic materials like cylinders or tubes. In this case, ultrasonic wave propagation is greatly perturbed by the difference in the acoustic impedance between the scatterer and the surrounding medium (soft tissues, water or coupling gel), which results in considerable parasite events such as the refraction, attenuation and scattering of the waves. The aim of this work is then to solve a non-linear inverse scattering problem. Analytical or algebraic approaches may be applied generally involving in a "classical" problem of minimization of the differences between modeling data and measurements. Several strategies can be used to model the forward problem and to solve the inverse problem simply, efficiently and accurately. The distorted diffraction tomography is an inversion iterative method and belongs to the class of algebraic reconstruction algorithms. This method was developed to increase the order of application of the Born approximation (in the case of weakly contrasted media) to higher orders. The iterations are performed numerically by solving the forward and inverse problems at every iteration after calculating an appropriate Green's function; the previous iteration serves in each case to define the surrounding medium with a variable background. This yields quantitative information about the scatterer, such as the speed of sound and the attenuation. Quantitative ultrasonic imaging techniques of this kind are of great potential value in fields such as medicine, underwater acoustics and non-destructive testing

    PCN87 The Cost Effectiveness of Cetuximab (Erbitux) in the Third Line Treatment of Metastatic Colorectal Cancer in the UK

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    Active control of scattered acoustic radiation: a real-time implementation for a three-dimensional object

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    International audienceThis paper presents an active noise control experiment designed to validate a real-time control strategy for reduction of the noise scattered from a three-dimensional body. The control algorithm relies on estimating the scattered noise by linear filtering of the total noise measured around the body; suitable filters are identified from off-line measurements. A modified Filtered-Error Least-Mean-Squares algorithm then leads to the adaptive filters which drive the secondary sources. The paper provides the numerical simulations using a Boundary Element Method which helped in designing a feasible experiment in an anechoic chamber with a limited number of control sources. Eventually a real-time pure-tone implementation with 14 ordinary loudspeakers and a large body is shown to yield on average a 10~dB reduction of the scattered noise at the error sensors, which is close to the optimum reduction predicted by the numerical simulations for the sensor arrangement

    Ultrasonic Computed Tomography

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    Ultrasonic Computed Tomography (UCT) is a full digital imaging technique, which consists in numerically solving the inverse scattering problem associated to the forward scattering problem describing the interaction of ultrasonic waves with inhomogeneous media. For weakly inhomogeneous media such as soft tissues, various approximations of the solution of the forward problem (straight ray approximation, Born approximation...), leading to easy-to-implement approximations of the inverse scattering problem (back-projection or back-propagation algorithms) can be used. In the case of highly heterogeneous media such as bone surrounded by soft tissues, such approximations are no more valid. We present here two non-linear inversion schemes based on high-order approximations. These methods are conceived like the prolongation of the methods implemented in the weakly inhomogeneous case for soft tissues. The results show the feasibility of this UCT approach to bones and its potential to perform measurements in vivo

    Distorted Born diffraction tomography: limits and applications to inverse the ultrasonic field scattered by an non-circular infinite elastic tube

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    International audienceThis study focuses on the application of ultrasonic diffraction tomography to noncircular 2D-cylindrical objects immersed in an infinite fluid. The distorted Born iterative method used to solve the inverse scattering problem be longs to the class of algebraic reconstruction algorithms. This method was developed to increase the order of application of the Born approximation (in the case of weakly-contrasted media) to higher orders. This yields quantitative in formation about the scatterer, such as the speed of sound and the attenuation. Quantitative ultrasonic imaging techniques of this kind are of great potential value in fields such as medicine, under water acoustics and non destructive testing

    A coprocessor for secure and high speed modular arithmetic

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    We present a coprocessor design for fast arithmetic over large numbers of cryptographic sizes. Our design provides a efficient way to prevent side channel analysis as well as fault analysis targeting modular arithmetic with large prime or composite numbers. These two countermeasure are then suitable both for Elliptic Curve Cryptography over prime fields or RSA using CRT or not. To do so, we use the residue number system (RNS) in an efficient manner to protect from leakage and fault, while keeping its ability to fast execute modular arithmetic with large numbers. We illustrate our countermeasure with a fully protected RSA-CRT implementation using our architecture, and show that it is possible to execute a secure 1024 bit RSA-CRT in less than 0:7 ms on a FPGA
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