17 research outputs found

    Some aspects of standardization of the stomatological gel «Sonident»

    Get PDF
    Introduction: The high prevalence of pathological inflammatory diseases of the parodontium talks about the necessity of realizing mass prophylactic and therapeutic measures. Medicinal facilities of a prolonged action are therefore perspective, creating a high therapeutic concentration of operating substance in the areas of the use without the considerable increase of medicinal substance level in system circulation. These requirements conform to medicinal tapes and gels, prolonging action of what has been achieved by immobilization of operating substances on various polymeric carriers. As a result of undertaken preliminary studies we worked out the composition and offered the technology of preparing the dental gel «Sonident», that has as operating substances a tincture of scholar-tree and nimesulid. The pharmacological study of the gel has shown antimicrobial, reparative, antiinflammatory, angyoprotectory activity and is recommended for the treatment and prevention of stomatological diseases. Purpose: Choice of methods authentication and quantitative determination of active substances in the experimental models of gel “Sonident” and studies of their physical-chemical properties for development of project AND on preparation. Materials and methods: Researches were conducted according to the generally-accepted pharmacopoeia methods of determining the original appearance of gel: its color, smell, homogeneity, pH level, microbiological cleanliness, quality reactions and quantitative determination. Results: The conducted research devised the methods of authentication of the operating substances. For the tincture of scholar-tree reactions we suggested the solution of chloride oxydic iron (on phenol compounds), with hydrochloric acid and zinc (on flavonoids), TLC (on rutin). For nimesulid reactions we propose the authentication method of UV-spectroscopy and TLC. Methods: the quantitative analysis is worked out on the content of nimesulid and sums of flavonoids in preparation. Determination was conducted on the spectrophotometer Specord 200. Adsorption spectrums took off in a cuvette with the thickness of layer a 10 mm at the wave-length of 299 nm (for nimesulid) and 467 nm (for the sum of flavonoids). The painted complexes of gel solution with a chlorous aluminium have maximums of absorption in the intervals of 385-460 nm (rutin) and 296 nm (nimesulid). Conclusions: Methods of authentication are devised and physical-chemical descriptions of stomatological gel “Sonident” are studied with the use of instrumental methods of analysis. For quantitative determination a spectrophotometry method is offered and it is first well-proven, that basis and tincture of scholar-tree do not influence the spectrum of absorption substance nimesulid and does not interfere with application of spectrophotometry for realization of quantitative analysis nimesulid in preparation

    On Kinetic Approach to Modeling of Sources of Electromagnetic Radiation Located in Planet/Stellar Electroctromagnetic Structures (abstract). Planetary Radio Emissions| PLANETARY RADIO EMISSIONS VII 7|

    No full text
    Electromagnetic radiation from stars and planets appeared at the different wavebands. Radiation is provided by accelerated particles originated from plasma electromagnetic structures which are named the particle sources. Structures are selfconsistent with inductive e.m. fields and collisionless hot plasma electrodynamics including plasma part formed by accelerated particles. Here quasifree acceleration by inductive eddy e.m. field takes place. The sources are related with the diffusion regions (DR) of plasma where we get weak particle magnetization and where plasma kinetic process of magnetic reconnection takes place. In the DR electric current can be parted on the diamagnetic and on the resistive components. Current components in DR source are in ratio G and the components are related with non accelerated (diamagnetic) particles and accelerated (resistive) particles. Parameter G is calculated via momentum and energy anisotropy parameters depending on shape of the particle velocity distribution function (VDF). Parameter G can be positive and negative; G defines resistive, diamagnetic and quasi-current free dynamics of the DR as a source of accelerated particles. The G is the e.m. analog of the acoustic Mach number M. Plasma DR structures are described by anomalous skin-scale and diamagnetic skin scale. We introduced criteria on value of plasma beta and on value of anisotropy parameters to get the DR plasma structures realization

    Examination of electromagnetic and magnetohydrodynamic processes in the induction furnace with a sectional mould

    No full text
    14.00; Translated from Russian (Probl. Spets. Elektrometall. 1987 v. 3(1) p. 60-66)SIGLEAvailable from British Library Document Supply Centre- DSC:9023.19(VR--3859)T / BLDSC - British Library Document Supply CentreGBUnited Kingdo
    corecore