429 research outputs found
Predictors of Mortality of Streptococcal Bacteremia and the Role of Infectious Diseases Consultation: A Retrospective Cohort Study.
Streptococcal bacteremia is associated with high mortality. Thia study aims to identify predictors of mortality among patients with streptococcal bacteremia.
This retrospective study was conducted at the Lausanne University Hospital, Switzerland, and included episodes of streptococcal bacteremia among adult patients from 2015 to 2023.
During the study period, 861 episodes of streptococcal bacteremia were included. The majority of episodes were categorized in the Mitis group (348 episodes; 40%), followed by the Pyogenic group (215; 25%). Endocarditis was the most common source of bacteremia (164; 19%). The overall 14-day mortality rate was 8% (65 episodes). The results from the Cox multivariable regression model showed that a Charlson comorbidity index >4 (P .001; hazard ratio [HR], 2.87; confidence interval [CI]: 1.58-5.22), Streptococcus pyogenes (P = .011; HR, 2.54;CI: 1.24-5.21), sepsis (P < .001; HR, 7.48; CI: 3.86-14.47), lower respiratory tract infection (P = .002; HR, 2.62; CI: 1.42-4.81), and absence of source control interventions within 48 hours despite being warranted (P = .002; HR, 2.62; CI: 1.43-4.80) were associated with 14-day mortality. Conversely, interventions performed within 48 hours of bacteremia onset, such as infectious diseases consultation (P < .001; HR, 0.29; CI: .17-.48) and appropriate antimicrobial treatment (P < .001; HR, .28; CI: .14-.57), were associated with improved outcome.
Our findings underscore the pivotal role of infectious diseases consultation in guiding antimicrobial treatment and recommending source control interventions for patients with streptococcal bacteremia
Lead in the marine environment: concentrations and effects on invertebrates
Lead (Pb) is a non-essential metal naturally present in the environment and often complexed with other elements (e.g., copper, selenium, zinc). This metal has been used since ancient Egypt and its extraction has grown in the last centuries. It has been used until recently as a fuel additive and is currently used in the production of vehicle batteries, paint, and plumbing. Marine ecosystems are sinks of terrestrial contaminations; consequently, lead is detected in oceans and seas. Furthermore, lead is not biodegradable. It remains in soil, atmosphere, and water inducing multiple negative impacts on marine invertebrates (key species in trophic chain) disturbing ecological ecosystems. This review established our knowledge on lead accumulation and its effects on marine invertebrates (Annelida, Cnidaria, Crustacea, Echinodermata, and Mollusca). Lead may affect different stages of development from fertilization to larval development and can also lead to disturbance in reproduction and mortality. Furthermore, we discussed changes in the seawater chemistry due to Ocean Acidification, which can affect the solubility, speciation, and distribution of the lead, increasing potentially its toxicity to marine invertebrates
Frequencies and Damping rates of a 2D Deformed Trapped Bose gas above the Critical Temperature
We derive the equation of motion for the velocity fluctuations of a 2D
deformed trapped Bose gas above the critical temperature in the hydrodynamical
regime. From this equation, we calculate the eigenfrequencies for a few
low-lying excitation modes. Using the method of averages, we derive a
dispersion relation in a deformed trap that interpolates between the
collisionless and hydrodynamic regimes. We make use of this dispersion relation
to calculate the frequencies and the damping rates for monopole and quadrupole
mode in both the regimes. We also discuss the time evolution of the wave packet
width of a Bose gas in a time dependent as well as time independent trap.Comment: 13 pages, latex fil
Evaluation of the Clinical Rule for Endocarditis in the Emergency Department Among Patients With Suspected Infective Endocarditis.
Dissipative dynamics of vortex arrays in trapped Bose-condensed gases: neutron stars physics on K scale
We develop a theory of dissipative dynamics of large vortex arrays in trapped
Bose-condensed gases. We show that in a static trap the interaction of the
vortex array with thermal excitations leads to a non-exponential decay of the
vortex structure, and the characteristic lifetime depends on the initial
density of vortices. Drawing an analogy with physics of pulsar glitches, we
propose an experiment which employs the heating of the thermal cloud in the
course of the decay of the vortex array as a tool for a non-destructive study
of the vortex dynamics.Comment: 4 pages, revtex; revised versio
Enhancement of the scissors mode of an expanding Bose-Einstein condensate
We study the time-evolution of the scissors mode of a Bose-Einstein
condensate during the ballistic expansion after release from the magnetic trap.
We show that despite the nontrivial character of the superfluid expansion, the
sinusoidal behavior of the scissor oscillations is recovered after an
asymptotic expansion, with an enhancement of the final amplitude. We
investigate this phenomenon with a condensate held in an elongated
magnetostatic potential, whose particular shape allows for the excitation of
the scissors mode.Comment: RevTeX, 5 figure
Finite-temperature simulations of the scissors mode in Bose-Einstein condensed gases
The dynamics of a trapped Bose-condensed gas at finite temperatures is
described by a generalized Gross-Pitaevskii equation for the condensate order
parameter and a semi-classical kinetic equation for the thermal cloud, solved
using -body simulations. The two components are coupled by mean fields as
well as collisional processes that transfer atoms between the two. We use this
scheme to investigate scissors modes in anisotropic traps as a function of
temperature. Frequency shifts and damping rates of the condensate mode are
extracted, and are found to be in good agreement with recent experiments.Comment: 4 pages, 3 figure
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