23 research outputs found
The Baryon Fractions and Mass-to-Light Ratios of Early-Type Galaxies
We jointly model 22 early-type gravitational lens galaxies with stellar
dynamical measurements using standard CDM halo models. The sample is
inhomogeneous in both its mass distributions and the evolution of its stellar
populations unless the true uncertainties are significantly larger than the
reported measurement errors. In general, the individual systems cannot
constrain halo models, in the sense that the data poorly constrains the stellar
mass fraction of the halo. The ensemble of systems, however, strongly
constrains the average stellar mass represented by the visible galaxies to
of the halo mass if we neglect adiabatic compression, rising to
of the halo mass if we include adiabatic compression. Both
estimates are significantly smaller than the global baryon fraction,
corresponding to a star formation efficiency for early-type galaxies of
. In the adiabatically compressed models, we find an average local
B-band stellar mass-to-light ratio of (M/L)_0 =
(7.2\pm0.5)(M_{\sun}/L_{\sun}) that evolves by
per unit redshift. Adjusting the isotropy of the stellar orbits has little
effect on the results. The adiabatically compressed models are strongly favored
if we impose either local estimates of the mass-to-light ratios of early-type
galaxies or the weak lensing measurements for the lens galaxies on 100 kpc
scales as model constraints.Comment: 9 figure
Polydopamine-Decorated Microcomposites Promote Functional Recovery of an Injured Spinal Cord by Inhibiting Neuroinflammation
Neuroinflammation following spinal cord injury usually aggravates spinal cord damage. Many inflammatory cytokines are key players in neuroinflammation. Owing largely to the multiplicity of cytokine targets and the complexity of cytokine interactions, it is insufficient to suppress spinal cord damage progression by regulating only one or a few cytokines. Herein, we propose a two-pronged strategy to simultaneously capture the released cytokines and inhibit the synthesis of new ones in a broad-spectrum manner. To achieve this strategy, we designed a core/shell-structured microcomposite, which was composed of a methylprednisolone-incorporated polymer inner core and a biocompatible polydopamine outer shell. Thanks to the inherent adhesive nature of polydopamine, the obtained microcomposite (MP-PLGA@PDA) efficiently neutralized the excessive cytokines in a broad-spectrum manner within 1 day after spinal cord injury. Meanwhile, the controlled release of immunosuppressive methylprednisolone reduced the secretion of new inflammatory cytokines. Benefiting from its efficient and broad-spectrum capability in reducing the level of cytokines, this core/shell-structured microcomposite suppressed the recruitment of macrophages and protected the injured spinal cord, leading to an improved recovery of motor function. Overall, the designed microcomposite successfully achieved the two-pronged strategy in cytokine neutralization, providing an alternative approach to inhibit neuroinflammation in the injured spinal cord.Peer reviewe
Functionalization of Carbon Nanotubes in Polystyrene and Properties of Their Composites: A Review
The inherent π–π interfacial interaction between carbon nanotubes (CNTs) and polystyrene (PS) makes the CNT/PS composite a representative thermoplastic nanocomposite. However, the strong van der Waals force among CNTs poses challenges to achieving effective dispersion. This review provides an overview of various CNT functionalization methods for CNT/PS composites, encompassing covalent grafting with PS-related polymers and non-covalent modification. A focus in this section involves the pre-introduction surface modification of CNTs with PS or PS-related polymers, substantially enhancing both CNT dispersibility and interfacial compatibility within the PS matrix. Furthermore, a comprehensive summary of the mechanical, electrical, thermal, and electromagnetic shielding properties of CNT/PS nanocomposites is provided, offering an overall understanding of this material. The surface modification methods of CNTs reviewed in this paper can be extended to carbon material/aromatic polymer composites, assisting researchers in customizing the optimal surface modification methods for CNTs, maximizing their dispersibility, and fully unleashing the various properties of CNTs/polymer composites. Additionally, high-performance CNTs/PS composites prepared using appropriate CNT modification methods have potential applications in areas such as electronic devices, sensors, and energy storage and conversion
Exploring Microstructure, Wear Resistance, and Electrochemical Properties of AlSi10Mg Alloy Fabricated Using Spark Plasma Sintering
Al-Si-Mg alloy has excellent casting performance due to its high silicon content, but the coarse eutectic silicon phase can lead to a decrease in its mechanical properties. Samples of AlSi10Mg alloy were prepared by using a spark plasma sintering method, and it was found that sintering temperature has a significant impact on the grain size, eutectic silicon size and wear and corrosion properties after heat treatment. At a sintering temperature of 525 °C, the alloy exhibits the best wear performance with an average friction coefficient of 0.29. This is attributed to the uniform precipitation of fine eutectic silicon phases, significantly improving wear resistance and establishing adhesive wear as the wear mechanism of AlSi10Mg alloy at room temperature. The electrochemical performance of AlSi10Mg sintered at 500 °C is the best, with Icorr and Ecorr being 1.33 × 10−6 A·cm−2 and −0.57 V, respectively. This is attributed to the refinement of grain size and eutectic silicon size, as well as the appropriate Si volume fraction. Therefore, optimizing the sintering temperature can effectively improve the performance of AlSi10Mg alloy
Study on the Electrochemical Removal Mechanism of Oxytetracycline by a Ti/IrO2-Ta2O5 Plate
In this study, a Ti/IrO2-Ta2O5 anode was prepared by a hydrothermal method, and the prepared electrode was characterized by techniques such as scanning electron microscopy, X-ray diffraction, and electron dispersive spectroscopy. At the same time, the anode characteristics before and after electrochemical experiments were analyzed. The electrode gradation mechanism of oxytetracycline is discussed. In the whole experimental process, the range of electrolysis conditions was determined by single factor experiment, and then the optimal removal condition of oxytetracycline was determined by orthogonal experiments. The removal rate of oxytetracycline reached 99.02% after 20 min of electrolysis under the following optimal conditions: a current of 0.500 A, plate spacing of 2 cm, Na2SO4 electrolyte concentration of 4 g/L, and solution pH of 3. Additionally, the mechanism of oxytetracycline removal was explored, free radical scavenging experiments were performed, and the degradation mechanism was inferred based on the changes in the ultraviolet absorption of the oxytetracycline solution before and after electrolysis. Then, based on the liquid chromatography–mass spectrometry data, seven possible compounds and five possible removal pathways were proposed
Integrated metabolomic and transcriptomic analyses revealed the distribution of saponins in Panax notoginseng
Panax notoginseng is famous for its important therapeutic effects. Saponins are bioactive compounds found in different parts and developmental stages of P. notoginseng plants. Thus, it is urgently to study saponins distribution in different parts and growth ages of P. notoginseng plants. In this study, potential biomarkers were found, and their chemical characteristic differences were revealed through metabolomic analysis. High-performance liquid chromatography data indicated the higher content of saponins (i.e., Rg1, Re, Rd, and Rb1) in the underground parts than that in the aerial parts. 20(S)-Protopanaxadiol saponins were mainly distributed in the aerial parts. Additionally, the total saponin content in the 3-year-old P. notoginseng plant (188.0 mg/g) was 1.4-fold higher than that in 2-year-old plant (130.5 mg/g). The transcriptomic analysis indicated the tissue-specific transcription expression of genes, namely, PnFPS, PnSS, PnSE1, PnSE2, and PnDS, which encoded critical synthases in saponin biosyntheses. These genes showed similar expression patterns among the parts of P. notoginseng plants. The expression levels of these genes in the flowers and leaves were 5.2fold higher than that in the roots and fibrils. These results suggested that saponins might be actively synthesized in the aerial parts and transformed to the underground parts. This study provides insights into the chemical and genetic characteristics of P. notoginseng to facilitate the synthesis of its secondary metabolites and a scientific basis for appropriate collection and rational use of this plant. KEY WORDS: Panax notoginseng, Saponin, Growth years, Metabolomic analyses, Gene expressio
Integrated Chemical and Transcriptomic Analysis Reveals the Distribution of Protopanaxadiol- and Protopanaxatriol-Type Saponins in Panax notoginseng
Panax notoginseng is famous for its important therapeutic effects and commonly used worldwide. The active ingredients saponins have distinct contents in different tissues of P. notoginseng, and they may be related to the expression of key genes in the synthesis pathway. In our study, high-performance liquid chromatography results indicated that the contents of protopanaxadiol-(Rb1, Rc, Rb2, and Rd) and protopanaxatriol-type (R1, Rg1, and Re) saponins in below ground tissues were higher than those in above ground tissues. Clustering dendrogram and PCA analysis suggested that the below and above ground tissues were clustered into two separate groups. A total of 482 and 882 unigenes were shared in the below and above ground tissues, respectively. A total of 75 distinct expressions of CYPs transcripts (RPKM ≥ 10) were detected. Of these transcripts, 38 and 37 were highly expressed in the below ground and above ground tissues, respectively. RT-qPCR analysis showed that CYP716A47 gene was abundantly expressed in the above ground tissues, especially in the flower, whose expression was 31.5-fold higher than that in the root. CYP716A53v2 gene was predominantly expressed in the below ground tissues, especially in the rhizome, whose expression was 20.1-fold higher than that in the flower. Pearson’s analysis revealed that the CYP716A47 expression was significantly correlated with the contents of ginsenoside Rc and Rb2. The CYP716A53v2 expression was associated with the saponin contents of protopanaxadiol-type (Rb1 and Rd) and protopanaxatriol-type (R1, Rg1, and Re). Results indicated that the expression patterns of CYP716A47 and CYP716A53v2 were correlated with the distribution of protopanaxadiol-type and protopanaxatriol-type saponins in P. notoginseng. This study identified the pivotal genes regulating saponin distribution and provided valuable information for further research on the mechanisms of saponin synthesis, transportation, and accumulation
Heat Shock Treatment Promoted Callus Formation on Postharvest Sweet Potato by Adjusting Active Oxygen and Phenylpropanoid Metabolism
This study aimed to investigate that rapid high-temperature treatment (RHT) at an appropriate temperature could accelerate callus formation by effectively promoting the necessary metabolic pathways in sweet potato callus. In this study, the callus of sweet potato was treated with heat shock at 50, 65, and 80 °C for 15 min. The callus formation was observed within 1, 3, and 5 days, and the accumulation of intermediates in the metabolism of phenylpropane and reactive oxygen species and changes in enzyme activities were determined. The results showed that appropriate RHT treatment at 65 °C stimulated the metabolism of reactive oxygen species at the injury site of sweet potato on the first day, and maintained a high level of reactive oxygen species production and scavenging within 5 days. The higher level of reactive oxygen species stimulated the phenylalanine ammonia-lyase (PAL), 4-coumarate-CoA ligase and cinnamate-4-hydroxylase activities of the phenylpropane metabolic pathway, and promoted the rapid synthesis of chlorogenic acid, p-coumaric acid, rutin, and caffeic acid at the injury site, which stacked to form callus. By Pearson’s correlation analysis, catalase (CAT), PAL, and chlorogenic acid content were found to be strongly positively correlated with changes in all metabolites and enzymatic activities. Our results indicated that appropriate high-temperature rapid treatment could promote sweet potato callus by inducing reactive oxygen species and phenylpropane metabolism; moreover, CAT, PAL, and chlorogenic acid were key factors in promoting two metabolic pathways in sweet potato callus
Rhizospheric microbial communities are driven by Panax ginseng at different growth stages and biocontrol bacteria alleviates replanting mortality
The cultivation of Panax plants is hindered by replanting problems, which may be caused by plant-driven changes in the soil microbial community. Inoculation with microbial antagonists may efficiently alleviate replanting issues. Through high-throughput sequencing, this study revealed that bacterial diversity decreased, whereas fungal diversity increased, in the rhizosphere soils of adult ginseng plants at the root growth stage under different ages. Few microbial community, such as Luteolibacter, Cytophagaceae, Luteibacter, Sphingomonas, Sphingomonadaceae, and Zygomycota, were observed; the relative abundance of microorganisms, namely, Brevundimonas, Enterobacteriaceae, Pandoraea, Cantharellales, Dendryphion, Fusarium, and Chytridiomycota, increased in the soils of adult ginseng plants compared with those in the soils of 2-year-old seedlings. Bacillus subtilis 50-1, a microbial antagonist against the pathogenic Fusarium oxysporum, was isolated through a dual culture technique. These bacteria acted with a biocontrol efficacy of 67.8%. The ginseng death rate and Fusarium abundance decreased by 63.3% and 46.1%, respectively, after inoculation with B. subtilis 50-1. Data revealed that microecological degradation could result from ginseng-driven changes in rhizospheric microbial communities; these changes are associated with the different ages and developmental stages of ginseng plants. Biocontrol using microbial antagonists alleviated the replanting problem. KEY WORDS: Panax ginseng, Microbial communities, Replanting problem, High-throughput sequencing, Different ages, Bioremediatio