Temporal variations in mortality from the main causes of death in 2014-2018 in Khanty-Mansiysk Autonomous District-Ugra (Western Siberia)

The aim of this work is to analyze the temporal variations in mortality from the main groups of diseases and external causes in the period 2014-2018 in Khanty-Mansiysk Autonomous Okrug-Ugra (Western Siberia). Methods. Data on mortality wereobtained from the Medical Information and Analytical Center in Khanty-Mansiysk. To test the hypothesis about cyclic variations in mortality, wavelet analysis was applied. Results. Fluctuations in death rates from infectious diseases, neoplasms, mental disorders, diseases of the nervous system and circulatory system, pathology of the digestive system appeared to have a significant circannual rhythm. For diseases of the endocrine system, respiratory system, musculoskeletal and genitourinary system, circannualpattern of mortality was not observed. Mortality from socially significant diseases demonstrate two-year, annual and intra-annual rhythms. Significant rhythms of mortality from injuries with a six-month (p = 0.012) and near-annual (p = 0.045) periods may have an exogenous nature, while circaseptan activity (p = 0.055) seems to have a social genesis. Fluctuations in mortality from suicide occur in near-annual (p = 0.002) and semi-annual (p = 0.068) rhythms. Temporal variations of road traffic accidents are characterized by insignificant six-month and two-week rhythms. Conclusions. Our findings suggest that mortality in the study areahas various duration and number of periods of rhythms, low-energy rhythmic activity with pronounced inter-seasonal and day-to-day fluctuations in weather factors, a changed photoperiodic regime, and seasonal exacerbations of endemic zoonoses against the background of constant exposure to unmodified risk factors for the development of diseases presented in this paper. © 2020, Northern State Medical University. All rights reserved