Application of Fisher's Discriminant Method and Bayes' Discriminant Method Based on “R Language Analysis” as an Example

Discriminant analysis is a statistical discriminant and grouping technique, which uses the sample data of the research object to find a discriminant rule, which is called a discriminant function, which is used to explain the difference between two or more groups of groups and can classify a new product. The data determines which of the known types the new product belongs to. This paper discusses the discriminant analysis of Fisher's discriminant method and Bayes' discriminant method, and shows the application of the two methods in real life and the difference between them on the basis of R language

Comparison of Gaia DR2 Parallaxes of Stars with VLBI Astrometry

We compare the parallaxes of stars from VLBI astrometry in the literature to those in the Gaia DR2 catalog. Our full sample contains young stellar objects, evolved AGB stars, pulsars and other radio stars. Excluding AGB stars, which show significant discrepancies between Gaia and VLBI parallaxes, and stars in binary systems, we obtain an average, systematic, parallax offset of $-75 \pm 29~\mu$as for Gaia DR2, consistent with their estimate of a parallax zero-point between $-100$ and 0 $\mu$as.Comment: Accepted by Ap

The Parallax of the Red Hypergiant VX Sgr with Accurate Tropospheric Delay Calibration

We report astrometric results of VLBI phase-referencing observations of 22 GHz \hho\ masers emission toward the red hypergiant \vxsgr, one of most massive and luminous red hypergiant stars in our Galaxy, using the Very Long Baseline Array. A background source, \Jtwoze, projected 4\d4 from the target \vxsgr, was used as the phase reference. For the low declinations of these sources, such a large separation normally would seriously degrade the relative astrometry. We use a two-step method of tropospheric delay calibration, which combines the VLBI geodetic-block (or GPS) calibration with an image-optimization calibration, to obtain a trigonometric parallax of $0.64\pm0.04$ mas, corresponding to a distance of 1.56$^{+0.11}_{-0.10}$ kpc. The measured proper motion of \vxsgr\ is $0.36\pm0.76$ and $-2.92\pm0.78$ \masy\ in the eastward and northward directions. The parallax and proper motion confirms that \vxsgr\ belong to the Sgr OB1 association. Rescaling bolometric luminosities in the literature to our parallax distance, we find the luminosity of \vxsgr~is $(1.95 \pm 0.62) \times 10^5$ \Lsun, where the uncertainty is dominated by differing photometry measurements.Comment: 16 pages, 10 figures, accepted by Ap

Building the Multi-layer Theory of Association Semantic based on the Power-law Distribution of Linking Keywords

Abstract-Web information contain plentiful, significant knowledge which is eager to be explored by users. Effective semantic layered technology not only can provide theoretical support for knowledge discovery in Web resources, but also can improve the searching efficiency of the related information system. This paper builds the multi-layer theory of association semantic based on the power-law distribution of linking keywords. First, some experiments of four types of keywords with different linking role are done to discover the possible distribution law. Experiment results show that four types of keywords are all reveal power-law distribution. Then, based on the discovered power-law distribution, the multi-layer theory of association semantic is built. The multi-layer theory of association semantic can provide a theoretical support for knowledge recommendation with different particle size on Association Link Network (ALN). Keywords-Association Link Network, power-law distribution, multi-layer theory of association semantic, knowledge discovery in Web resources

GmNAC5, a NAC Transcription Factor, Is a Transient Response Regulator Induced by Abiotic Stress in Soybean

GmNAC5 is a member of NAM subfamily belonging to NAC transcription factors in soybean (Glycine max (L.) Merr.). Studies on NAC transcription factors have shown that this family functioned in the regulation of shoot apical meristem (SAM), hormone signalling, and stress responses. In this study, we examined the expression levels of GmNAC5. GmNAC5 was highly expressed in the roots and immature seeds, especially strongly in immature seeds of 40 days after flowering. In addition, we found that GmNAC5 was induced by mechanical wounding, high salinity, and cold treatments but was not induced by abscisic acid (ABA). The subcellular localization assay suggested that GmNAC5 was targeted at nucleus. Together, it was suggested that GmNAC5 might be involved in seed development and abiotic stress responses in soybean

Secondary infection with Streptococcus suis serotype 7 increases the virulence of highly pathogenic porcine reproductive and respiratory syndrome virus in pigs

<p>Abstract</p> <p>Background</p> <p>Porcine reproductive and respiratory syndrome virus (PRRSV) and <it>Streptococcus suis </it>are common pathogens in pigs. In samples collected during the porcine high fever syndrome (PHFS) outbreak in many parts of China, PRRSV and <it>S. suis </it>serotype 7 (SS7) have always been isolated together. To determine whether PRRSV-SS7 coinfection was the cause of the PHFS outbreak, we evaluated the pathogenicity of PRRSV and/or SS7 in a pig model of single and mixed infection.</p> <p>Results</p> <p>Respiratory disease, diarrhea, and anorexia were observed in all infected pigs. Signs of central nervous system (CNS) disease were observed in the highly pathogenic PRRSV (HP-PRRSV)-infected pigs (4/12) and the coinfected pigs (8/10); however, the symptoms of the coinfected pigs were clearly more severe than those of the HP-PRRSV-infected pigs. The mortality rate was significantly higher in the coinfected pigs (8/10) than in the HP-PRRSV- (2/12) and SS7-infected pigs (0/10). The deceased pigs of the coinfected group had symptoms typical of PHFS, such as high fever, anorexia, and red coloration of the ears and the body. The isolation rates of HP-PRRSV and SS7 were higher and the lesion severity was greater in the coinfected pigs than in monoinfected pigs.</p> <p>Conclusion</p> <p>HP-PRRSV infection increased susceptibility to SS7 infection, and coinfection of HP-PRRSV with SS7 significantly increased the pathogenicity of SS7 to pigs.</p

The parallax and 3D kinematics of water masers in the massive star-forming region G034.43+0.24

We report a trigonometric parallax measurement of 22 GHz water masers in the massive star-forming region G034.43+0.24 as part of the Bar and Spiral Structure Legacy (BeSSeL) Survey using the Very Long Baseline Array. The parallax is 0.330$\pm$50.018 mas, corresponding to a distance of $3.03^{+0.17}_{-0.16}$ kpc. This locates G034.43+0.24 near the inner edge of the Sagittarius spiral arm and at one end of a linear distribution of massive young stars which cross nearly the full width of the arm. The measured 3-dimensional motion of G034.43+0.24 indicates a near-circular Galactic orbit. The water masers display arc-like distributions, possibly bow shocks, associated with winds from one or more massive young stars

Benefits of Huang Lian mediated by gut microbiota on HFD/STZ-induced type 2 diabetes mellitus in mice

BackgroundHuang Lian (HL), one of the traditional Chinese medicines (TCMs) that contains multiple active components including berberine (BBR), has been used to treat symptoms associated with diabetes for thousands of years. Compared to the monomer of BBR, HL exerts a better glucose-lowering activity and plays different roles in regulating gut microbiota. However, it remains unclear what role the gut microbiota plays in the anti-diabetic activity of HL.MethodsIn this study, a type 2 diabetes mellitus (T2DM) mouse model was induced with a six-week high-fat diet (HFD) and a one-time injection of streptozotocin (STZ, 75 mg/kg). One group of these mice was administrated HL (50 mg/kg) through oral gavage two weeks after HFD feeding commenced and continued for four weeks; the other mice were given distilled water as disease control. Comprehensive analyses of physiological indices related to glycolipid metabolism, gut microbiota, untargeted metabolome, and hepatic genes expression, function prediction by PICRUSt2 were performed to identify potential mechanism.ResultsWe found that HL, in addition to decreasing body fat accumulation, effectively improved insulin resistance by stimulating the hepatic insulin-mediated signaling pathway. In comparison with the control group, HL treatment constructed a distinct gut microbiota and bile acid (BA) profile. The HL-treated microbiota was dominated by bacteria belonging to Bacteroides and the Clostridium innocuum group, which were associated with BA metabolism. Based on the correlation analysis, the altered BAs were closely correlated with the improvement of T2DM-related markers.ConclusionThese results indicated that the anti-diabetic activity of HL was achieved, at least partly, by regulating the structure of the gut microbiota and the composition of BAs

Development of PCR-based markers associated with powdery mildew resistance using bulked segregant analysis (BSA-seq) in melon

Powdery mildew (PM) is a fungus that causes disease in both the field and the greenhouse. Utilizing resistant cultivars is the most effective approach of disease management. To develop insertion-deletion (InDel) markers associated to this trait, the whole genomes of the PM resistant line M17050 (P1) and the PM-susceptible line 28-1-1 (P2) were sequenced. A total of 1 200 InDels, with an average of 100 markers per chromosome, were arbitrarily chosen from the sequencing data for experimental validation. One hundred InDel markers were ultimately selected due to their informative genetic bands. Further, an F2 segregating population of melons generated from these two parents was inoculated by the PM pathogen. Based on bulk segregant analysis (BSA) using these 100 InDel markers, the powdery mildew resistance was associated with the genomic region LVpm12.1 on the melon chromosome 12. This region overlapped the previously described quantitative trait locus (QTL)-hotspot area carrying multiple PM-resistance QTLs. Moreover, conventional QTL mapping analysis was done, which located LVpm12.1 in the region between 22.72 and 23.34 Mb, where three highly polymorphic InDel markers MInDel89, MInDel92, and MInDel93 were detected. Therefore, these markers could be used to track this resistance locus in melon while the lines carrying this locus could be employed in PM melon resistance breeding programs after validation tests