Additional file 1 of Plasma exosomes improve peripheral neuropathy via miR-20b-3p/Stat3 in type I diabetic rats

Additional file 1: Figure S1. The diabetic model was successfully constructed after STZ injection. Figure S2. Internalization of plasma exosomes of sciatic nerve in NC rats. Figure S3. Biological distribution of plasma exosomes in vivo. Figure S4. Effects of plasma exosomes on RSC96 and DRG cells. Figure S5. Effects of plasma exosomes on RSC96 and DRG cells. Figure S6. Statistical analysis of pstat3/stat3. Figure S7. Characterization of ageing plasma exosomes. Figure S8. Ageing-exos did not improve nerve damage caused by high glucose. Figure S9. Ageing-exos augments the motor and sensory innervation of the targets. Table S1. Random blood glucose and total cholesterol levels after exosome treatment. Table S2. Random blood glucose and total cholesterol levels after miR-20b-3p agomir treatment. Table S3. Sequence information used in the article. Table S4. Reagent information used in the article