Stigmatising and Racialising COVID-19: Asian People’s Experience in New Zealand

The Asian community — the second largest non-European ethnic community in New Zealand — plays an important role in combatting the COVID-19 pandemic, evidenced by their active advocation for border control and mass masking. Despite the long history of racial discrimination against the Asian population, the Asian community has experienced certain degrees of racial discrimination associated with the stigmatisation as the cause of the COVID-19 outbreak in New Zealand. Based on data from a quantitative online survey with 402 valid responses within the Asian communities across New Zealand and the in-depth interviews with 19 Asian people in Auckland, New Zealand, this paper will illustrate Asian people’s experience of racial discrimination and stigmatisation during the pandemic in the country. The survey shows that since the outbreak of COVID-19, under a quarter of the participants reported experiencing discrimination, and a third reported knowing an immediate contact who had experienced discrimination. However, when looking beyond their immediate social circle, an even higher proportion reported noticing racism and stigmatisation through the traditional or social media due to COVID-19. Major variations of the degree of racial discrimination experienced are determined by three demographic variables: ethnicity, age, and region. The in-depth interviews largely echoed the survey findings and highlighted a strong correlation between the perceived racial discrimination among the local Asian community and the stigmatisation associated with COVID-19. These findings are important for improving the way we manage future pandemics and other disasters within the context of the UN Sendai Framework for Disaster Risk Reduction

Impact and potential value of immunosenescence on solid gastrointestinal tumors

Solid gastrointestinal tumors often respond poorly to immunotherapy for the complex tumor microenvironment (TME), which is exacerbated by immune system alterations. Immunosenescence is the process of increased diversification of immune genes due to aging and other factors, leading to a decrease in the recognition function of the immune system. This process involves immune organs, immune cells, and the senescence-associated secretory phenotype (SASP). The most fundamental change is DNA damage, resulting in TME remodeling. The main manifestations are worsening inflammation, increased immunosuppressive SASP production, decreased immune cell antitumor activity, and the accumulation of tumor-associated fibroblasts and myeloid-derived suppressor cells, making antitumor therapy less effective. Senotherapy strategies to remove senescent cells and block key senescence processes can have synergistic effects with other treatments. This review focuses on immunoenescence and its impact on the solid TME. We characterize the immunosenescent TME and discuss future directions for antitumor therapies targeting senescence

A cross-sectional online survey of depression symptoms among New Zealand’s Asian community in the first 10 months of the COVID-19 pandemic

The COVID-19 pandemic has elevated levels of distress and resulted in anti-Asian discrimination in many countries. We aimed to determine the 10-month prevalence of depression symptoms in Asian adults in New Zealand during the pandemic and to see if this was related to experience of racism. An online survey was conducted and a stratified sample of 402 respondents completed the brief Centre for Epidemiological Studies-Depression (CES-D) scale. Analyses included: descriptive statistics, depression scores by age/gender, factor analysis of the 10 item CES-D and partial correlation network analysis of CES-D items together with questions about experience of racism. Results show that half of the sample reported clinically significant symptoms of depression. Depression was higher among younger participants but there was no gender difference. Internal consistency was high (α = 0.85) for the CES-D which revealed a clear two-factor structure. Network analysis suggested that sleeping problems might be the bridge between experiences of racism and depression. The prevalence of low mood was high with clinically significant levels of depressive symptoms. Depression was higher in younger people and had a modest positive correlation with personal experience of racism

Measuring the missing: Knowledge, risk perceptions and self-protection practices of COVID-19 among the Asian population in New Zealand: An online survey

AimAsians are the second largest and fastest growing non-European population in New Zealand but are under-researched in terms of their COVID-19 pandemic response. The paper aims to illustrates Asians’ risk perceptions and knowledge of COVID-19, and self-protection practices to avoid infection and prevent community transmission.Subject and methodsAn online survey was used to collect data and received 402 valid responses. Data analyses included: 1) a descriptive analysis by using Chi-square tests and a Kruskal-Wallis rank sum tests to explore associations between responses and the four demographic variables (i.e. age, gender, country of origin/ethnicity, and region); and 2) a correlation analysis between different survey objectives.ResultsThe descriptive analysis of the survey found that while ethnicity (within the Asian category) was the most influential variable that resulted in varying responses to many questions, gender and age were other two important variables in influencing the answering patterns. The correlation analysis found a positive correlation between the perceived ‘dangerousness’ of COVID-19 and respondents’ overall compliance behaviour to New Zealand authorities’ recommendations to prevent spread of COVID-19.ConclusionThe majority of the respondents provided correct answers to the questions about the vulnerable populations, symptoms, asymptomatic transmission and potential sequelae of COVID-19; however, their understanding of the availability of a cure for, and the incubation period of COVID-19 was not consistent with the official information. The research also found that the higher perceived dangerousness of COVID-19, the better compliance to self-protection practices among the surveyed population

Implantable and Biodegradable Macroporous Iron Oxide Frameworks for Efficient Regeneration and Repair of Infracted Heart

The construction, characterization and surgical application of a multilayered iron oxide-based macroporous composite framework were reported in this study. The framework consisted of a highly porous iron oxide core, a gelatin-based hydrogel intermediary layer and a matrigel outer cover, which conferred a multitude of desirable properties including excellent biocompatibility, improved mechanical strength and controlled biodegradability. The large pore sizes and high extent of pore interconnectivity of the framework stimulated robust neovascularization and resulted in substantially better cell viability and proliferation as a result of improved transport efficiency for oxygen and nutrients. In addition, rat models with myocardial infraction showed sustained heart tissue regeneration over the infract region and significant improvement of cardiac functions following the surgical implantation of the framework. These results demonstrated that the current framework might hold great potential for cardiac repair in patients with myocardial infraction

Optimum Size of Coal Pillar Dimensions Serving Mechanised Caving Longwall Face in a Thick Seam

Abstract：Chain Pillars serving longwall face is an important factor influencing the stability of the roadway surrounding rock in the fully mechanised caving longwall face. The reasonable width of the section coal pillar is proposed, combined with the theoretical analysis, numerical simulation and field measurement for the fully mechanised caving longwall face in thick seam in Jinzhuang coal mine. Results of the numerical simulation show that when the width of the section pillar increases to 24 m, there is an 8 m wide elastic zone in the coal pillar and a saddle-shaped vertical stress distribution, which shows that the coal pillar can maintain its stability. So the reasonable width of the coal pillar is 24 m, which is close to the result of theoretical calculation (23 m). The field observations also illustrate that the 30 m wide coal pillars in the first mining face is too large resulting in a waste of resources

New Zealand border restrictions amidst COVID-19 and their impacts on temporary migrant workers

In September 2021, Immigration New Zealand (INZ) announced the offer of a one-off residence visa category – the 2021 Resident Visa, to over 165,000 temporary migrant workers and their family members living in the country. The offer was a response to the backlog and growing numbers of applications that INZ was unable to attend to largely because of the lockdown during the COVID-19 pandemic. Drawing on relevant statistical data, news media reports and available academic publications, this research note examines how New Zealand’s sanitization policies during the pandemic affected the lives of temporary migrant workers who hold various work visas

Integrated and Control-Oriented Simulation Tool for Optimizing Urban Drainage System Operation

With the management and operation of urban drainage systems (UDS) becoming more complicated and difficult, integrated models aiming to control and manage the entire drainage system are under enormous demand. Ideally, integrated models, as a potential tool for meeting the increasing demands, should combine both conceptual and mechanistic models that merge all UDS components and balance simulation accuracy with time constraints. Within this context, our study introduces an innovative modeling software, Simuwater, which couples multiple principles, simulates multiple components, and combines optimized control functions, playing a role in the integrated simulation and overflow control application of UDS. The software has been utilized in a real-time case-control study in one city of China, and it obtained significant optimized operation results to reduce combined sewer overflow (CSO) by making full use of the storage facilities and actuators. As the Simuwater model continues to improve in depth and breadth, it will play an increasingly important role in more application scenarios of UDS

Stability Analysis of Shallow and Bias Loess Tunnel Based on Finite Difference Method

Based on the Mohr-Coulomb elastic-plastic model and the practical engineering background of Mopanshan tunnel, this paper applies the finite-difference software FLAC3D to simulate and analyse the whole process of loess tunnel construction. Then, it analyses the stability of the surrounding rock and sup-port structure after partial excavation of the loess tunnel under the shallow burying and unsymmetrical load-ing condition. The study showed that in the absence of support, the shear failure occurred to the top/upper pilot tunnel of the tunnel face, the failure zone under tensile stress happened to the shallow soil of the earth surface, and the soil of tunnel face appeared to be damaged. Finally, according to the analysis results, a rea-sonable construction method suitable for the shallow and bias loess tunnel is determined